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Antiseptic Chinese medicine composition and its prepn process

A technology of antibacterial effect and composition, which is applied in the field of traditional Chinese medicine composition and preparation with antibacterial effect, and can solve the problems of troublesome use, no obvious curative effect of antibiotics, long course of disease, etc.

Inactive Publication Date: 2006-08-23
上海海天医药科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the non-standard use of antibiotics in clinical practice and the emergence of drug-resistant strains are simply worse for the majority of mycobacteria and chlamydia infections.
In this regard, at present, clinical treatment is carried out according to traditional Chinese medicine prescriptions, and good curative effect has been achieved. However, due to the confusion of clinical prescriptions and troublesome use, it brings a lot of inconvenience to patients.
[0003] Reproductive system and urinary system diseases caused by mycoplasma and chlamydia infection generally do not have acute onset and severe symptoms caused by bacterial infection in clinical practice. It often has mild symptoms, only discomfort, or even no obvious symptoms, and the course of disease is long. General antibiotics No obvious curative effect, and easy to relapse, can cause infertility and other diseases such as habitual abortion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] prescription

[0080] Scutellaria baicalensis 200g

[0081] Cork 200g

[0082] Hedyotis diffusa 200g

[0083] Honeysuckle 200g

[0084] Sophora flavescens 140g

[0085] Pulsatilla 200g

[0086] Makes 1000 capsules

[0087] method

[0088] Scutellaria baicalensis, Pulsatilla pulsatillae, and Hedyotis diffusa were extracted twice with 6 times the amount of 70% ethanol under reflux, each time for 2 hours, filtered, and the filtrate was combined for later use. times, each time for 2 hours, filtered to obtain the filtrate, combined the filtrate twice, reclaimed ethanol, concentrated into a thick extract, dried under reduced pressure at 60°C, pulverized, added appropriate amount of starch, and made 1000 capsules, that is, each Each capsule contains baicalin 8mg.

Embodiment 2

[0090] prescription

[0091] Scutellaria baicalensis 120g

[0092] Cork 240g

[0093] Hedyotis diffusa 160g

[0094] Honeysuckle 200g

[0095] Sophora flavescens 140g

[0096] Pulsatilla 140g

[0097] Makes 1000 pieces

[0098] method

[0099] Scutellaria baicalensis, Pulsatilla pulsatillae, and Hedyotis diffusa were extracted twice with 8 times the amount of 55% ethanol under reflux, each time for 2 hours, filtered, and the filtrate was combined for later use. times, each time for 2 hours, filtered to obtain the filtrate, combined the filtrate twice, recovered ethanol, concentrated into a thick extract, dried under reduced pressure, pulverized, added an appropriate amount of starch, granulated, dried, granulated, compressed into tablets, packaged Clothing, made into 1000 tablets, that is.

Embodiment 3

[0101] prescription

[0102] Scutellaria baicalensis 112g

[0103] Cork 72g

[0104] Hedyotis diffusa 60g

[0105] Honeysuckle 40g

[0106] Sophora flavescens 36g

[0107] Pulsatilla 80g

[0108] Makes 1000ml

[0109] method

[0110] Scutellaria baicalensis, Pulsatilla pulsatillae, and Hedyotis diffusa were extracted twice with 5 times the amount of 67% ethanol under reflux, each time for 2 hours, filtered, and the filtrate was combined for later use. Once, each time for 2 hours, filter to get the filtrate, combine the filtrate twice, recover ethanol, concentrate into a thick extract, add 200g of sucrose, 3g of sodium benzoate, stir well, add distilled water to make 1000ml, refrigerate for 24 hours , filtered, potted and sterilized.

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PUM

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Abstract

The antiseptic Chinese medicine composition is orally taken preparation comprising the active components extracted from skullcap root, phellodendron bark, flavescent sophora root, honeysuckle, pulsatillae root and oldenlandia and medicinal supplementary material. The Chinese medicine composition is developed based on Chinese medicine theory and prepared through modern extraction and analysis process, and has controllable effective components, stable quality and determined curative effect. The Chinese medicine composition is especially suitable for in preparing medicine for treating diseases of reproductive system and urinary system caused by mycoplasma and chlamydia infection.

Description

Technical field: [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition with antibacterial effect and a preparation method. Background technique: [0002] Mycoplasma and Chlamydia can cause multisystem disease in humans. In recent years, the incidence of NGU in nongonococcal urethritis has been increasing, especially the NGU caused by Chlamydia trachomatis CT and UU caused by Ureaplasma urealyticum has attracted much attention. According to foreign epidemiological surveys, the CT infection rate of young women accounts for 40%. Japanese Yasuda Nisuke and others reported in 1988 that the positive rate of cervical and endometrial CT detection in pelvic inflammatory disease patients was 20-40%. Since 1995, mycoplasma genitalium isolation and culture and PCR technology for rapid diagnosis research have been carried out in our country. The study found that the rate of UU in the cervix and vagina of ma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K36/74A61K36/71A61K36/539A61K36/489A61K36/35A61K31/7048A61K31/56A61K31/4375A61P31/00A61P31/04
Inventor 蒋毅黄育明彭旦明金凌
Owner 上海海天医药科技开发有限公司
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