Application of Netilmicin sulfate in preparation of eye drops

Abstract

The present invention belongs to a preparation process of eye drops with obvious curative effect for curing keratitis due to pseudomonas and infective ophthalmopathies due to gram-negative bacteria, pseudomonas aeruginosa and other bacteria. Said eye drops preparation is of netilamicin sulfate which is used as main raw material and adding chemical inhibitor, antioxidation synergist, preservative, pH regulating agent, isoosmotic regulating agent, stabilizing agent and solvent as auxiliary material.

Description

technical field

[0001] The invention relates to a preparation process of medicine for treating ophthalmic diseases, in particular, an eye drop is mainly prepared by using netilmicin sulfate together with auxiliary materials. Background technique

[0002] At present, in clinical ophthalmic medicine, antibiotic chemicals have an absolute advantage. According to statistics, 80% to 90% of patients who visit ophthalmology clinics have outer eye infections. Topical administration is the main way of ophthalmic medicine, because local administration can not only make the concentration of the liquid medicine in the lesion part higher and maintain it for a long time, but also can greatly save medicine and reduce systemic side effects. Eye drops are the most commonly used topical drug formulation in ophthalmology. Among the eye drops for the treatment of eye inflammation, aminoglycosides, macrolides, quinolones, etc. are widely used clinically, and aminoglycosides have good permeabil...