Freeze drying preparation of amifostine, and preparation method
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 深圳市资福药业有限公司
- Publication Date
- 2005-11-16
Abstract
Description
technical field
[0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a freeze-dried amifostine preparation and a preparation method thereof. Background technique
[0002] Amifostine is an alkyl phosphorothioate compound (dihydrogen phosphorothioate S-2-(3-aminopropylamino) ethyl ester), it is a broad-spectrum selective cell protector, the main function is to protect Hematopoietic stem cells have obvious protective effects on red and white blood cells and platelets, and can reduce the toxic and side effects of radiotherapy and chemotherapy on the liver, kidney, heart, and nervous system. It is mainly suitable for the adjuvant treatment of tumor radiotherapy or cytotoxic chemotherapy. On the other hand, the combination of amifostine and radiotherapy or cytotoxic antineoplastic drugs can enhance the patient's tolerance to antitumor treatment, which is conducive to increasing the treatment dose and shortening the treatment period...