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A kind of compound Nuangongzhitong foot bath effervescent tablet and preparation method thereof

A technology of effervescent tablets and foot baths, which is applied in the direction of non-central analgesics, medical formulas, and medical preparations with non-active ingredients, etc., can solve the problems of few researches on effervescent tablets of traditional Chinese medicine, and achieve the solution of splits and instability, Good effervescent effect, excellent quality effect

Active Publication Date: 2022-01-07
四川智谷藏御堂生物科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Foreign scholars' research on effervescent tablets in western medicine has been quite mature, but there are few studies on effervescent tablets in traditional Chinese medicine.

Method used

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  • A kind of compound Nuangongzhitong foot bath effervescent tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1 Preparation of Compound Nuan Gong Zhi Pain Foot Bath Effervescent Tablet

[0041] Proportion by weight of raw materials: 30 parts of extract powder; 40 parts of citric acid monohydrate and sodium bicarbonate (molar ratio: 1:3.5); 5 parts of PEG6000; 2 parts of magnesium stearate; 23 parts of lactose;

[0042] Described extract powder is prepared by the following method:

[0043] Preparation method: Weigh motherwort, 10g each of safflower, Mildew Spatholobus, Radix Paeoniae Alba, Artemisia argyi, and Galangal, add 1000mL of 70% ethanol solution, put it in a 2000mL conical flask with a stopper, ultrasonicate for 40min, extract the same amount of 70% ethanol for 2 Second, take the filtrate by suction filtration, reclaim ethanol with a rotary evaporator, put the concentrated extract in an evaporating dish for drying in a water bath, and obtain a dry product; grind the dry product to obtain an extract powder;

[0044] The preparation method of compound Nuangongzhito...

Embodiment 2

[0050] Example 2 Preparation of Compound Nuan Gong Zhi Pain Foot Bath Effervescent Tablets

[0051] Proportion by weight of raw materials: 40 parts of extract powder; 35 parts of citric acid monohydrate and sodium bicarbonate (molar ratio: 1:3.5); 8 parts of PEG6000; 2 parts of magnesium stearate; 15 parts of lactose;

[0052] The preparation method of the extract powder and the preparation method of the compound Nuangongzhitong foot bath effervescent tablet are the same as in Example 1.

[0053] According to the quality standard evaluation in Table 1, the quality scores of the compound Nuangongzhitong foot bath effervescent tablet of this embodiment are as follows: 20 points for anti-adhesiveness, 18 points for tablet properties, 18 points for disintegration, 18 points for effervescent effect, and 20 points for dispersibility , 20 points for floaters; 114 points in total.

Embodiment 3

[0054] Example 3 Preparation of Compound Nuan Gong Zhi Pain Foot Bath Effervescent Tablets

[0055] Raw material ratio by weight: 30 parts of extract powder; 45 parts of citric acid monohydrate and sodium bicarbonate (1:3 molar ratio); 5 parts of PEG6000; 1 part of magnesium stearate; 19 parts of lactose;

[0056] The preparation method of the extract powder and the preparation method of the compound Nuangongzhitong foot bath effervescent tablet are the same as in Example 1.

[0057] According to the quality standard evaluation in Table 1, the quality scores of the compound Nuangongzhitong foot bath effervescent tablet of this embodiment are as follows: 18 points for anti-adhesiveness, 18 points for tablet properties, 18 points for disintegration, 18 points for effervescent effect, and 18 points for dispersibility , 20 points for floaters; a total of 110 points.

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Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, and specifically discloses a compound Nuangong analgesic foot bath effervescent tablet and a preparation method thereof. The preparation of the compound Nuangong Pain Relief Foot Bath Effervescent Tablet comprises the following components in parts by weight: 30-40 parts of extract powder; 35-50 parts of acid source and alkali source; 3-8 parts of PEG; 1 part of lubricant ~3 parts; filler 15~30 parts. The invention discloses a brand-new compound Nuan Gong pain-relieving foot bath effervescent tablet, provides a brand-new Nuan Gong pain-relieving foot bath product, and fills the market gap of such products. In addition, the effervescent tablet has excellent quality, better disintegration time and effervescent effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a compound Nuan Gong Zhi Pain Foot Bath Effervescent Tablet and a preparation method thereof. Background technique [0002] Dysmenorrhea (dysmenorrhea) is one of the most common symptoms of young women. It refers to uterine cramping pain during menstruation, accompanied by lower abdominal pain, backache, or combined with headache, dizziness, fatigue, nausea and other discomfort symptoms, which seriously affects modern young women. Learning, work and other life activities and quality. Dysmenorrhea is divided into primary dysmenorrhea and secondary dysmenorrhea. Primary dysmenorrhea is functional dysmenorrhea, which refers to the dysmenorrhea symptoms of dysmenorrhea in the first menstruation and every subsequent menstrual period, and its clinical examination has no obvious pelvic organs unusual phenomenon. Secondary dysmenorrhea is characterized...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/9062A61K47/12A61K47/26A61K47/10A61K47/02A61P15/00A61P29/00
CPCA61K36/533A61K36/286A61K36/486A61K36/71A61K36/65A61K36/282A61K36/9062A61K9/2013A61K9/2018A61K9/2031A61K9/2009A61K9/0007A61K9/0014A61P15/00A61P29/00A61K2236/33A61K2236/39A61K2300/00
Inventor 翟明张声源赵莹黄思涵李兰芳
Owner 四川智谷藏御堂生物科技有限责任公司
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