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Chinese medicine drippling pill for treating coronary heart disease and its preparing method

A technique for coronary heart disease and drop pills, which is applied in the field of drop pills for the treatment of coronary heart disease and its preparation, can solve problems such as unretrieved patent information, and achieve the effects of improving bioavailability, fast onset of action, and favorable absorption

Inactive Publication Date: 2005-05-18
张平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Checked the patent information, but no relevant patent information was retrieved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] (1) The formula ratio of the raw material drug is

[0101] Salvia 38.4g, Sandalwood 4.3g, Fragrance 8.5g, Shannai 6.4g, Nutmeg 12.8g, Jujube 12.8g,

[0102] Seabuckthorn 12.8g.

[0103] (2) Extraction process

[0104] ① Put salvia, jujube and sea buckthorn into the extractor, add 125ml of 95% ethanol, and soak for 6 hours.

[0105] ②Place sandalwood, fenugreek, mangosteen and nutmeg in an extractor with a volatile oil collector, add 250 ml of water, extract for 5 hours, and collect 0.5 ml of volatile oil. The aqueous extract was filtered and concentrated.

[0106] ③ Extract the dregs of the volatile oil together with Salvia miltiorrhiza, jujube and sea buckthorn with 95% ethanol twice, 1 hour each time. Filter, combine the filtrates and concentrate.

[0107] ④ Add 250 ml of water to the medicinal residues after alcohol extraction, boil twice with water for 1.5 hours each time, filter, concentrate the filtrate, and combine with the concentrate of the water extract o...

Embodiment 2

[0113] (1) The formula ratio of the raw material drug is

[0114] Salvia 35g, Sandalwood 3g, Fragrance 7g, Shannai 5g, Nutmeg 10g, Jujube 10g, Seabuckthorn 10g.

[0115] (2) Extraction process

[0116] ① Put salvia, jujube and sea buckthorn into the extractor, add 120ml of 95% ethanol, and soak for 5 hours.

[0117] ②Place sandalwood, fenugreek, sansevieria and nutmeg in an extractor with a volatile oil collector, add 230 ml of water, extract 4 hours, and collect 0.42 ml of volatile oil. The aqueous extract was filtered and concentrated.

[0118] ③ Extract the dregs of the volatile oil together with Salvia miltiorrhiza, jujube and sea buckthorn with 95% ethanol twice, 1 hour each time. Filter, combine the filtrates and concentrate.

[0119] ④ Add 230ml of water to the medicinal residues after alcohol extraction, boil for 2 times for 1.5 hours each time, filter, concentrate the filtrate, and combine with the concentrate of the water extract of the oil extraction.

[0120] ⑤ ...

Embodiment 3

[0125] (1) The formula ratio of the raw material drug is

[0126] Salvia 42g, Sandalwood 5g, Fragrance 10g, Shannai 8g, Nutmeg 15g, Guangzao 15g, Seabuckthorn 15g.

[0127] (2) Extraction process

[0128] ① Put salvia, jujube and sea buckthorn into the extractor, add 135ml of 95% ethanol, and soak for 7 hours.

[0129] ②Place sandalwood, fenugreek, mango and nutmeg in an extractor with a volatile oil collector, add 275 ml of water, extract for 6 hours, and collect 0.58 ml of volatile oil. The aqueous extract was filtered and concentrated.

[0130] ③ Extract the dregs of the volatile oil together with Salvia miltiorrhiza, jujube and sea buckthorn with 95% ethanol twice, 1 hour each time. Filter, combine the filtrates and concentrate.

[0131] ④ Add 275 ml of water to the medicinal residues after alcohol extraction, boil twice with water for 1.5 hours each time, filter, concentrate the filtrate, and combine with the concentrate of the water extract of the oil extraction.

...

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Abstract

The Chinese medicine dripping pill for treating coronary heart disease consists of the extractive of Chinese medicine materials sandalwood, dalbergia wood, cyanide, nutmeg, red sage, axillary choerospondias fruit and sea-buckthorn in 17-24 weight portions; and medicinal supplementary material in 17-24 weight portions. In the extractive, volatile oil accounts for 2-2.5 %. The present invention features that the dripping pill connects neotanshionone IIA not less than 1.0 mg / g and total salvianoic acid not less than 14 mg / g. The pharmacological experiment shows that the dripping pill has excellent pharmacological effect.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and particularly relates to a dripping pill with the effect of treating coronary heart disease and a preparation method thereof. Background technique [0002] Coronary heart disease is short for coronary heart disease. It is a kind of coronary circulation disorder caused by fixed (atherosclerosis) or dynamic (vasospasm) stenosis or occlusion of the coronary arteries, resulting in an imbalance between myocardial oxygen supply and demand, resulting in myocardial ischemia, hypoxia or necrosis. A type of heart disease, also known as ischemic heart disease. The incidence of coronary heart disease increases with age, and the degree also increases with age. Some data show that, starting at the age of 40, the prevalence of coronary heart disease doubles for every 10-year-old increase. After the age of 50 for men and 60 for women, coronary arteriosclerosis develops rapidly...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P9/10
Inventor 张平
Owner 张平
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