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Hepatitis treating medicine and its preparation method

A technology for drugs and hepatitis, applied in the field of drugs for the treatment of hepatitis, can solve the problems of obvious long-term effect, unclear active ingredients, obvious and precise western medicine, etc.

Inactive Publication Date: 2005-12-07
广西梧州三鹤药业股份有限公司
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  • Summary
  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

On the other hand, the long-term effect of traditional Chinese medicine in the treatment of hepatitis is obvious, but the short-term effect is far less obvious and exact than western medicine.
The main reason is that the active ingredients are not clear, and it is difficult to achieve symptomatic treatment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] 1. Preparation of medicinal liquid: Weigh the raw materials of medicinal liquid according to 200 mg of swertiamarin and 300 mg of peanut oil per soft capsule, and prepare the medicinal liquid.

[0039] The main ingredient has a purity of over 95%, and is crushed and passed through a 160-200 mesh sieve. Using a high-speed colloid mill (rotation speed greater than 3000 rpm), first put the main drug and auxiliary materials in a stainless steel bucket and stir until it becomes a paste, then inject it into the colloid mill and grind it for 3 hours until it is completely uniform and becomes a non-sedimentation suspension emulsion. .

[0040] 2. Glue preparation:

[0041] Select high-quality gelatin (freezing force ≥ 12°, pulling force ≥ 100°), high-quality glycerin (conforming to the requirements of the Chinese Pharmacopoeia) and purified distilled water. The ratio of the three is: 45%: 22.2%: 32.5%. In the melt glue tank, reduce the vacuum to 0.85MPa, heat at 70°C and stir...

Embodiment 2

[0045] According to 100 mg of swertiamarin, 500 mg of polyethylene glycol 400, and 30 mg of glycerin per soft capsule, the medicinal solution was prepared.

[0046] Weigh the raw materials of the liquid medicine, the purity of the main medicine is more than 95%, pass through a 160-200 mesh sieve after crushing, first put half of the above amount of polyethylene glycol and glycerin in a stainless steel bucket, and quickly put the weighed main medicine Put it into the barrel and stir with the auxiliary materials. After the main drug is dissolved, add the remaining auxiliary materials, stir well, and set aside. Then follow the other steps of Example 1 to make the finished product.

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Abstract

The invention provides a method for preparing medicament for treating hepatitis and its preparing process, wherein the medicament is a soft capsule preparation made from medicinal liquid and capsule casings, the constituents of each pill of the medicinal liquid include Swertiamarin 10-800 mg, and balancing medicinal auxiliary materials. The preparing process comprises the steps of (1) capsule casing preparation, (2) medicinal liquid preparation, (3) soft capsule preparation.

Description

technical field [0001] The invention relates to a medicine for treating hepatitis and a preparation process of the medicine. technical background [0002] The research and development of effective drugs for various types of hepatitis diseases is in the ascendant. However, because some pathological mechanisms of hepatitis are still unclear, Western medicine treatment is not only expensive, but also has large side effects, high rebound rate and recurrence rate, and the long-term curative effect is almost ineffective. Nothing can be done, so further research and evaluation are awaited. Therefore, although there are many drugs for the treatment of hepatitis at this stage, there is no specific drug for the treatment of hepatitis. Especially for hepatitis B, more than half of the acute hepatitis B patients are actually acute attacks of chronic hepatitis B disease, and the course of the disease is as long as One or twenty years, it is difficult to recover; some even gradually deve...

Claims

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Application Information

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Inventor 张丽玲
Owner 广西梧州三鹤药业股份有限公司
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