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Traditional Chinese medicine composition for treating blood deficiency and blood stasis type cervical spondylosis, preparation and application

A composition and technology for cervical spondylosis, applied in drug combinations, non-central analgesics, medical preparations containing active ingredients, etc., can solve problems such as poor treatment effect, prolonged treatment time, and unsatisfactory functional recovery effect

Active Publication Date: 2022-04-15
云南省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the commonly used drugs in clinical practice are not effective in the treatment of such diseases, resulting in prolonged treatment time for patients and unsatisfactory functional recovery.

Method used

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  • Traditional Chinese medicine composition for treating blood deficiency and blood stasis type cervical spondylosis, preparation and application
  • Traditional Chinese medicine composition for treating blood deficiency and blood stasis type cervical spondylosis, preparation and application
  • Traditional Chinese medicine composition for treating blood deficiency and blood stasis type cervical spondylosis, preparation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Prescription: Angelica 15g, Chuanxiong 15g; Rehmannia glutinosa 20g, Radix Paeoniae Rubra 15g; Guizhi 15g, Mori twig 20g, Pueraria 15g, Salvia miltiorrhiza 20g; Roasted licorice 6g. Put all the medicines in a pot, add water to submerge the medicines by 2~3cm, soak for 30 minutes, first boil on high heat, then change to low heat and fry for 30 minutes, and take about 150ml of juice. Add appropriate amount of water again, boil on high heat, fry on low heat for 10 minutes, take about 150ml of juice, and combine the soup to get a decoction.

Embodiment 2

[0035] Prescription: Angelica 30g, Chuanxiong 10g; Rehmannia glutinosa 15g, Radix Paeoniae Rubra 10g; Guizhi 10g, Morangzhi 10g, Pueraria 20g, Salvia miltiorrhiza 10g; Zhigancao 3g. Decoct each herbal flavor of the prescription with water at a weight ratio of 1:6, add water and decoct 1 to 3 times, 60 minutes each time, and combine the decoction liquid; concentrate the obtained decoction liquid at 65°C, -0.02~-0.06MPa vacuum degree to thicken Paste, the thick paste has a density of 1.35g / ml at 60°C; the thick paste is dried at 65°C under a vacuum of -0.02~-0.06MPa to form a dry paste, and the dry paste is crushed and passed through a 100-mesh sieve to obtain a mixed dry paste powder. Mix 10g of sucrose evenly, add an appropriate amount of 75% ethanol, wet granulate, and obtain granules after drying.

Embodiment 3

[0037] Prescription: Angelica 20g, Chuanxiong 15g; Rehmannia glutinosa 20g, Radix Paeoniae Rubra 15g; Guizhi 20g, Morangzhi 15g, Pueraria 30g, Salvia miltiorrhiza 15g; Zhigancao 9g. Weigh each medicinal herb in the formula according to the formula, add water to decoct 1 to 3 times according to the weight ratio of medicine to water 1:9, each time for 45 minutes, and combine the decoction; Concentrate into a thick paste under vacuum of -0.06MPa, and the density of the thick paste is 1.20g / ml at 50°C; dry the thick paste at 75°C under a vacuum of -0.02~-0.06MPa to form a dry paste, crush the dry paste and pass through 100 Mesh sieve to obtain the mixed dry cream powder, and water pills to obtain pills.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating blood deficiency and blood stasis type cervical spondylosis, a preparation and application. The traditional Chinese medicine composition is prepared from, by weight, 15-30 g of angelica sinensis and 10-15 g of ligusticum wallichii. 15-20 g of prepared rhizome of rehmannia and 10-15 g of radix paeoniae The traditional Chinese medicine is prepared from 10-20 g of cassia twigs, 10-20 g of ramulus mori, 15-30 g of And 3-9g of honey-fried licorice root. The traditional Chinese medicine for treating the blood deficiency and blood stasis type cervical spondylosis is intended to enrich blood, activate blood, remove blood stasis and dredge collaterals. Angelica sinensis and Ligusticum wallichii are used for promoting qi and activating blood to serve as monarch drugs to replenish blood without stagnation, regulate meridians and collaterals and qi and blood to relieve discomfort such as local pain and numbness, and cassia twig, ramulus mori, radix puerariae and the like are used for promoting blood circulation to relax tendons and dredge collaterals, so that the whole formula has the effects of promoting blood circulation to dissipate blood stasis, and all the drugs are used for tonifying without stagnation. The traditional Chinese medicine is precise and appropriate in compatibility, can quickly relieve numbness symptoms of upper limbs, shoulders and necks after being taken, relieves a muscle tension state, protects the stomach, promotes the secretion of saliva or body fluid and prevents a source of injury to qi and blood biochemistry. The total effective rate of the traditional Chinese medicine symptom treatment effect of the traditional Chinese medicine composition is 84.37%, the total effective rate of a control group is only 63.33%, and the treatment effect of the traditional Chinese medicine composition is remarkably superior to that of a western medicine control group in the aspect of treating blood deficiency and blood stasis type cervical spondylosis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions and preparations, and in particular relates to a traditional Chinese medicine composition, preparation and application for treating cervical spondylosis of blood deficiency and blood stasis type. Background technique [0002] Cervical spondylosis refers to the spinal cord, nerve, and blood vessel damage caused by degenerative disc disease and its secondary changes, as well as the corresponding symptoms and signs. At present, its etiology and pathogenesis are not completely clear in Western medicine, and it is generally believed to be the result of multiple factors acting together. Cervical spondylosis belongs to the category of arthralgia, wilt, and vertigo in traditional Chinese medicine. With the popularization of electronic products and changes in work and lifestyle, such as long-term office work, playing with mobile phones, and reading, the incidence of cervic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K36/815A61K36/8994A61P19/08A61P29/00
CPCY02A50/30
Inventor 陈涛邵水艳李川万青魏庆中郑远志彭中钰许帅刘盾
Owner 云南省中医医院
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