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Composition with effect of promoting leukopoiesis and preparation method thereof

A composition and white blood cell technology, applied in the direction of medical preparations containing active ingredients, drug combinations, pharmaceutical formulas, etc., can solve problems such as body aches, poor curative effect, and fever

Inactive Publication Date: 2018-11-16
XIAN GIANT BIOGENE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many types of leukocyte-increasing drugs, such as leucogen, batyl alcohol, etc., but the curative effect is not good
Although recombinant human granulocyte colony-stimulating factor has a good effect, it is expensive, and often has adverse reactions such as fever and body aches, which limit its clinical application.

Method used

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  • Composition with effect of promoting leukopoiesis and preparation method thereof
  • Composition with effect of promoting leukopoiesis and preparation method thereof
  • Composition with effect of promoting leukopoiesis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Example 1 The raw materials were weighed according to the following formula: 30 parts of astragalus, 20 parts of papaya, 15 parts of poria cocos, 15 parts of wolfberry, 7 parts of angelica, 10 parts of ginseng, 5 parts of donkey-hide gelatin, and 12 parts of royal jelly. Astragalus, papaya, poria cocos, wolfberry, and angelica were added in proportion to 10 times of water, extracted twice under reduced pressure at 100°C, 2 hours each time, combined the extracts, concentrated to a paste, added ginseng powder, donkey-hide gelatin powder, appropriate amount of royal jelly, and mixed well Crush and granulate. Pour into capsules, 0.4g per capsule.

Embodiment 2

[0064] Example 2 The raw materials were weighed according to the following formula: 35 parts of astragalus, 15 parts of papaya, 15 parts of poria cocos, 15 parts of wolfberry, 7 parts of angelica, 8 parts of ginseng, 5 parts of donkey-hide gelatin, and 15 parts of royal jelly. Astragalus, papaya, poria cocos, wolfberry, and angelica were added in proportion to 10 times of water, extracted twice under reduced pressure at 100°C, 2 hours each time, combined the extracts, concentrated to a paste, added ginseng powder, donkey-hide gelatin powder, appropriate amount of royal jelly, and mixed well Crush and granulate. Pour into capsules, 0.4g per capsule.

Embodiment 3

[0065] Example 3 The raw materials were weighed according to the following formula: 35 parts of astragalus, 15 parts of papaya, 15 parts of poria cocos, 20 parts of wolfberry, 10 parts of angelica, 10 parts of ginseng, 3 parts of donkey-hide gelatin, and 15 parts of royal jelly. Astragalus, papaya, poria cocos, wolfberry, and angelica were added in proportion to 10 times of water, extracted twice at 100°C under reduced pressure, 2 hours each time, combined the extracts, concentrated to a paste, added ginseng powder, donkey-hide gelatin powder, appropriate amount of royal jelly and a certain amount Excipients, mixed and crushed, wet granulated and pressed into tablets, 0.4g per tablet.

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PUM

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Abstract

The invention relates to a composition with the effect of promoting leukopoiesis and a preparation method thereof. The preparation method comprises the following steps: mixing crude drugs which are radix astragali, fructus chaenomelis, poria cocos and radix angelicae sinensis to obtain a mixture, extracting twice with water 10-20 times the amount of mixture, every time being 2 hours, combining andextracting the extracting liquor into paste, vacuum-drying, crushing and screening; adding crushed and screened mixture of colla corii asini and radix ginseng, and adding royal jelly to pelletize. The traditional Chinese medicine composition disclosed by the invention has obvious effects of increasing leukocyte and improving immunity, further can assist and inhibit cancer cell increase, and has remarkably reduced toxic and side effects in comparison with that of a leukocyte increasing drug on the market.

Description

technical field [0001] The invention belongs to the field of biochemical industry, and in particular relates to a composition with the effect of promoting leukocyte production and a preparation method thereof. Background technique [0002] In recent years, the incidence of malignant tumors has increased significantly. Chemoradiotherapy is a commonly used treatment plan for patients with malignant tumors after surgery. However, chemoradiotherapy is often accompanied by symptoms such as dizziness, vomiting, fatigue, limp limbs, loss of appetite, and listlessness. Among them, bone marrow cells are inhibited. Growth is the most serious side effect of radiotherapy and chemotherapy. Generally, 50% to 70% of patients will experience leukopenia, and even red blood cells, hemoglobin, and platelets will also decrease, resulting in serious infection and life-threatening patients. Therefore, part of the reason for the high mortality rate of malignant tumors is the poor effect of postope...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P37/04A61K35/36A61K35/644
CPCA61K35/36A61K35/644A61K36/076A61K36/232A61K36/258A61K36/481A61K36/732A61K36/815A61K2236/331A61K2236/39A61K2236/51A61P37/04A61K2300/00
Inventor 范代娣黄蓉马晓轩严建亚段志广
Owner XIAN GIANT BIOGENE TECH CO LTD
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