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Anti-inflammatory analgesic adhesive patch

An anti-inflammatory analgesic and patch technology, which is applied in the direction of anti-inflammatory agents, non-central analgesics, medical raw materials derived from angiosperm subphylum, etc., can solve problems such as insufficient effects, so as to relieve skin irritation and relieve pain. Uncomfortable stimulation, excellent anti-inflammatory and analgesic effects

Inactive Publication Date: 2006-07-19
TEIKOKU SEIYAKU KK TEIKOKU SEIYAKU CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to reduce such irritation and pain, various herbal medicine ingredients have been combined to alleviate the irritation, but until now, sufficient effects have not been obtained, and improved products need to be researched

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3

[0043] Embodiment 1~3: Water-based poultice

[0044] The water-based poultice of the composition shown in the following Table 1 is prepared according to the usual method, and it is coated on a non-woven fabric with a uniform thickness, and further covered with polyethylene terephthalate on its surface to obtain the water-based poultices of Examples 1-3. Poultice.

[0045] Element

Embodiment 4

[0049] Embodiment 4: Ointment

[0050] According to the following recipe, melt and mix styrene-isoprene-styrene block copolymer, alicyclic saturated hydrocarbon resin, synthetic rubber and dibutyl hydroxytoluene, then add vanillyl nonanoic acid and methyl salicylate , dl-camphor, and benzocaine are uniformly mixed, and spread on a carrier film to obtain an ointment.

[0051] prescription:

[0052] Nonanoic acid vanillamide 0.01% by weight

[0053] Methyl salicylate 5.0% by weight

[0054] dl-Camphor 2.0% by weight

[0055] Benzocaine 5.0% by weight

[0056] Styrene-isoprene-styrene block copolymer 22.0% by weight

[0057] Alicyclic saturated hydrocarbon resin 46.99% by weight

[0058] Synthetic rubber 18.0% by weight

[0059] Dibutylhydroxytoluene 1.0% by weight

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PUM

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Abstract

An anti-inflammatory analgesic adhesive patch which has an excellent anti-inflammatory analgesic effect and is reduced in unpleasant irritant feeling during wear. It is characterized by containing, as active ingredients, benzocaine and an ingredient having a counter-irritation effect, wherein the ingredient having a counter-irritation effect comprises one or more members selected from the group consisting of 1-menthol, dl-menthol, dl-camphor, d-camphor, methyl salicylate, glycol salicylate, peppermint oil, eucalyptus oil, capsaicin, capsicum extract, and nonylic acid vanillamide and the benzocaine is contained in an amount of 0.5 to 20 wt.%.

Description

technical field [0001] The present invention relates to a patch containing benzocaine and a component having a counter-irritation effect as active ingredients, and is used for muscle pain, joint pain, lumbago, shoulder stiffness, fracture pain, and the like. More specifically, it relates to an anti-inflammatory and analgesic patch that reduces discomfort during application and exhibits excellent effects. Background technique [0002] For a long time, the medicine containing l-menthol, dl-camphor, methyl salicylate and other active ingredients has been coated with an adhesive layer on non-woven fabrics, woven fabrics, polyvinyl chloride films and other carriers, and then polypropylene films, Various anti-inflammatory and analgesic patches are commercially available in which a polyethylene terephthalate film, a release film of paper or the like is coated on the surface of a drug-containing adhesive layer. [0003] In addition, as a warm-sensing patch widely used in chronic di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/245A61K31/125A61K9/70A61K31/60A61K45/00A61K36/81A61P29/00A61K31/618A61K36/18A61K36/53A61K36/534A61K36/61A61K45/06
CPCA61K36/534A61K45/06A61K31/60A61K36/61A61K36/81A61K31/125A61K31/245A61K9/7053A61K9/7076A61P25/04A61P29/00A61K2300/00A61K9/70
Inventor 小西达也阿部康子町田裕治
Owner TEIKOKU SEIYAKU KK TEIKOKU SEIYAKU CO LTD
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