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A kind of pharmaceutical composition for treating oral ulcer and preparation method thereof

A technology for oral ulcers and compositions, applied in the field of pharmaceutical compositions for the treatment of oral ulcers and the field of preparation thereof, can solve the problems of easy recurrence of oral ulcers, poor patient compliance, long treatment time, etc. good effect

Active Publication Date: 2021-12-14
北京斯利安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, the above-mentioned medicines for the treatment of oral ulcers have a long treatment time, poor curative effect, easy recurrence after the treatment of oral ulcers, and have certain irritation during the treatment process, and the patient's compliance is relatively poor.

Method used

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  • A kind of pharmaceutical composition for treating oral ulcer and preparation method thereof
  • A kind of pharmaceutical composition for treating oral ulcer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A pharmaceutical composition, in parts by weight, comprising the following components: 10 parts of Coptidis Rhizoma, 5 parts of Phellodendron Cortex, 5 parts of Houttuynia cordata, 4 parts of Kudiding, 5 parts of Rehmannia glutinosa, 5 parts of Bamboo Leaf, and 3 parts of Borneol , 10 parts of dried blood, 2 parts of asarum, 5 parts of lemon, 3 parts of aloe vera, 3 parts of mint extract, and 1 part of folic acid.

[0047] The preparation method of above-mentioned pharmaceutical composition, comprises the steps:

[0048] S1. Take the extracts of Coptidis Rhizoma Coptidis, Phellodendron Cortex, Houttuynia cordata, Kudiding, Rehmannia glutinosa, Bamboo Leaf, Blood Dragon, Asarum, Lemon, Aloe Vera, Peppermint extracts according to the proportioning, mix them evenly, and use 20% ethanol as the concentration by weight. Solvent leaching of the bulk drug, warm soaking and extraction at 35°C, the number of extractions is 12 times, each extraction time is 1.5 hours, and the amou...

Embodiment 2

[0052] A pharmaceutical composition, in parts by weight, comprising the following components: 20 parts of Coptidis Rhizoma, 12 parts of Phellodendron Cortex, 10 parts of Houttuynia cordata, 7 parts of Kudiding, 10 parts of Rehmannia glutinosa, 10 parts of Bamboo Leaf, and 6 parts of Borneol , 15 parts of dried blood, 5 parts of asarum, 10 parts of lemon, 8 parts of aloe vera, 8 parts of mint extract, and 5 parts of folic acid.

[0053] The preparation method of above-mentioned pharmaceutical composition, comprises the steps:

[0054] S1. Take the extracts of Coptidis Rhizoma Coptidis, Phellodendron Cortex, Houttuynia cordata, Kudiding, Rehmannia glutinosa, Bamboo Leaf, Blood Dragon, Asarum, Lemon, Aloe Vera, Peppermint extracts according to the proportioning, mix well, and use 22% ethanol as the concentration by weight Solvent leaching the raw material medicine, warm soaking extraction at 37°C, the number of extractions is 15 times, each extraction time is 2.5 hours, the amoun...

Embodiment 3

[0058] A pharmaceutical composition, in parts by weight, comprising the following components: 15 parts of Coptidis Rhizoma, 9 parts of Phellodendron Cortex, 7 parts of Houttuynia cordata, 6 parts of Kudiding, 7 parts of Rehmannia glutinosa, 8 parts of Bamboo Leaf, and 5 parts of Borneol , 12 parts of dried blood, 3 parts of asarum, 7 parts of lemon, 6 parts of aloe vera, 6 parts of mint extract, and 3 parts of folic acid.

[0059] The preparation method of above-mentioned pharmaceutical composition, comprises the steps:

[0060] S1. Take the extracts of Coptidis Rhizoma Coptidis, Phellodendron Cortex, Houttuynia cordata, Kudiding, Rehmannia glutinosa, Bamboo Leaf, Dried Blood, Herba Asarum, Lemon, Aloe Vera, Peppermint extracts according to the proportioning ratio, mix well, and use 21% ethanol with a concentration of 21% by weight as Solvent leaching of the bulk drug, warm soaking and extraction at 36 ° C, the number of extractions is 14 times, each extraction time is 2 hours...

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Abstract

The present invention relates to the technical field of medicines, in particular to a pharmaceutical composition for treating oral ulcers and a preparation method thereof. The pharmaceutical composition comprises the following components in parts by weight: 10-20 parts of Coptis Rhizoma, 5-12 parts of Phellodendron Phellodendri 5-10 parts of Houttuynia cordata, 4-7 parts of Kudiding, 5-10 parts of Rehmannia glutinosa, 5-10 parts of light bamboo leaves, 3-6 parts of borneol, 10-15 parts of dried blood, 2-5 parts of Asarum 5-10 parts of lemon, 3-8 parts of aloe, 3-8 parts of peppermint extract, and 1-5 parts of folic acid. The advantage of no toxic side effects.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a pharmaceutical composition for treating oral ulcers and a preparation method thereof. Background technique [0002] Oral ulcer, commonly known as "oral sore", is a kind of localized oral mucosal ulcer injury characterized by periodic and repeated attacks, which can heal itself. However, due to the periodicity, recurrence and self-limiting characteristics of ulcers, it is generally difficult to heal in a short time , is a common ulcerative injury that occurs in the oral mucosa. It is more common in the inner lip, tongue, tongue abdomen, buccal mucosa, vestibular groove, soft palate and other parts. The mucosa in these parts lacks cornified layer or poor keratinization. Tongue ulcers refer to oral ulcers that occur on the tongue and the abdomen of the tongue. When oral ulcers attack, the pain is severe, and the local burning pain is obvious. In severe cases, it will also affec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P1/02A61K31/045A61K31/519
CPCA61K36/718A61K36/756A61K36/78A61K36/66A61K36/804A61K36/899A61K31/045A61K36/889A61K36/896A61K36/268A61K36/752A61K36/886A61K36/534A61K31/519A61P1/02A61K2236/333A61K2236/55A61K2236/51A61K2300/00
Inventor 岳玉荣钟敏肖艳皎龚旭韩雅慧
Owner 北京斯利安药业有限公司
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