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Extraction of styptic from cephalanoplos segetum

A drug and plant technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of the active ingredients of thistle are not refined, affect the curative effect and preparation quality, and the hemostatic effect is not obvious, and achieve obvious hemostatic effect, Fast-acting, powerful effects

Inactive Publication Date: 2007-05-30
郭俊京 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current extraction method of traditional Chinese medicine hemostatic medicine is very complicated. The active ingredients in thistle are not refined, and the purification degree is not high, which affects the curative effect and the quality of the preparation. The hemostatic time is relatively long, the hemostatic effect is not obvious, and the cost is relatively high.

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] Raw materials: thistle 1Kg;

[0012] The method for extracting hemostatic medicine from raw material thistle, the method steps are:

[0013] (1) Water decoction extraction: take 1Kg of thistle medicinal material, add 10 times the weight of the medicinal material, that is, 10Kg, decoct and extract for 2 hours, filter, add 10Kg of water to decoct and extract for 1 hour, combine the secondary extracts, and set aside;

[0014] (2) Concentration under reduced pressure: Concentrate the standby combined extracts under reduced pressure to a relative density of 1.06, let stand for 12 hours, and filter;

[0015] (3) Extract hemostatic drug: add concentrated hydrochloric acid to the above-mentioned filtrate to adjust to PH2-3, add ethyl acetate to extract 4 times, the total consumption of ethyl acetate is 10 times of the volume of the medicinal solution, and recover ethyl acetate under reduced pressure;

[0016] (4) Purification treatment: add water to dissolve it until the conce...

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Abstract

A process for preparing the styptic in the form of injection from cephalanoplos herb includes such steps as decocting, vacuum concentrating, macroreticular adsorbing and freeze drying.

Description

1. Technical field [0001] The invention relates to a method for extracting a hemostatic drug from a plant, in particular to a method for extracting a hemostatic drug from a thistle plant, and belongs to the technical field of drug extraction methods. 2. Background technology [0002] Bleeding is an important clinical symptom of many surgical and medical diseases, and most of them are clinically critical, acute and severe. Excessive bleeding can lead to shock and life-threatening. At the same time, bleeding is accompanied by pain and inflammation. If the bleeding cannot be stopped in time, it will accumulate in the body and cause other diseases. Therefore, hemostasis is an important means to deal with clinical hemorrhagic critical illness. In addition, from the perspective of military medicine, hemostatic drugs are one of the important contents of strategic drugs for combat preparation. Therefore, hemostatic drugs have a wide range of uses. [0003] At present, hemostatic d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61P7/04
Inventor 乔东虎张铁军郭俊京许浚
Owner 郭俊京
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