Use of traditional Chinese medicine garden burnet and its extract in preparing drug for raising red cell and blood hemoglobin

A technology of hemoglobin and extract, which is applied in the application field of medicine, can solve the problems of increasing white blood cells and platelets, increasing red blood cells and hemoglobin, etc., and achieves the effect of increasing red blood cells and hemoglobin, taking conveniently, and having remarkable curative effect

Inactive Publication Date: 2006-06-21
CHENGDU DIAO PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The increase of red blood cells and hemoglobin can improve the oxygen supply level and metabolic capacity in the body. White blood cells have the function of phagocytosis of bacteria. Therefore, the etiology, pathogenesis and pathology of the increase of white blood cells and platelets are different from those of red blood cells and hemoglobin. Burnet, Burnet extract, or various active ingredients of Burnet in raising red blood cells and hemoglobin for the treatment and / or prevention of anemia have been reported

Method used

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  • Use of traditional Chinese medicine garden burnet and its extract in preparing drug for raising red cell and blood hemoglobin
  • Use of traditional Chinese medicine garden burnet and its extract in preparing drug for raising red cell and blood hemoglobin

Examples

Experimental program
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Effect test

Embodiment 1

[0037] Embodiment 1 Preparation of the original drug of Burnet burnet

[0038] Take traditional Chinese medicine Sanguisorba officinalis L. or Sanguisorba officinalis L. longifolia Sanguisorba officinalis L.Var Longifolia (Bert) Yüet Li. After cleaning the dried root, grind it according to the conventional method, and sieve it to make a particle size of 60 ~ 80% elm fine powder, put the fine powder into capsules, sterilize, divide and pack. Each capsule weighs 0.12g, 2 times a day, 1 capsule each time.

Embodiment 2

[0039] Example 2 Preparation of Burnet Burnet Extract 1

[0040] Burnet 1000g, pulverized, added 8L of 70% ethanol solution, extracted under reflux for 1.5 hours, filtered, added 6L of 70% ethanol solution to the filter residue, extracted under reflux for 1 hour, filtered. Combine the two filtrates, concentrate to a certain concentration, and set aside for later use. The polyamide resin is packed into a column, the above extract is absorbed by a polyamide column, and then the column is eluted with 70% ethanol, the eluate is collected, the eluate is concentrated under reduced pressure, and the ethanol is recovered to obtain an extract. The obtained extract was heated and dissolved with water, and then passed through a polyamide column twice to obtain the extract, which was vacuum-dried to obtain 19 g of dry powder, which was the Burnet extract 1, wherein the total saponins content of Burnet accounted for 74% of the total weight.

Embodiment 3

[0041] Example 3 Preparation of Burnet Burnet Extract 2

[0042] Burnet 1000g, pulverized, added 8L of 80% ethanol solution, extracted under reflux for 1.5 hours, filtered, added 6L of 80% ethanol solution to the filter residue, extracted under reflux for 1 hour, filtered. Combine the two filtrates, concentrate to a certain concentration, and set aside for later use. The polyamide resin is packed into a column, the above-mentioned extract is absorbed by a polyamide column, and then the column is eluted with 75% ethanol, the eluate is collected, the eluate is concentrated under reduced pressure, and the ethanol is recovered to obtain an extract. The obtained extract was heated and dissolved with water, and then passed through a polyamide column once to obtain the extract, which was vacuum-dried to obtain 24 g of dry powder, which was the Burnet extract 2, wherein the total saponin content of Burnet accounted for 55% of the total weight.

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Abstract

The present invention relates to the new use of Chinese medicine garden burnet and its extract in preparing medicine, and is especially the use of Chinese medicine garden burnet and its extract in preparing medicine for increasing erythrocyte and hemoglobin. Garden burnet and its extract may be used in preventing and treating various kinds of anemia, especially anemia caused by anematopoiesis or hematopoietic function failure of marrow. The present invention has the advantages of small dosage, obvious curative effect, low cost and convenient use.

Description

technical field [0001] The invention relates to a new application of the traditional Chinese medicine Burnet, in particular to the application in the preparation of medicines for increasing red blood cells and hemoglobin, and belongs to the field of traditional Chinese medicines. Background technique [0002] Under normal conditions, the production and decay of red blood cells maintain a dynamic balance, which keeps the values ​​of red blood cells, hemoglobin, and hematocrit per unit volume stable. Anemia results from reduced red blood cell production, excessive destruction, or both. Anemia caused by decreased red blood cell production mainly includes: 1) Insufficient hematopoietic raw materials or utilization disorders, such as anemia caused by abnormal iron metabolism, folic acid or B 12 Anemia caused by abnormal metabolism, etc.; 2) low or failure of bone marrow hematopoietic function, such as aplastic anemia; 3) secondary anemia caused by various diseases; anemia caused...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/739A61K31/704A61K125/00A61P7/00A61P7/06
CPCA61K31/704A61K36/739A61P7/00A61P7/06
Inventor 高小平邹文俊吴建明邓义龙刘忠荣李伯刚
Owner CHENGDU DIAO PHARMA GROUP
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