Regional citrate anticoagulation (RCA) control system and RCA target control infusion pump

Abstract

The present invention relates to a regional citrate anticoagulation (RCA) control system and a RCA target control infusion pump. The RCA control system is suitable for a continuous renal replacement therapy (CRRT) process and comprises a first peristaltic pump speed calculation module and a second peristaltic pump speed calculation module, the first peristaltic pump speed calculation module is used for calculating an infusion speed of sodium citrate, the second peristaltic pump speed calculation module is used for calculating an infusion speed of a calcium supplement drug, the RCA target control infusion pump comprises a control module and the first peristaltic pump and the second peristaltic pump which are respectively connected with the control module, and the control module comprises the RCA control system. The RCA control system can accurately calculate dosages of the sodium citrate and calcium supplement drug required under different setting conditions, and maintains full anticoagulation of a filter part and a stable blood calcium level of patients. The RCA target control infusion pump can automatically adjust the dosages of the calcium supplement drug and sodium citrate according to changes of settings of blood purification machines.

Description

technical field [0001] The invention belongs to the technical field of medical devices and relates to an RCA control system and an RCA target-controlled infusion pump. Background technique [0002] Continuous renal replacement therapy (CRRT) is one of the most important means of support in intensive care medicine. RCA not only avoids the risks of bleeding and thrombocytopenia caused by heparin anticoagulation, but also reduces the activation of coagulation factors and inflammatory factors in the body. In 2012, the Global Organization for Improving the Prognosis of Renal Diseases recommended RCA as the preferred anticoagulant method for CRRT in patients with acute kidney injury. But there are still some problems in the current RCA application. [0003] At present, the clinical use of RCA is still very limited, mainly because the operation is complicated, and the ionized calcium (ionized calcium, iCa) level needs to be frequently monitored in clinical use to maintain blood c...

AI Technical Summary

Problems solved by technology

[0012] The purpose of the present invention is to overcome the shortcomings of the need to frequently adjust the infusion rate of sodium citrate and calcium supplements according to the test results in the existing RCA (local sodium citrate anticoagulant) technology, and solve the scope of application that exists in the current mathematical model To solve many problems such as limitations, inaccurate calculation results and lack of ability to correct blood calcium in patients with abnormal blood calcium levels, an RCA control system and an RCA target-controlled infusion pump are provided.

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