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A kind of traditional Chinese medicine composition and its preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation, can solve problems such as prevention and control of vascular plaque atherosclerosis, etc.

Active Publication Date: 2022-07-26
BEIJING REGEN PHARMATECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, at present, there are no drugs based on traditional Chinese natural medicines to prevent and control vascular plaque formation and treat atherosclerosis.

Method used

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  • A kind of traditional Chinese medicine composition and its preparation method and application
  • A kind of traditional Chinese medicine composition and its preparation method and application
  • A kind of traditional Chinese medicine composition and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Embodiment 1: the preparation of Chinese medicine composition of the present invention

Embodiment 1-1

[0069] Weigh the following raw materials: Bupleurum 25g, Citrus aurantium 15g, raw rhubarb 10g, Scutellaria baicalensis 6g, white peony 10g, dried ginger 6g, leech 10g, licorice 10g, Codonopsis 10g, Atractylodes 10g, Pinellia 15g, raw oyster 30g. Boil and lift twice in an airtight container, add 8 times the amount of water for the first time, and keep the temperature at 80 degrees Celsius for 60 minutes after boiling to obtain a decoction liquid; add 6 times the amount of water for the second time, and keep the water at 80 degrees Celsius for 60 minutes after boiling to obtain the second decoction Cooking liquid; combine the secondary decoction liquid, filter, and combine the filtrate. Concentrate under reduced pressure (-0.05Mpa, 60°C) to a relative density of 1.05-1.15 (60°C), freeze-dried under reduced pressure to obtain dry extract powder A, and the extract yield is 25% of the crude drug amount.

[0070] β-cyclodextrin was added to the obtained dry extract powder A at a ra...

Embodiment 1-2

[0072] Weigh the following APIs: Bupleurum 25g, Citrus aurantium 15g, raw rhubarb 10g, Scutellaria baicalensis 6g, Radix Paeoniae Alba 10g, dried ginger 6g, leech 10g, licorice 10g, Codonopsis 10g, Atractylodes Rhizoma 10g, Pinellia 15g, cook in an airtight container Twice, add 8 times the amount of water for the first time, and keep the temperature at 80 degrees Celsius for 60 minutes after boiling to obtain a decoction liquid; add 6 times the amount of water for the second time, and keep the water at 80 degrees Celsius for 60 minutes after boiling to obtain the second decoction liquid; The secondary decoction liquid was filtered, and the filtrate was combined. Concentrate under reduced pressure (-0.05Mpa, 60°C) to a relative density of 1.05-1.15 (60°C), freeze-dried under reduced pressure to obtain dry extract powder B, and the extraction rate of the extract is 25% of the crude drug amount.

[0073] β-cyclodextrin was added to the obtained dry extract powder B at a ratio of ...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition of the present invention comprises the following raw materials by weight: 10-35 parts of Bupleurum, 5-25 parts of Citrus aurantium, 3-20 parts of raw rhubarb, 3-20 parts of Scutellaria baicalensis, 3-20 parts of white peony root, Ginger 3-15 parts, leeches 5-20 parts, licorice 3-20 parts, Codonopsis 3-20 parts, Atractylodes 3-20 parts, Pinellia 3-25 parts. The traditional Chinese medicine composition of the present invention has excellent effects of reducing blood lipids, cholesterol, especially blood triglyceride; the traditional Chinese medicine composition of the present invention also has the functions of slowing down the formation of atherosclerotic plaques, removing atherosclerotic plaques, preventing and treating arteries Good effect on atherosclerosis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition and a preparation method thereof, and the preparation of the traditional Chinese medicine composition for preventing or treating elevated blood lipids, elevated triglycerides, elevated cholesterol, hyperlipidemia, atherosclerosis Application of sclerotherapy. Background technique [0002] Blood lipids are the general term for various lipids in the blood. The most important ones are cholesterol and triglycerides. Triglycerides are also called neutral fats. Other important lipids include lipoproteins, including low-density lipoproteins and high-density lipoproteins. density lipoprotein. The average blood cholesterol content of healthy people is between 2.8 and 5.17 mmol / L, and the average blood triglyceride content is between 0.56 and 1.7 mmol / L. Whether it is elevated cholesterol, elevated triglycerides, or both, it is collecti...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P3/06A61P9/10A61P3/00A61K35/618A61K35/62
CPCA61K36/233A61K36/752A61K36/708A61K36/539A61K36/71A61K36/65A61K36/9068A61K35/62A61K36/484A61K36/344A61K36/284A61K36/8888A61K35/618A61K36/899A61K36/062A61P3/06A61P9/10A61P3/00A61K2236/19A61K2236/331A61K2236/39A61K2300/00A61K9/1652A61K2236/00A61K36/53A61K36/54A61K36/69
Inventor 解渤任雪峰
Owner BEIJING REGEN PHARMATECH CO LTD
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