16 results about "Tianmagouteng" patented technology

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating cervical spondylosis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following bulk drugs by weight: 45 to 55 g of pinellia ternate, 45 to 55 g of bighead atractylodes rhizome, 45 to 55 g of gastrodia elata, 45 to 55 g of uncaria, 45 to 55 g of poria cocos, 95 to 105 g of tuber fleeceflower stem, 95 to 105 g of red sage root, 45 to 55 g of Chinese angelica, 45 to 55 g of ligusticum wallichii, 45 to 55 g of peach kernel, 45 to 55 g of safflower, 45 to 55 g of red peony root, 45 to 55 g of notopterygium root, 45 to 55 g of turmeric, 25 to 35 g of pseudo-ginseng, 25 to 35 g of leech, 95 to 105 g of root of kudzu vine, 95 to 105 g of ginkgo leaf, 95 to 105 g of clematis root, 45 to 55 g of earthworm, 45 to 55 g of drynaria rhizome, the traditional Chinese medicine is quick in effect and high in curative effect, and the clinical total effective rate of the traditional Chinese medicine is 100% according to clinical practice statistics.

The invention belongs to the field of pharmaceutical analysis, and particularly relates to a method for establishing a traditional Chinese medicine fingerprint spectrum of a gastrodia elata and uncaria decoction. The method is realized by the following steps: firstly, preparing a reference substance solution and a test solution, then detecting by adopting a high performance liquid chromatography, and establishing a fingerprint spectrum. According to the method provided by the invention, by reasonably selecting the components of the reference substance and adopting a multi-wavelength method according to the maximum absorption wavelength of the components, the change of the component amount between the samples can be effectively represented, so that the quality of the samples is more accurately judged; the invention further provides a screening and optimizing method for the preparation method of the gastrodia elata and uncaria decoction, the prepared method is good in repeatability and stability, the quality of the gastrodia elata and uncaria decoction can be monitored more comprehensively, and the method provides valuable reference for quality evaluation and standardization of traditional Chinese medicine decoction.

The invention relates to the technical field of traditional Chinese medicine formulas for treating hypertension, in particular to a traditional Chinese medicine compound preparation for treating liver-yang hyperactivity type hypertension or yin deficiency and yang hyperactivity type hypertension as well as a preparation method and application of the traditional Chinese medicine compound preparation for treating liver-yang hyperactivity type hypertension or yin deficiency and yang hyperactivity type hypertension. The medicinal materials comprise gastrodia elata, uncaria, fried stiff silkworm, cornu bubali, concha haliotidis, selfheal, radix cyathulae, salted eucommia ulmoides, salted semen plantaginis and fried spina date seed. The preparation method comprises the following steps: decocting a required amount of buffalo horn with water to obtain a buffalo horn decoction; soaking other medicinal materials except the uncaria in water, decocting the soaked medicinal materials and the cornu bubali decoction for two to three times, adding the uncaria into the decoction five to seven minutes before the last decoction, and combining the decoction to obtain the traditional Chinese medicine compound preparation. The traditional Chinese medicine compound preparation disclosed by the invention has a blood pressure lowering effect on people with different symptoms of hypertension, is stable in blood pressure lowering and reliable in effect, and has the effects of nourishing yin, suppressing yang, calming the liver and calming the heart.

The invention relates to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine for treating hypertension, which is prepared from the following raw medicinal materials by weight: 14-16 g of gastrodia elata, 12-18 g of uncaria, 14-16 g of concha haliotidis, 8-12 g of eucommia ulmoides, 14-16 g of achyranthes bidentata, 8-12 g of parasitic loranthus, 6-14 g of cape jasmine, 8-12 g of scutellaria baicalensis, 6-14 g of motherwort, 14-16 g of poria with hostwood, 8-12 g of tuber fleeceflower stem, 25-35 g of salvia miltiorrhiza, 14-16 g of ligusticum wallichii and 12-18 g of chrysanthemum. The traditional Chinese medicine composition is scientific and reasonable in traditional Chinese medicine formula, can effectively regulate the body function of a patient and stabilize the blood pressure through the synergistic effect of the medicinal materials, has a remarkable curative effect after being taken persistently, adopts natural traditional Chinese medicinal materials, is small in side effect on a human body, avoids adverse reaction, is relatively low in cost, and relieves the economic burden of the patient.

The invention relates to a composition for reducing blood fat and blood sugar and improving blood pressure and application thereof, and belongs to the technical field of traditional Chinese medicines. The technical problems that in the prior art, the technology of thirst quenching decoction and gastrodia elata and uncaria decoction prescriptions is backward, and the dosage is large are solved. The composition consists of the following traditional Chinese medicine extracts in parts by mass: 3-9 parts of a traditional Chinese medicine extract A, 2-4 parts of a traditional Chinese medicine extract B, 5-7 parts of a traditional Chinese medicine extract C and 2-6 parts of a traditional Chinese medicine extract D, according to the invention, classic prescriptions of diabetes decoction and gastrodia elata and uncaria drink are applied, effective components are extracted and separated through modern science and technology, effective extracts are obtained, and the curative effect is exerted through a corresponding proportion. Pharmacodynamic research shows that the traditional Chinese medicine composition can achieve the effects of reducing blood fat and blood sugar and improving blood pressure through the effects of clearing stomach heat and nourishing kidney yin. And the related process is advanced, and the dose is not large.

The application discloses application of Dingxuan Granules in preparation of medicines for treating early kidney damage caused by hypertension of the type of yin deficiency and yang hyperactivity, and the Dingxuan Granules are prepared from radix rehmanniae, lycium barbarum, gastrodia, uncaria, wine salvia miltiorrhiza, alisma, motherwort and achyranthes bidentata. The Dingxuan Granules have the effects of tonifying liver and kidney, calming liver wind and promoting water and descending qi, and are suitable for people with early kidney damage caused by hypertension.

A traditional Chinese medicine for treating hypertension liver yang hyperactivity syndrome comprises the following raw materials by weight: 18-23g of Tribulus terrestris, 18-23g of Bidens pilosa, 18-23g of Astragalus membranaceus, 10-14g of Plantago seed, 8-11g of Chrysanthemum, 8-11g of Cibotium barometz, 8-11g of Gastrodia elata, 8-11g of Uncaria rhynchophylla, 8-12g of Semen Cassiae, 8-12g of Pheretima and 13-17g of Pueraria root; the raw materials are mixed, soaked in water and decocted twice, firstly adding water 8 times of the total weight thereof and decocting for 1 hour to obtain a first decoction, secondly adding water 6 times of the total weight thereof and decocting for 0.5 hour to obtain a second decoction, combining the two decoctions, filtering and concentrating to 1 / 5 of the total volume to obtain the traditional Chinese medicine; the traditional Chinese medicine has abundant raw materials, simple preparation method, easy production and convenient administration, and has obvious effect in treating hypertension liver yang hyperactivity syndrome, good safety and huge social and economic benefits.

The invention belongs to the field of traditional Chinese medicines, discloses a novel application of a gastrodia elata dizziness-relieving preparation, and particularly relates to an application of the gastrodia elata dizziness-relieving preparation in medicines for preventing and treating Parkinson's disease and motor complications thereof. The gastrodia elata dizziness relieving preparation is prepared from 12 raw medicinal materials including gastrodia elata, uncaria, rhizoma alismatis, pinellia ternate, bighead atractylodes rhizome, poria cocos, radix paeoniae alba, caulis bambusae in taeniam, ligusticum wallichii, liquorice, pericarpium citri reticulatae and ginger. Modern pharmacodynamic test research shows that the gastrodia elata dizziness relieving preparation can regulate expression of alpha-synuclein, LC3B and Beclin1 of a Parkinson's disease model rat group, and has a neuroprotective effect on the model rats; the gastrodia elata Jiangning granules have obvious effects of improving behavioristics of Parkinson's disease model mice, and have good prevention and treatment effects on motion fluctuation and dyskinesia of Parkinson's disease and complications of Parkinson's disease.

This invention relates to the field of traditional Chinese medicine (TCM) technology, and discloses a TCM composition for treating obesity-related hypertension and its preparation method. The composition is made from white ginseng, gynostemma pentaphyllum, Eucommia ulmoides, kudzu root, Atractylodes macrocephala, hawthorn, Alisma plantago-aquatica, Euonymus alatus, Gastrodia elata, Uncaria rhynchophylla, peppermint, and Rhodiola rosea. The preparation process includes a compound enzymatic hydrolysis pretreatment, utilizing cellulase and pectinase to synergistically disrupt cell walls, combined with dual extraction steps of water extraction and alcohol extraction to selectively dissolve components of different polarities. Pharmaceutical excipients are then added to prepare concentrated pills, granules, or tablets. This composition has the effects of invigorating the spleen and replenishing qi, resolving phlegm and eliminating turbidity, and calming the liver and suppressing yang. Through multi-target synergistic action, it achieves simultaneous intervention on blood pressure levels and lipid metabolism, effectively improving metabolic abnormalities in obese patients. The process of this invention reduces mass transfer resistance, increases the transfer rate of total saponins and flavonoids, and results in a product with uniform and stable quality, suitable for large-scale production.

The invention provides a traditional Chinese medicine composition for resisting Alzheimer's disease as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following active ingredients in parts by weight: 6-50 parts of gastrodia elata, 6-50 parts of uncaria rhynchophylla, 9-60 parts of concha haliotidis, 6-50 parts of prepared rehmannia root, 6-50 parts of radix cyathulae, 3-30 parts of semen raphani, 3-30 parts of eucommia ulmoides, 3-30 parts of parasitic loranthus, 3-30 parts of scutellaria baicalensis, 3-30 parts of herba lycopi, 3-30 parts of vine of multiflower knotweed and 3-30 parts of cinnabar root poria. The raw materials of the medicine are common, the preparation method is simple and easy to operate, the medicine has wide application value, after oral administration of the medicine, cognitive impairment of a transgenic mouse model of the Alzheimer's disease can be obviously improved, deposition of age pigment in brain tissue is reduced, meanwhile, the number of activated microglia and astroglia in the brain tissue is reduced, and the treatment effect of the Alzheimer's disease is improved. The compound inhibits the formation of A beta in brain tissues, and has a new application of anti-Alzheimer's disease drugs.

The application belongs to the field of pharmaceutical analysis, and particularly relates to a method for establishing a traditional Chinese medicine fingerprint spectrum of Gastrodia and Uncaria Decoction. The method is realized through the following steps: firstly, preparing a reference solution and a sample solution, and then detecting by using high performance liquid chromatography to establish the fingerprint spectrum. The method provided by the application can effectively represent the change of the component quantity among samples by reasonably selecting the reference component and using the multi-wavelength method according to the maximum absorption wavelength of the component, so that the quality of the sample can be more accurately judged. The application further provides a preparation method screening and optimization method of Gastrodia and Uncaria Decoction, the prepared method has good repeatability and stability, and can more comprehensively monitor the quality of Gastrodia and Uncaria Decoction, and the method provides a valuable reference for the quality evaluation and standardization of traditional Chinese medicine decoction.

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases, which consists of feverfew, ligusticum chuanxiong hort, gastrodia elata, uncaria rhynchophylla, edible tulip, sculellaria barbata, oldenlandia diffusa, trichosanthes kirilowii maxim, allium macrostemon, fructus aurantii, rhizoma clematidis, helichthyos, fructus amomi, rhizoma corydalis, szechwan chinaberry fruit, mangnolia officinalis, rhizoma cyperi, costus root, charred triplet, dandelion, bunge corydalis herb, isatis root, rheum officinale and mirabilite. The traditional Chinese medicine has the advantages that 1, qi and blood of a human body can be dredged and detoxified from top to bottom, and the qi and blood can be drained; 2, pills are convenient to take and carry;

1. Name of the product in this design: Traditional Chinese Medicine Decoction Bag (Gastrodia and Uncaria Decoction). 2. Purpose of this design: For use in bags for traditional Chinese medicine decoctions. 3. The key design feature of this product is its pattern. 4. The image or photograph that best illustrates the design's key points: the front view. 5. This design is for a thin product, therefore the left view, right view, top view, and bottom view are omitted.

The invention discloses a method for determining the content of caulis polygoni multiflori in a traditional Chinese medicine preparation, and relates to the field of detection methods of high performance liquid chromatography, the method adopts high performance liquid chromatography for determination, the high performance liquid chromatography comprises selection of a reference substance, a filler and a mobile phase, the reference substance comprises 2, 3, 5, 6-tetramethyl-3-piperidine-2-one, and the filler comprises 2, 3, 5, 6-tetramethyl-3-piperidine-2-one. The mobile phase is prepared from 4, 4 '-tetrahydroxystilbene-2-O-beta-D-glucoside, the filler is prepared from octadecylsilane chemically bonded silica, the mobile phase is prepared from acetonitrile and water, and the volume ratio of the acetonitrile to the water is (14-25): (75-95). By optimizing chromatographic conditions and chromatographic detection conditions, such as composition of a mobile phase and selection of a reference substance and a filling agent, the detection efficiency of 2, 3, 5, 6, 7-tetramethyl-4-piperidine in the gastrodia elata and uncaria granules is improved, and the quality of the gastrodia elata and uncaria granules is improved. According to the present invention, with the method, the THSG concentration in the sample can be accurately determined according to the precision and the sensitivity of the THSG content in the sample, such that the reliable result can be obtained even at the low concentration level.

The invention belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a traditional Chinese medicine composition for treating hypertension and a preparation method and application thereof, and the traditional Chinese medicine composition comprises radix rehmanniae, radix cyathulae, radix salviae miltiorrhizae, ligusticum wallichii, eucommia ulmoides, radix puerariae, caulis spatholobi, gastrodia elata, uncaria rhynchophylla, concha haliotidis, selfheal, angelica sinensis, radix paeoniae rubra, fructus gardeniae, scutellaria baicalensis, peach kernels and safflower carthamus. The radix cyathulae is used for guiding downward flow of blood and tonifying liver and kidney, the radix salviae miltiorrhizae is used for promoting blood circulation to remove blood stasis, the rhizoma chuanxiong is used for promoting blood circulation to promote qi, dispelling wind and relieving pain, the cortex eucommiae is used for tonifying liver and kidney and strengthening muscles and bones, the radix puerariae is used for relieving muscles and dispelling wind and clearing and activating the channels and collaterals, the caulis spatholobi is used for promoting blood circulation to remove meridian obstruction and enriching blood, the rhizoma gastrodiae is used for stabilizing liver yang, calming endogenous wind and relieving spasm, and the uncaria is used for stabilizing liver yang, reducing blood pressure and regulating and controlling heart rate; the common peony root has the effects of clearing heat and cooling blood, the cape jasmine has the effects of clearing heat and cooling blood, the baical skullcap root has the effects of clearing heat and drying dampness, and the peach kernel and the safflower have the effects of promoting blood circulation and removing blood stasis, and all the medicines supplement one another to jointly play the roles of reducing blood pressure, improving circulation and protecting organs such as heart, brain and kidney.

A composition for treating mitochondrial dysfunction in Parkinson's disease, comprising an extract; the extract is extracted from a raw material drug; the raw material drug comprises Rehmannia glutinosa, Fructus Corni, Lycium barbarum, Cistanche deserticola, Morinda officinalis, Polygala tenuifolia, and Acorus tatarinowii. In the raw material drug, the mass ratio of Rehmannia glutinosa, Fructus Corni, Lycium barbarum, Cistanche deserticola, Morinda officinalis, Polygala tenuifolia, and Acorus tatarinowii is 1:1:1:1:1:0.5:0.5. Also included: the raw material drug further comprises Gastrodia elata: Uncaria rhynchophylla. In the raw material drug, the mass ratio of Rehmannia glutinosa, Fructus Corni, Lycium barbarum, Cistanche deserticola, Morinda officinalis, Polygala tenuifolia, Acorus tatarinowii, Gastrodia elata, and Uncaria rhynchophylla is equal to 1:1:1:1:1:0.5:0.5:0.5:1.