47results about How to "Relapse control" patented technology

The invention discloses a nourishing youth-keeping facial cleanser and a preparation method thereof. The facial cleanser comprises the substances of: coconut oil, rose infused oil, snow Lotus herb infused oil, gum Arabic, west tragacanth gum, coconut juice, coconut oil fatty acid disodium glutamate, sodium sarcosinate, fatty acid methyl ester sulfonate, glycerine, distilled water, white fungus extract liquid, watermelon extract liquid, lily extract liquid, sodium chloride, vitamin E, a cationic guar gum solution, an essence, ethyl paraben, and disodium edetate. The nourishing youth-keeping facial cleanser provided by the invention has a milky-white color, and is transparent and crystal. The facial cleaner has a proper viscosity, a proper consistency, good stability, rich foam, and good fragrance. The facial cleanser can provide nutrients and deep nourishing effects for facial skins. With the facial cleanser, the skins can turn moistened and elastic.

The invention discloses a herpes simplex virus I-type gene recombinant attenuated live vaccine and a preparation method thereof. The attenuated live vaccine is characterized in that: US2, US3, US4 and US5 genes in a genome and other duplicated or infected nonessential gene fragments are jointly knocked out, wherein other duplicated or infected nonessential gene fragments are US9-US12 genes. The method comprises the following steps: separating and identifying wild HSV-1 (herpes simplex virus-1) from blister fluid of a patient with remarkable herpes labialis and herpes progenitalis; propagating and extracting a complete genome of virus; co-transfecting a Vero cell with a shuttle vector containing homologous flanking sequences of 700bp to 2000bp on the left and right sides of a fluorescent expression gene and the HSV gene to be knocked off; and selecting the recombinant virus by using one or combination of multiple fluorescent protein genes serving as a marker under fluorescent microscope, and acquiring the required recombinant attenuated live vaccine after plaque purification.

The invention relates to a method for preparing facial mask soaking liquid, comprising the following steps of: cleaning and juicing aloe; decocting wild chrysanthemum water to obtain the liquid; finally mixing the two liquid to obtain the facial mask. The facial mask soaking liquid obtained by the method of the invention has actions of clearing away heat to reduce internal heat and effectively relieving pimples caused by heat-toxicity. The actions can be realized in one week through applying the soaking liquid for 6-10 min twice a week after the face is washed with facial cleanser. Simultaneously, the recurrence of the pimples can be prevented by using the facial mask soaking liquid for a long time.

The present invention relates to a pharmaceutical composition. The pharmaceutical composition comprises: at least one first therapeutically-active substance which is selected from carveol, thymol, eugenol, borneol, carvacrol and the isomers, derivatives and mixtures thereof; and at least one second therapeutically-active substance which is selected from an antiviral agent, an antitumour agent and an antiparasitic agent.

The invention discloses an application of MAGEA1 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The MAGEA1 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention relates to a traditional Chinese medicinal composition used for treating cirrhosis and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicinal composition used for treating the cirrhosis is prepared from the following raw material medicines in parts by weight: 10-70 parts of milkvetch, 5-20 parts of salvia miltiorrhiza, 10-30 parts of oriental wormwood, 10-15 parts of poria cocos, 10-15 parts of curcuma zedoary, 3-10 parts of safflower, 5-10 parts of radix bupleuri, 10-15 parts of Chinese angelica, 15-20 parts of longhairy antenoron herb, 15-60 parts of selfheal spike, 10-15 parts of rhizoma anemarrhenae, 15-20 parts of leech, 10-20 parts of plantain seed, 3-15 parts of rheum officinale, 10-20 parts of gentiana macrophylla and 8-15 parts of liquorice. The traditional Chinese medicinal composition used for treating the cirrhosis has the effects of eliminating or effectively controlling clinical symptoms of cirrhosis, promoting blood circulation and removing stasis, eliminating stagnation and stopping pain, soothing the liver and regulating vital energy, tonifying spleen and alleviating water retention, cirrhosis is treated by combining traditional Chinese medicines with western medicines clinically, the traditional Chinese medicines are used for carrying out dialectical treatment, the western medicines are used for carrying out symptomatic and supportive treatment, and obvious curative effect is obtained.

The invention discloses an application of MAGEA4 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The MAGEA4 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention discloses a medicine for treating rheumatoid arthritis and a preparation method thereof. The medicine comprises the ingredients of Chinese parsnip root, glabrous sarcandra herb, berba aristolochiae mollissimae, erycibe obtusifolia benth, Chinese Starjasmine Stem, tuber fleeceflower stem, Chinese Ivy Stem and the like which are called 'Three-Feng Four-Teng Soup'. The preparation method comprises the steps of cleaning, soaking, decocting and the like, all the raw materials are used in combination, and all the medicines cooperate in effects to effectively treat rheumatoid arthritis and effectively control the relapse of rheumatoid arthritis. The medicine for treating rheumatoid arthritis has the functions of suppressing fungi, dispelling wind to eliminate dampness, activating blood circulation to dissipate stasis, eliminating stagnation to stop pain, and clearing and activating the channels and collaterals, is high in efficiency and cure rate when used for treating rheumatoid arthritis, has no toxic and adverse effects and good safety, and is easy to prepare, low in cost and price and suitable for patients.

The invention discloses an application of MAGEB6 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The MAGEB6 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention belongs to the technical field of biomedicines, and in particular relates to a novel recombinant adenovirus vector bivalent living vaccine for resisting herpes progenitalis caused by herpes simplex virus type 2 infection. By a molecular biology technology, an expression kit for full-length sequences of genes containing herpes simplex virus type 2 glycoprotein B and glycoprotein D, and an expression kit for cell factor interleukin 2 are cloned to an adenovirus vector to form the vaccine. The vaccine is a replication-defective adenovirus vector living vaccine, only can express protective antigens without pathopoiesia after entering a human body, has high safety, and can simulate the wild herpes virus infection characteristic, effectively induce organism mucosal and humoral immune response and cell immune response, reduce the incidence rate of people, remove viruses which have infected people, and control the relapse and spread of herpes.

The invention discloses an application of DUSP21 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The DUSP21 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention discloses an artemether / benflumetol compound fat emulsion preparation which contains 0.01-1.5 percent by weight of artemether, 0.01-3.5 percent by weight of benflumetol, 10.0-30.0 percent by weight of injection oil, 0.6-30.0 percent by weight of emulsifier, 0-10 percent by weight of solubilizer, 00.01-5 percent by weight of co-emulsifier, 2.25-7 percent by weight of isoosmolar agent, 0.002-0.075 percent of antioxidant and the balance of injection water. The invention further discloses a preparation method as well as pharmacodynamics and safety elevation of the artemether / benflumetol compound fat emulsion preparation. The artemether / benflumetol compound fat emulsion preparation has the characteristics of good biocompatibility, high physical stability, good safety, high medicament-loading capacity and the like and is convenient to prepare. An in-vivo pharmacodynamic animal experiment proves that the artemether / benflumetol compound fat emulsion preparation has a remarkably killing role in plasmodium and can be used for effectively controlling the relapse of the plasmodium. Meanwhile, the artemether / benflumetol compound fat emulsion preparation can be used for providing nutritions required for the body of a patient suffering from malaria, improving the lymphocyte activity and assisting the patient in resisting malaria and getting recovery.

The invention relates to a medicine used for treating asthma, and especially relates to a traditional Chinese medicine used for treating asthma and prepared from plants and Chinese herbal medicines. Raw materials for preparing the traditional Chinese medicine used for treating asthma comprise 10-15g of Radix Peucedani, 3-9g of apricot kernel, 10-15g of mulberry leaf, 5-12g of Rhizoma Anemarrhenae, 5-12g of Radix Ophiopogonis, 13-19g of Radix Scutellariae, 13-19g of honeysuckle flower, 13-19g of Aster tataricus L. f., 13-19g of Fructus Aristolochiae and 3-9g of licorice root. The traditional Chinese medicine has synergistic medicine effects, has the efficacies of heat clearing, dampness drying, intense heat purging, detoxifying, lung heat clearing, qi depressing, phlegm reducing, cough relieving, spleen strengthening and vital qi benefiting, and has a substantial treatment effect on asthma induced by phlegm-fire attacking the lung, obstruction of stasis to long orifice, and impairment of purifying and descending function of the lung. The traditional Chinese medicine has a substantial curative effect, can alleviate symptoms during attack, and can remove fundamental causes and control recurrence through body resistance strengthening.

The invention discloses an application of LOC255313 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The LOC255313 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention provides a traditional Chinese medicine composition for treating liver cancer postoperative residual cancer or liver transplantation residual cancer, and relates to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition comprises the following raw materials in parts by weight of 10-15 parts of sunflower stem pith, 40-50 parts ofradix astragali, 6-9 parts of dried orange peel, 6-9 parts of Chinese thorowax, 4.5-6 parts of rhizoma ligustici wallichii, 4.5-6 parts of nutgrass galingale rhizomes, 4.5-6 parts of fructus aurantii, 4.5-6 parts of Chinese herbaceous peonies, 1.5-2 parts of licorice roots, 15-20 parts of common macrocarpium fruits, 15-20 parts of radix salviae miltiorrhizae, 10-15 parts of radix sophorae flavescentis and 15-20 parts of malaytea scurfpea fruits. The traditional Chinese medicine composition is significant in tumor resisting effects, can control growth and recurrence of the liver cancer postoperative residual cancer or liver transplantation residual cancer in a short time, can also obviously strengthen the constitutions of patients, can improve self disease-resistant repair capacity, can prolong the life of tumor patients, has favorable treatment effects on liver cancer at each stage, and is stable in medicine effects, rapid to absorb, high in speed of taking effect, reliable in treatment effects, short in treatment cycle and free from obvious toxic and side effects.

The invention discloses improved laparoscopic myomectomy. By the method of combining the uterine artery blockage with the pituitrin during operation, effects of reducing bleeding and lowering postoperative fibroid recurrence rate can be achieved in the laparoscopic myomectomy. According to clinical trial, research shows that after six months, sex hormone levels of a group A and a group B before and after operation are consistent in changes, no obvious difference is observed, and it shows that no obvious influence is caused on the endocrine function in ovaries after uterine artery blockage.

The invention provides mulberry and tuber fleeceflower root hair growing medicinal tea for treating alopecia and poliosis, and a preparation method and application thereof. The mulberry and tuber fleeceflower root hair growing medicinal tea is prepared from winter mulberry, tuber fleeceflower root, simpleleaf shrub chastetree fruit, skunk bugbane, yerbadetajo herba ecliptae and glossy privet fruit according to a certain weight part. The preparation method comprises the following steps of: packaging the simpleleaf shrub chastetree fruit and the glossy privet fruit with cloth, placing into a container, decocting by adding water, removing dregs and retaining the medicinal liquid; placing the winter mulberry, the tuber fleeceflower root, the skunk bugbane and theyerbadetajo herba ecliptae into the container, decocting by adding water, removing dregs and retaining the medicinal liquid; and finally, combining the medicinal liquid, filtering, adding crystal sugar and boiling to obtain brown medicinal liquid with a slightly sweet and slightly bitter taste, and bottling the brown medicinal liquid to obtain the mulberry and tuber fleeceflower root hair growing medicinal tea. The mulberry and tuber fleeceflower root hair growing medicinal tea has the advantages of scientific formula, obvious curative effect, convenience of use, low price, no toxic or side effect and the like; when using the product, a user drinks 100 milliliters of the tepid medicinal tea in the morning and at night each day; generally, after two weeks, pores are protruded and new hairs grow; furthermore, the mulberry and tuber fleeceflower root hair growing medicinal tea can blacken the hairs and relieve itching as well as control reappearance of alopecia and poliosis.

The invention discloses an application of CXorf41 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The CXorf41 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention discloses an application of CXorf41 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The CXorf41 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The invention relates to the field of traditional Chinese medicines, and in particular relates to an anti-cancer traditional Chinese medicinal composition, a preparation method and application thereof. The anti-cancer traditional Chinese medicinal composition consists of the following raw materials in parts by weight: 15-20 parts of dahurian rhododendron, 3-5 parts of gecko, 10-20 parts of rhizoma menispermi and 12-20 parts of fiveleaf akebia fruit, wherein the dahurian rhododendron is mixture of stems and leaves, the contents of female dahurian rhododendron and male dahurian rhododendron are the same in parts by weight. According to the anti-cancer traditional Chinese medicinal composition, the preparation method and application of the anti-cancer traditional Chinese medicinal composition in preparing anti-cancer medicines, the anti-cancer traditional Chinese medicinal composition acts on cancer cells by strengthening vital energy, eliminating stagnation and removing food retention, activating blood circulation, dredging channels and collaterals and the like through the synergic action of bulk traditional Chinese drugs in the prescription, so that growth and deterioration of early cancer cells can be effectively controlled, relapse or metastasis of cancer cells can be effectively controlled through surgical therapy, radiotherapy or chemical therapy, so that the effect of rescuing a patient or prolonging the life of the patient can be achieved.

The invention discloses a traditional Chinese medicine preparation for an external application capable of treating urticaria. The traditional Chinese medicine preparation is mainly prepared from the following raw materials in parts by weight: 10-15 parts of roots of kudzu vine, 7-13 parts of bermudagrass herb, 9-12 parts of large-leaved gentian, 11-15 parts of Chinese juniper leaves, 9-16 parts of waterlettuce herb, 7-16 parts of tuber fleeceflower stem, 9-15 parts of selago-like climbing fern herb, 8-15 parts of isodon amethystoides, 10-14 parts of affine cudweed, 12-16 parts of light wheat, 8-13 parts of buddha lamp stems and leaves, 10-16 parts of urtica cannabina, 12-15 parts of asiatic cudweed, 8-14 parts of common banana pericarp, 10-14 parts of clinopodium herb, 9-13 parts of pinus tabulaeformis carr, 6-10 parts of dodartia orientalis and 8-16 parts of eriocarpous glochidion leaves. The traditional Chinese medicine preparation is summarized by clinical practices for a plurality of years, and has the efficacies of dispelling wind, arresting itching, and clearing away heat and toxic materials, and is significant in curative effect.

The invention discloses a traditional Chinese medicine composition for treating gout as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 6 to 12 parts of radix angelicae sinensis, 3 to 10 parts of rhizoma chuanxiong, 15 to 30 parts of herba violae, 15 to 30 parts of herba taraxaci, 3 to9 parts of rhizoma corydalis decumbentis, 5 to 12 parts of radix achyranthis bidentatae, 10 to 15 parts of herba lysimachiae, 3-10 parts of notopterygium root, 3-10 parts of Terminalia chebula Retz and 1-3 parts of catechu. The traditional Chinese medicine composition can relieve red, swollen and hot pain in the acute attack period of gout, reduce the blood uric acid level, effectively control recurrence of gout and reduce the occurrence probability of other complications, and various adopted traditional Chinese medicine raw materials are simple and easy to obtain. The traditional Chinese medicine composition for treating acute attack of treatment gout can be obtained through simple extraction and concentration, the preparation process is simple, after different auxiliary materials are added, different dosage forms of agents for treating acute attack of treatment gout can be prepared, and the traditional Chinese medicine composition has important significance on acute attack of treatment gout.

The invention discloses a herpes simplex virus type 2 (HSV-2) genetic recombinant attenuated live vaccine and a preparation method thereof. US2, US3, US4 and US5 genes in a genome are knocked out. The method comprises the following steps of: separating and identifying vesicle liquid of a patient who suffers from oral herpes and genital herpes and has obvious vesicles to obtain wild type HSV-1 and HSV-2; performing amplifying culture, and extracting a virus complete genome; transfecting Vero cells by using a shuttle vector containing a fluorescent expressed gene and 700bp to 2,000bp homologous flanking sequences on the left and right sides of an HSV gene which is prepared to be knocked out; and picking recombinant virus out under a fluorescent microscope by using one or more fluorescent protein genes as markers, and performing plaque purification to obtain the needed recombinant attenuated live vaccine. The vaccine effectively induces mucosal and humoral immune response of organisms, so that the morbidity of people is reduced; and cellular immune response is excited, so that the infected virus can be cleared, and the relapse and spreading of herpes are controlled.

The invention relates to an anti-cancer drug composition. The anti-cancer drug composition comprises active ingredients: NDV (Newcastle Disease Virus) particles and NA (neuraminidase), and the activity of NDV is 10<6>-10<7> PFU / ml, and the activity of NA is 0.01-0.02u / ml. The anti-cancer drug composition has the advantages of wide anti-tumor spectrum, and obvious therapeutic effect, no obvious toxic or side effect, immunization, and direct killing effect on cancer cells. The invention further provides a preparation method of the anti-cancer drug composition.

The invention discloses an application of MAGEA10 gene which is used for preparing products for diagnosing liver cancer and medicines for treating the cancer. The MAGEA10 gene of the invention can be used as the peculiar marker gene for diagnosing liver cancer, facilitates the diagnosis on the liver cancer to be more accurate and rapid and provides new therapeutic targets and effective medicines for preventing and treating liver cancer.

The present invention relates to a pharmaceutical composition comprising at least one first active therapeutic substance selected from the group consisting of carveol, thymol, eugenol, camphor, carvacrol, α-ionone, β-ionone and isomers, derivatives and mixtures thereof; and comprising at least one second active therapeutic substance which is an antiparasitic drug, in particular an antimalarial drug . The invention is applied in the pharmaceutical field.

The invention provides a traditional Chinese medicine composition for auxiliary treatment of small cell lung cancer, and relates to the technicalfield of traditional Chinese medicine compositions. Thetraditional Chinese composition is prepared from the following raw materials in parts by weight: 10-15 parts of sunflower stem pith, 10-15 parts of radix astragali, 10-15 parts of gapplanatum, 40-50parts of black bean peel, 40-50 parts of herba rabdosiae, 25-30 parts of asiatic pennywort herb, 10-15 parts of herba hedyotidis diffusae and 2.5-5 parts of radix glycyrrhizae. The effect of the traditional Chinese medicine composition on the auxiliary standardchemotherapy treatment of the small cell lung cancer in extensive period is significant, the growth of tumor can be controlledwith the chemotherapy, meanwhile the traditional Chinese medicine composition is further used for strengthening the physique of patients in the operation period, the disease-resistant and repair ability of the patients with the small cell lung cancer is improved, thus the life of the patients with tumor is prolonged, a certain therapeutic effect on the small cell lung cancer in various periods is achieved, thepesticide effect is stable, absorption is quick, effect is achieved quickly, curative effect is reliable, the treatment cycle is short, and obvious side effects are avoided.

The invention provides a recombined attenuated live vaccine for preventing and treating I-type or II-type infection of herpes simplex virus and preparation method thereof. The recombined attenuated live vaccine is characterized by omitting the UL43, UL44, UL45, UL46 and UL47 genes in the genome thereof; the method comprises the steps of: separating and identifying a wild-type herpes simplex virus; carrying out enlarged cultivation, extracting the complete genome of the virus, and designing a primer to amplify a homologous flanking sequence formulating the omitted gene segment; cloning the homologous flanking sequence and a fluorescent protein gene to a pShuttle-CMV carrier to carry out homologous recombination; selecting the recombined virus by taking the fluorescent protein gene as a mark; and carrying out plaque purification to obtain the gene-recombined attenuated live vaccine of the herpes simplex virus. The attenuated live vaccine prepared by the invention undergoes gene engineering recombination so that toxicity returning is not easy to happen, and the other biological characteristics of the attenuated live vaccine are similar to those of the wild-type herpes simplex virus.