Film-shaped, dissolvable preparations for active substance release and method for the production thereof

Abstract

The invention relates to a film-shaped preparation which is dissolvable in an aqueous media and is used to administer substances into the human or animal body. Said preparation contains at least one water-soluble polymer. The invention is characterised in that the preparation contains one or several components which produce a gas under the effect of humidity or in the presence of an aqueous medium or when high temperature modifications occur.

Description

technical field

[0001] The present invention relates to film-shaped preparations which are disintegrable in an aqueous medium and which are produced on the basis of water-soluble polymers and which can be used to administer substances to the human or animal body. The invention further relates to a process for the preparation of this formulation, as well as its use as a dosage form for pharmaceutical administration. Background technique

[0002] Flat dosage forms, especially oral dosage forms, which disintegrate in an aqueous environment and enable rapid release of active substances in the oral cavity or other orifices or cavities of the body are known. For example, such dosage forms may be presented in "wafer" form. Due to their relatively thin layer thicknesses and disintegratability or solubility, these film-shaped flat administration forms are especially suitable for the rapid release of drugs or other active substances in the oral cavity.

[0003] Flat wafer-like films...