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Traditional Chinese medicine composition for treating acute and chronic hepatitis and hepatic cirrhosis as well as preparation method and quality detection method thereof

A combination, acute and chronic technology, applied in the field of medicine, can solve the problems of production equipment, high process conditions, long treatment cycle, palliative treatment, not the root cause, etc., to achieve the effect of ensuring quality and effectiveness, simple eating method, and effective identification

Pending Publication Date: 2021-11-26
乐泰药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this invention, the dosage form is traditional Chinese medicine injection, which has higher requirements on production equipment and process conditions, and higher cost
Moreover, Kuhuang injection can only reduce jaundice, and it is used as supportive therapy and symptomatic treatment. It treats the symptoms but not the root cause, and the treatment cycle is long, the cost is high, the side effects are large, and the cure rate is low.

Method used

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  • Traditional Chinese medicine composition for treating acute and chronic hepatitis and hepatic cirrhosis as well as preparation method and quality detection method thereof
  • Traditional Chinese medicine composition for treating acute and chronic hepatitis and hepatic cirrhosis as well as preparation method and quality detection method thereof

Examples

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Effect test

specific Embodiment 1

[0057] The present embodiment provides an acute and chronic hepatitis, cirrhosis Chinese medicine prescription treatment. Parts by weight of the following constituents: 100 parts capillaris, Berberis root 60 parts, 50 parts of bupleurum, dandelion 50 parts, 20 parts of Scutellaria, comfrey 5 parts, 5 parts of starch.

[0058] The method of treating acute and chronic hepatitis, liver cirrhosis Chinese medicine preparation, comprising the steps of:

[0059] 1. Weigh the ingredients: the formulation according to the amount of each medicine Pieces weighed and set aside.

[0060] 2. Lithospermum process: 2 Lithospermum process: The pulverized comfrey, ultrasonic assisted ethanol extraction, the extraction agent is 60-80% ethanol, solid-liquid ratio of 5-10 times, 30-50 deg.] C extraction temperature, ultrasonic 20-50kHz frequency, time 0.5-1h, filtered, dregs backup, recovering ethanol filtrate was concentrated, added 2% NaOH, filtered, the precipitate was dried and concentrated to giv...

specific Embodiment 2

[0066] The present embodiment provides an acute and chronic hepatitis, cirrhosis Chinese medicine prescription treatment. Parts by weight of the following constituents: 150 parts capillaris, Berberis root 20 parts, 30 parts bupleurum, dandelion 50 parts, 20 parts of Scutellaria, comfrey 5 parts, 5 parts of starch.

[0067] The method of treating acute and chronic hepatitis, liver cirrhosis Chinese medicine preparation, comprising the steps of:

[0068] 1. Weigh the ingredients: the formulation according to the amount of each medicine Pieces weighed and set aside.

[0069] 2. Lithospermum process: The pulverized comfrey, ultrasonic assisted ethanol extraction, the extractant is 80% ethanol, solid-liquid ratio of 5 times, the extraction temperature 30 ℃, ultrasonic frequency 20kHz, time 0.5h, filtered, spare dregs , recovering ethanol filtrate was concentrated, added 2% NaOH, filtered, the precipitate was dried and concentrated to give a crude total alkaloid extract is removed. The ...

specific Embodiment 3

[0075] The present embodiment provides an acute and chronic hepatitis, cirrhosis Chinese medicine prescription treatment. Parts by weight of the following constituents: 80 parts capillaris, Berberis root 80 parts, 50 parts of bupleurum, dandelion 40 parts, 25 parts of Scutellaria, comfrey 6 parts, 5 parts of starch.

[0076] The method of treating acute and chronic hepatitis, liver cirrhosis Chinese medicine preparation, comprising the steps of:

[0077] 1. Weigh the ingredients: the formulation according to the amount of each medicine Pieces weighed and set aside.

[0078] 2. Lithospermum process: The pulverized comfrey, ultrasonic assisted ethanol extraction, the extraction agent is 70% ethanol, solid-liquid ratio was 8 times, extraction temperature 40 ℃, 30kHz ultrasonic frequency, time 40min, filtered, the dregs standby, recovering ethanol filtrate was concentrated, adding an amount 2% NaOH, filtered, the precipitate was dried and concentrated to give a crude total alkaloid ex...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating acute and chronic hepatitis and hepatic cirrhosis as well as a preparation method and a quality detection method thereof, and relates to the field of medicines. The traditional Chinese medicine composition with effects of clearing liver and promoting diuresis is prepared by taking herba artemisiae scopariae, berberis root, radix bupleuri, herba taraxaci, radix scutellariae and radix arnebiae seu lithospermi as raw materials, and used for treating acute and chronic hepatitis, initial hepatic cirrhosis and edema. The preparation method comprises the following steps: firstly treating radix arnebiae seu lithospermi, then extracting and concentrating berberis root, herba artemisiae scopariae, radix bupleuri, radix scutellariae and herba taraxaci and finally conducting mixing, drying, crushing, sieving and granulating. According to the invention, content of baicalin in the traditional Chinese medicine composition is measured. The invention also provides a traditional Chinese medicine preparation identification method for herba artemisiae scopariae and radix scutellariae. The traditional Chinese medicine composition has good curative effects on acute and chronic hepatitis, initial hepatic cirrhosis, edema, liver injury, etc. The invention is applied to the field of medicines.

Description

Technical field [0001] The present invention relates to the field of medical technology, and more particularly to a treatment of acute and chronic hepatitis, cirrhosis traditional Chinese medicine compositions and preparation methods thereof. Background technique [0002] Hepatitis, usually refers to a variety of pathogenic factors such as viruses, bacteria, parasites, chemical poisons, drugs, poisons, alcohol, etc., which violents the liver, so that the liver is damaged, the function of the liver is damaged, causing a series of body Unwell symptoms, and abnormal liver function indicators. Hepatitis is that hepatocyte necrosis due to various reasons, abnormal liver function can be divided into acute hepatitis and chronic hepatitis, mainly different from the causes of pathogenesis. [0003] Acute hepatitis means that hepatitis has caused liver disease due to hepatitis viruses, the general course of disease is no more than 6 months. Acute hepatitis is mainly divided into acute vira...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P1/16A61P7/10G01N30/02G01N30/06G01N30/14G01N30/90G01N30/95
Inventor 郎伟君
Owner 乐泰药业有限公司
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