3 results about "Citrate anticoagulation" patented technology

The invention provides an improved infusion system and medicine for citric acid anticoagulation applied to continuous blood purification (CBP). According to the system, an on-line conductivity sensor is additionally arranged in a citric acid infusion pipeline, real-time monitoring and intelligent feedback control over the concentration of citric acid are achieved, the infusion pump speed can be automatically adjusted, and it is ensured that the concentration is maintained within the set range (3.0-4.0 mmol / L). In addition, the system is further provided with a sound-light alarm function, an alarm is given out when the concentration fluctuation exceeds 0.5 mmol / L, and the treatment safety is guaranteed. Meanwhile, according to the optimized citric acid formula, the risk of hypocalcemia is effectively reduced by accurately adjusting the pH value of the solution and adding EDTA disodium. According to the system, through accurate monitoring, automatic adjustment and efficient pipeline management, the safety and effect of CBP treatment are greatly improved, and the system is suitable for treatment requirements of various complex patients. Through verification of the embodiment, the traditional Chinese medicine composition shows a good treatment effect and safety in practical application, and has a wide clinical popularization prospect.

A method for controlling an infusion rotation speed of a citrate pump comprises: collecting parameters of the regional citrate anticoagulation infusion system (S101), the parameters include blood flow velocity and red blood cell hematocrit; determining a citrate infusion volume per unit time based on the parameters (S102); and controlling the infusion rotation speed of the citrate pump based on the citrate infusion volume per unit time (S103). A method for controlling an infusion rotation speed of a calcium pump includes: determining an amount of calcium supplementation required for the regional citrate anticoagulation infusion system (S201); and controlling the infusion rotation speed of the calcium pump according to the amount of calcium supplementation (S202). The citrate infusion volume per unit time and the amount of calcium supplementation required by the regional citrate anticoagulation infusion system is determined through specific formulas.

The utility model discloses a novel continuous blood purification pipeline which comprises a purifier and a vein pot which are connected with each other, one end of the purifier is connected with the artery end of a human body, a 5% sodium citrate liquid bag and a pre-replacement liquid bag are connected between the artery end and the purifier, the purifier is connected with a dialysate bag, one end of the vein pot is connected with the vein end of the human body, and the other end of the vein pot is connected with the vein end of the human body. A rear replacement liquid bag is connected to the liquid pipe between the vein pot and the human vein end through a connecting assembly, a replacement liquid assembly of the machine and a replacement liquid extension assembly. According to the utility model, non-planned off-machine operation caused by vein kettle blood coagulation during local citric acid anticoagulation can be reduced, blood loss is reduced, and blood coagulation factor consumption caused by vein kettle blood coagulation and influence on the blood coagulation function are reduced; the use amount of citric acid can be reduced, blood coagulation in a vein pot is prevented, the occurrence rate of citric acid anticoagulation complications is reduced, the use of pumps is reduced, the risk of balance imbalance caused by inconsistent pump speeds is reduced, a finished product replacement liquid with higher calcium concentration can be used, and bone calcium loss is reduced.