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Gel dressing for preventing and inhibiting HPV virus infection and preparation method thereof

An HPV virus and gel technology is applied in the field of gel dressings for preventing and inhibiting HPV virus infection and the preparation thereof, and can solve the problems of affecting the exertion of drugs, poor drug release, easy deformation of suppositories and the like

Inactive Publication Date: 2020-04-14
重庆宫妙生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drug treatment of gynecological diseases is mainly administered through the vagina. Currently, the commonly used formulations for vaginal administration mainly include suppositories, effervescent tablets, lotions, capsules, etc., but these dosage forms have more or less defects, which affect the efficacy of drugs.
Such as suppositories, the drug release is not good, the contact surface with the vaginal grinding is small, it is difficult to penetrate into the grinding folds, and the suppository is easily deformed when the temperature is high, and the stability is not good; such as capsules, the drug is not easy to release, and it is affected by the disintegration of the capsule. Poor effect on coating surface

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A gel dressing for preventing and inhibiting HPV virus infection, which is composed of hydrogel and Chinese medicine extract uniformly dispersed in the hydrogel, and the components of the Chinese medicine extract are calculated in parts by weight: 15 parts of coconut extract , 15 parts of Sophora flavescens extract, 6 parts of Equisetum extract, 4 parts of Brucea javanica extract, 12 parts of Cnidium fruit extract, 20 parts of anthocyanin, 6 parts of carrageenan, 3 parts of natural balance factor, 4 parts of borneol The hydrogel includes sodium hydroxymethylcellulose, ethylparaben, propylene glycol, mannitol, antibacterial peptide, glycerol, water-based lubricant powder, diethanolamine, and distilled water.

[0024] The components of the hydrogel are calculated in parts by weight: 7 parts of sodium hydroxymethylcellulose, 2 parts of ethylparaben, 12 parts of propylene glycol, 5 parts of mannitol, 5 parts of antibacterial peptides, and 12 parts of glycerol , 9 parts of w...

Embodiment 2

[0034] A gel dressing for preventing and inhibiting HPV virus infection, which is composed of hydrogel and Chinese medicine extract uniformly dispersed in the hydrogel, and the components of the Chinese medicine extract are calculated in parts by weight: 16 parts of coconut extract , Sophora flavescens extract 20 parts, Equisetum extract 8 parts, Brucea javanica extract 5 parts, Cnidium chinensis extract 13 parts, anthocyanins 23 parts, carrageenan 8 parts, natural balance factor 4 parts, borneol 5 parts The hydrogel includes sodium hydroxymethylcellulose, ethylparaben, propylene glycol, mannitol, antibacterial peptide, glycerol, water-based lubricant powder, diethanolamine, and distilled water.

[0035] The components of the hydrogel are calculated in parts by weight: 8 parts of sodium hydroxymethylcellulose, 3 parts of ethylparaben, 14 parts of propylene glycol, 6 parts of mannitol, 6 parts of antibacterial peptides, and 14 parts of glycerol , 12 parts of water-based lubrica...

Embodiment 3

[0045] A gel dressing for preventing and inhibiting HPV virus infection, which is composed of hydrogel and Chinese medicine extract uniformly dispersed in the hydrogel, and the components of the Chinese medicine extract are calculated in parts by weight: 18 parts of coconut extract , 25 parts of Sophora flavescens extract, 10 parts of Equisetum extract, 7 parts of Brucea javanica extract, 15 parts of Cnidium fruit extract, 26 parts of anthocyanin, 10 parts of carrageenan, 5 parts of natural balance factor, 6 parts of borneol The hydrogel includes sodium hydroxymethylcellulose, ethylparaben, propylene glycol, mannitol, antibacterial peptide, glycerol, water-based lubricant powder, diethanolamine, and distilled water.

[0046] The components of the hydrogel are calculated in parts by weight: 10 parts of sodium hydroxymethylcellulose, 4 parts of ethylparaben, 16 parts of propylene glycol, 8 parts of mannitol, 8 parts of antibacterial peptides, and 16 parts of glycerol , 15 parts ...

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PUM

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Abstract

The invention discloses a gel dressing for preventing and inhibiting HPV virus infection. The gel dressing is prepared from hydrogel and traditional Chinese medicine extracts uniformly dispersed in the hydrogel, wherein the traditional Chinese medicine extracts include radix sophorae flavescentis extract, scouring rush extract, brucea javanica extract, fructus cnidii extract, anthocyanin, carrageenan, natural equilibrium factors and borneol; and the hydrogel includes carboxymethyl cellulose sodium, ethylparaben, propylene glycol, mannitol, antibacterial peptide, glycerol, a water-based powdered lubricant, diethanol amine and distilled water. By adopting the technical scheme, the gel dressing has effects of moistening the skin, protecting the heart, conditioning the premenstrual syndrome and the like by adding anthocyanin; and the gel dressing can effectively improve human immunity, moisten genital tracts, protect mucous membranes and effectively relieve vaginal dryness and other symptoms by adding carrageenan.

Description

technical field [0001] The invention relates to the technical field of female hygiene care products, in particular to a gel dressing for preventing and inhibiting HPV virus infection and a preparation method thereof. Background technique [0002] Human papillomavirus (HPV) infection is one of the most common gynecological infectious diseases. According to reports, the pathogenesis of cervical cancer may be related to HPV infection, and HPV mainly induces cervical epithelial sarcoma and malignant tumors by invading cervical epithelial cells. According to the severity of the lesions it causes, HPV viruses can be divided into low-risk and high-risk types. Among them, interferon treatment is the most common, while traditional Chinese medicine treatment can relatively reduce adverse reactions, avoid damage to normal organs, and reduce the psychological burden of patients, so it has certain advantages. [0003] At present, the drug treatment of gynecological diseases is mainly a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/489A61K38/00A61K9/06A61K47/38A61K47/10A61K47/26A61K47/14A61K47/18A61K47/42A61P15/00A61P31/20A61K31/353A61K31/731A61K31/045
CPCA61K9/0034A61K9/06A61K31/045A61K31/353A61K31/731A61K36/11A61K36/185A61K36/234A61K36/489A61K38/00A61K47/10A61K47/14A61K47/18A61K47/26A61K47/38A61K47/42A61K2236/331A61K2236/333A61K2236/39A61P15/00A61P31/20A61K2300/00
Inventor 杨国军蒋清昀
Owner 重庆宫妙生物科技有限公司
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