A kind of absorbable anti-adhesion dressing and preparation method thereof

Abstract

The invention provides an absorbable anti-adhesion dressing. The absorbable anti-adhesion dressing is composed of a hydrophobic layer, a hydrophilic layer and a protective layer from the side close to the skin, and the hydrophobic layer is polycaprolactone loaded with microspheres. / chitosan porous film, the material of the hydrophilic layer is one or more of hyaluronic acid, gelatin, sodium alginate or keratin, and the protective layer is composed of eggshell membrane and modified polyurethane film The present invention also provides a preparation method for an absorbable anti-adhesion dressing, the prepared absorbable anti-adhesion dressing can be degraded and absorbed, does not need to be replaced frequently, maintains a moist environment conducive to wound repair, has excellent mechanical properties, and has an antibacterial effect Strong, can promote the one-way absorption of drugs, improve the utilization rate of the dressing, and the problem of adhesion to the wound surface will not occur when the dressing is changed, preventing secondary damage.

Description

technical field [0001] The invention belongs to the field of biological materials, in particular to an absorbable anti-adhesion dressing and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body and has the functions of retaining moisture in the body, preventing excessive heat dissipation, ventilating and preventing bacterial invasion. In daily life, wounds, abrasions, skin ulcers, burns and other wounds inevitably appear on the skin surface of the human body. If these wounds are not treated effectively, they may lead to a wider range of injuries, such as: infection, loss of body fluids, and various complications disease etc. [0003] If only a superficial layer or a small area of ​​the skin is damaged, the new skin will regenerate itself, but if it is severely traumatized, the skin cannot repair itself, and medical dressings are usually attached to promote wound healing. Traditional dressings such as absorbent cotton g...

AI Technical Summary

Problems solved by technology

Traditional dressings such as absorbent cotton gauze, cotton pads, and Vaseline gauze have a net-like weaving structure. Although they are cheap, the manufacturing process is relatively simple, the source of raw materials is wide, the texture is soft, and they have strong absorption capacity, they can prevent the accumulation of exudate on the wound surface. It also has a certain degree of protective effect on wound healing, but it cannot keep the wound moist, which will delay wound healing, poor barrier effect after dressing penetration, easy to cause exogenous infection, poor hemostatic effect, and wound granulation tissue is easy to grow into the mesh of the dressing In the eyes, when the dressing is changed, it is easy to adhere to the wound surface, damage the new granulation tissue and cause pain, and sometimes the exudate will leak through the dressing, adhere to clothing and dust, and cause wound infection

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