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Application of gastrodia elata and uncaria beverage in prevention and treatment of alopecia seborrhoeica and preparation method of gastrodia elata and uncaria beverage extract

A technology of Tianma Gouteng Decoction and seborrheic alopecia, applied to the preparation of Tianma Gouteng Decoction extract, the application field of Tianma Gouteng Decoction in the prevention and treatment of seborrheic alopecia

Active Publication Date: 2022-01-07
ZUNYI MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the published literature, although the extraction of Tianma Gouteng Decoction is disclosed, most of them focus on the optimization of the extraction process of gastrodin and polysaccharides, and the obtained gastrodin and polysaccharides are also used to prevent and treat hypertension

Method used

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  • Application of gastrodia elata and uncaria beverage in prevention and treatment of alopecia seborrhoeica and preparation method of gastrodia elata and uncaria beverage extract
  • Application of gastrodia elata and uncaria beverage in prevention and treatment of alopecia seborrhoeica and preparation method of gastrodia elata and uncaria beverage extract
  • Application of gastrodia elata and uncaria beverage in prevention and treatment of alopecia seborrhoeica and preparation method of gastrodia elata and uncaria beverage extract

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preparation example Construction

[0033] In the present invention, the preparation method of the Tianma Gouteng drink extract preferably includes the following steps:

[0034] mixing Tianma Gouteng decoction and ethanol solution, performing leaching and first ultrasonic extraction in sequence to obtain the initial extraction liquid and the initial extraction residue;

[0035] The primary extraction residue is mixed with the ethanol solution, and a second ultrasonic extraction is performed to obtain a second filtrate and a second filter residue;

[0036] performing water extraction on the second filter residue to obtain a water extract;

[0037] The primary extract, the second filtrate and the water extract are respectively concentrated, mixed, and freeze-dried to obtain the Tianma Gouteng drink extract.

[0038] The invention mixes Tianma Gouteng decoction and ethanol solution, sequentially carries out leaching and first ultrasonic extraction, and obtains initial extraction liquid and initial extraction resid...

Embodiment 1

[0066] Weigh Gastrodia elata (9g), Uncaria (12g), Cassia (18g), Gardenia (9g), Scutellaria baicalensis (9g), Eucommia ulmoides (9g), Motherwort (9g), Sangji (9g), and Caulis japonica (9g), Zhu Fushen (9g) and Sichuan Achyranthes bidentata (12g), mix the above mixture with an ethanol solution with a volume concentration of 90% according to the ratio of 1g: 20mL, and extract at room temperature for 12h; then at room temperature, 80kHz Carry out the first ultrasonic extraction for 30 minutes, and centrifuge to obtain the initial extraction liquid and the initial extraction residue; the initial extraction liquid is concentrated to 0.5% of the volume of the original liquid by rotary evaporation at 40-50 ° C and 109 r / min to obtain the initial extract;

[0067] The initial extraction residue and the ethanol solution with a volume concentration of 90% were mixed according to the ratio of 1g: 20mL, and the second ultrasonic extraction was carried out at room temperature and 80kHz for 1...

Embodiment 2

[0071] The extraction operation in Example 1 was repeated several times to obtain the extract of Tianma Gouteng Decoction, and the extraction rate was 17-21%.

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Abstract

The invention belongs to the technical field of traditional Chinese medicine extracts, and provides application of a gastrodia elata and uncaria beverage in preventing and treating alopecia seborrhoeica and a preparation method of a gastrodia elata and uncaria beverage extract. The invention provides application of the gastrodia elata and uncaria beverage in preventing and treating alopecia seborrhoeica. The gastrodia elata and uncaria beverage is a traditional Chinese medicine composition containing gastrodia elata, uncaria, concha haliotidis, cape jasmine, scutellaria baicalensis, eucommia ulmoides, leonurus, herba taxilli, tuber fleeceflower stem, cinnabar poria with hostwood and radix cyathulae in a mass ratio of 9: 12: 18: 9: 9: 9: 9: 9: 9: 9: 12. The gastrodia elata in the gastrodia elata and uncaria beverage is sweet, mild and moist in quality, is specially applied to the liver channel, is called 'long-term consumption for tonifying qi and nourishing yin and strengthening body', has the function of calming liver wind, and has the Chinese name of 'Dingfencao'. The uncaria is sweet and slightly cold, belongs to the liver and pericardium, and is mainly used for extinguishing wind, relieving convulsion and calming liver wind. The gastrodia elata and uncaria have the effects of dispelling wind, eliminating dampness, stopping alopecia and strengthening hair.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extracts, in particular to the application of Tianma Gouteng Decoction in preventing and treating seborrheic alopecia and the preparation method of Tianma Gouteng Decoction extract. Background technique [0002] Gastrodia Gouteng Decoction comes from "New Means of Treatment of Miscellaneous Diseases", composed of Gastrodia elata, Uncaria, Shicaiming, Gardenia, Scutellaria, Achyranthes bidentata, Eucommia, Kuncao, Sangji, Yejiaoteng and Fushen. Wind, clearing away heat and calming the nerves. This product mainly treats headache, dizziness and insomnia caused by liver wind disturbance. The traditional decoction technique of Tianma Gouteng Decoction has a good effect on the treatment of high blood pressure. In the published literature, although the extraction of Tianma Gouteng Decoction is disclosed, most of them focus on the optimization of the extraction process of gastrodin ...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P17/08A61P17/14A61K35/618
CPCA61K36/8988A61K36/74A61K35/618A61K36/744A61K36/539A61K36/46A61K36/533A61K36/185A61K36/704A61K36/076A61K36/21A61P17/14A61P17/08A61K2236/333A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 李征张彦彦李晶洁龙芸鸾杜番攀王无忌
Owner ZUNYI MEDICAL UNIVERSITY
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