A bioreactor constant temperature system

Abstract

The present invention provides a bioreactor constant temperature system, the main point of the technical solution is that the bioreactor constant temperature system includes a first constant temperature device, the first constant temperature device includes a base, a sleeve and a first constant temperature adjustment module, the sleeve is installed on the base, And the inner side of the sleeve and the base jointly form an accommodating space with an upper opening and a bioreactor can be placed, the first constant temperature adjustment module includes at least one Peltier, at least one Peltier is installed along the side wall of the sleeve, the first The constant temperature regulating module is used for regulating the temperature of the bioreactor placed in the accommodation space and keeping the bioreactor in a constant temperature state. Using Peltier to provide heat radiation to heat the bioreactor, the thermal inertia of Peltier is very small, and the cooling and heating time is fast; and the use of Peltier makes the bioreactor constant temperature system capable of continuous work, no pollution, No rotation effect, small vibration, low noise, long service life, easy installation and so on.

Description

technical field [0001] The invention relates to the technical field of cell culture, in particular to a bioreactor constant temperature system. Background technique [0002] In vitro cell therapy requires the use of bioreactors to carry cells for in vitro therapy. Cells must have a suitable and constant temperature for vigorous growth and corresponding functions in the bioreactor. In recent years, with the continuous development of stem cell therapy, immune cell therapy and gene editing and other basic theories, technical means and clinical medical research, cell therapy products have provided new treatment ideas and methods for some serious and refractory diseases; In vitro treatment first needs to culture the cells to keep the cells in a relatively stable state, and to maintain the vigorous growth and function of the cultured cells, a constant and suitable temperature must be maintained. Different types of cells have different requirements for culture temperature. The st...

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Problems solved by technology

[0004] Whether it is a water-proof constant temperature incubator or an electric constant temperature incubator, an insulation layer is generally installed. In addition, the heating device is relatively large, so the overall volume is relatively large, which also leads to an increase in the heating range and low heating efficiency.

Since the heating part heats the box and other parts at the same time, it is also necessary to install a heat dissipation device, which will bring a lot of noise, while the electric heating constant temperature incubator uses a blower to dissipate heat, which makes the noise even louder

Moreover, although the bioreactor can be placed in an incubator to maintain a constant temperature, when the treatment is performed, the bioreactor needs to exchange liquid, and the existing constant temperature incubator needs more heating power to keep the bioreactor at a constant temperature. Therefore, the existing constant temperature culture The box cannot meet the constant temperature requirements of the bioreactor

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