Medical moisturizing eye patch with good biocompatibility and lasting moisture retention and preparation method of medical moisturizing eye patch
A technology of eye patch and wet film, which is applied in the field of medical moisturizing eye patch and its preparation, can solve the problems of poor moisturizing effect of eye patch, achieve the effect of no toxic side effects, good water absorption and water locking effect, and increase moisture content
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Embodiment 1
[0034] A kind of medical moisturizing eye patch provided by the present embodiment, its preparation method comprises the following steps:
[0035]1) Preparation of component A: Stir the bacterial cellulose wet film in a sodium hydroxide solution with a mass fraction of 0.5% at 80°C for 1 h, wash to neutrality, and stir with a hydrogen peroxide solution with a mass fraction of 0.5% at room temperature for 4 h, wash Until the residual hydrogen peroxide is less than 0.5mg / L, component A is obtained;
[0036] 2) Prepare component B: Take glycerin and paraben, add 10% water, heat to 70°C in a water bath, stir and dissolve evenly; Put sodium hyaluronate and sodium hyaluronate with a molecular weight of 1,000-500,000 into 60% water in turn, and stir at room temperature for 24 hours; finally add the remaining water to 100%, and stir at room temperature for 10 minutes; wherein, component B includes the following mass fractions: Raw materials: 0.5% glycerin, 0.05% sodium hyaluronate wi...
Embodiment 2
[0040] A kind of medical moisturizing eye patch provided by the present embodiment, its preparation method comprises the following steps:
[0041] 1) Preparation of component A: Stir the bacterial cellulose wet film in a sodium hydroxide solution with a mass fraction of 1% at 90° C. for 1.5 h, wash to neutrality, and stir with a hydrogen peroxide solution with a mass fraction of 2% at room temperature for 5 h. Wash until residual hydrogen peroxide < 0.5mg / L to obtain component A;
[0042] 2) Prepare component B: take glycerin and paraben, add 15% water, heat to 75°C in a water bath, stir and dissolve evenly; Sodium hyaluronate and sodium hyaluronate with a molecular weight of 1,000-500,000 were put into 65% water in sequence, and stirred at room temperature for 24 hours; finally, the remaining water was added to 100%, and stirred at room temperature for 15 minutes; wherein, component B included the following mass fractions Raw materials: 3% glycerin, 2.5% sodium hyaluronate w...
Embodiment 3
[0046] A kind of medical moisturizing eye patch provided by the present embodiment, its preparation method comprises the following steps:
[0047] 1) Preparation of component A: Stir the bacterial cellulose wet film in a sodium hydroxide solution with a mass fraction of 1.5% at 100°C for 2 hours, wash to neutrality, and stir with a hydrogen peroxide solution with a mass fraction of 3% at room temperature for 6 hours, wash Until the residual hydrogen peroxide is less than 0.5mg / L, component A is obtained;
[0048] 2) Prepare component B: take glycerin and paraben, add 20% water, heat to 80°C in a water bath, and stir evenly; then dissolve the dissolved glycerin and paraben, hyaluronic acid with a molecular weight higher than 500,000 Sodium and sodium hyaluronate with a molecular weight of 1,000-500,000 are placed in 70% water in sequence, and stirred at room temperature for 24 hours; finally, the remaining water is added to 100%, and stirred at room temperature for 20 minutes; ...
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