129results about How to "Good anti-inflammatory and analgesic effect" patented technology

The invention relates to a method for cultivating saussurea involucrate cell, wherein it comprises that using MS basic culture medium wit some NNA (fruitone), 6-BA (6-aminopurine) as the culture medium of callus; inducing the seed of saussurea involucrate into plant; using said plant as expalnt to be differented at special condition, to induce callus; subculturing the callus periodically, to increase the callus; using part of callus to function the seed and collecting the left to be dried as the saussurea involucrate culture; collecting said culture to be dried as the cell culture. The invention can improve the content of effective components.

The invention relates to the technical field of medicine application, and particularly relates to a liquid medicine for preventing and treating allergic rhinitis and wet tissue or tissue prepared by applying the liquid medicine. The liquid medicine is prepared from the following raw materials in parts by weight: 10-90 parts of magnolia flower, 5-40 parts of centipeda minima and 5-40 parts of cocklebur fruit. The wet tissue and tissue for preventing and treating allergic rhinitis by applying the liquid medicine are prepared from natural skin-friendly non-irritative materials, comprise a plurality of traditional Chinese medicinal effective components with the effects of resisting rhinitis and restoring nasal cavity, and are used for preventing and relieving discomfort of the nose of a patient with allergic rhinitis in daily life and non-invasively cleaning snot and other excretions when rhinitis attacks. Traditional Chinese medicine is developed to the tissue mode which is concise and convenient, the tissue has good application value and market prospect, is advantageous to popularize modern application of traditional Chinese medicines, and is beneficial to pain relieving of patients with allergic rhinitis.

The invention relates to a Chinese traditional medicine active extract, a preparation method thereof and an application thereof, particularly relates to an effective part extracted from a Chinese traditional medicine Qinglongyi, its preparation method and its application. The Qinglongyi active extract is prepared by the following steps of ethanol diacolation, reflux, ultrasonic extraction, CO2 supercritical extraction, ethanol precipitation, elution, interception, reflux, concentration, dryness and the like. According to the invention, the anticancer activity of the Qinglongyi effective part is taken as an index for screening the effective part of Qinglongyi, efficacy tests are carried out by using the extract with different contents, the result proves that an effective component in the Qinglongyi active extract for treating cancer is total naphthoquinone; the efficacy test result proves that an effective component for anti-inflammatory analgesic effect is total flavonoid, total tannin and polar micromolecules; a substrate for improving immune function is polysaccharide.

The invention discloses a wikstroemia indica (L.) C.A.Mey extract as well as a preparation method and application thereof. The wikstroemia indica (L.) C.A.Mey extract has the effective compositions of: naringenin, 5, 6, 7- trihydroxy-4'-methoxyflavanone, p-hydroxybenzoic acid, benzoic acid, quercetin glycoside,genkwano1 B, daphnoretin, Lirioresinol, Sikokianin and the like. The invention simultaneously provides application of the wikstroemia indica (L.) C.A.Mey extract, in particular the favorable application in preparing anti-cancer or anti-inflammation analgesia drug. A cytotoxicity experiment shows that the wikstroemia indica (L.) C.A.Mey extract disclosed by the invention has cytotoxicity functions on breast cancer of human, breast cancer drugresistant cell strain, mouse breast adenocarcinoma, which are in linear relation.

The invention relates to a giant salamander Chinese herbal medicine compound preparation for treating hepatitis B. The preparation is prepared from giant salamander tissue and the following Chinese herbal medicines in parts by weight: 35-45 parts of medlar, 25-35 parts of lucid ganoderma, 10-14 parts of coptis chinensis, 13-16 parts of radix sophorae flavescentis, 10-14 parts of selfheal, 13-16 parts of radix scutellariae, 16-20 parts of isatis roots, 16-20 parts of honeysuckles, 8-12 parts of dendrobium officinale and 6-10 parts of ginseng, wherein the giant salamander tissue comprises 500-3000 parts of giant salamander liver and 5-9 giant salamander gallbladders. The preparation method of the preparation comprises the following steps: grinding and mixing the giant salamander tissue, steaming for 8-12 minutes at 85-95 DEG C and freezing to obtain a giant salamander tissue mixture; smashing medlar, lucid ganoderma, coptis chinensis, radix sophorae flavescentis, selfheal, radix scutellariae, isatis roots, honeysuckles, dendrobium officinale, ginseng and spiral seaweed to obtain a Chinese herbal medicine mixture; and mixing the giant salamander tissue mixture with the Chinese herbal medicine mixture. The preparation provided by the invention not only has a good antiviral performance, but also can effectively enhance the antigen binding affinity and the immunity to protect liver activity and promote recovery of damaged liver cells and the like. The preparation for treating hepatitis B is remarkable in curative effect.

The invention relates to a composition for improving bone and joint health. The composition is prepared from the following components in parts by weight: 1-6 parts of non-denatured II-type collagen, 10-50 parts of cartilage collagen, 10-50 parts of mussel powder, 2-10 parts of olive fruit powder, 2-10 parts of rhizoma curcumae longae, 30-50 parts of sugar, 10-40 parts of starch, 5-20 parts of microcrystalline cellulose and 1-5 parts of magnesium stearate. The raw materials of the non-denatured II-type collagen, the cartilage collagen, the mussel powder, the olive fruit powder, the rhizoma curcumae longae and the like are adopted, thus cartilage core nutrition can be supplemented, cartilage lubrication liquid is promoted to be generated, meanwhile, inflammatory factors caused by the cartilage loss can be inhibited, thus the effects such as relieving joint pain are achieved, and the effect on improving osteoarthritis is significant.

The present invention relates to one kind of compound triptolide alcohol preparation for being injected into articular cavity to treat osteoarthritis. It includes triptolide alcohol solution of 1*10<-4> to 5*10<-2> mg / ml concentration and gel liquid mixed in the volume ratio of 1 to 1-9. It has medicine slow releasing effect, and this can prolong the action period of medicine, reduce consumption of triptolide alcohol and lower the toxic side effect of the medicine. It can inhibit the further development of osteoarthritis in early and middle phase, improve the environment inside the joint and promote the regeneration and repair of articular cartilage to reach the aim of cure osteoarthritis.

The present invention discloses deuterated benzopyran compounds having structure features as shown in Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or prodrug molecules thereof. With excellent anti-inflammatory and analgesic effects and the capability to inhibit growth of tumor cells, such compounds are novel COX-2 selective inhibitors. The compounds and pharmaceutically acceptable salts thereof disclosed by the present application can be applied in preparing anti-inflammatory and analgesic drugs and drugs for treating or preventing tumors.

The invention discloses a Chinese medicine combination used for treating pelvic inflammation and an extracting method thereof; the combination consists of red tasselflower, oldenlandia diffusa, rose mallow root, baibeiyegen radix malloti apeltae, pennycress, spatholobus stem and downy rosemyrtle root. The medicine combination can be divided into two groups, one group includes red tasselflower, oldenlandia diffusa and spatholobus stem which are extracted by 30-80 percent of ethanol (volume ratio) and the other group includes baibeiyegen radix malloti apeltae, pennycress, rose mallow root and downy rosemyrtle root which are extracted by water. The method increases the content of active ingredients in the extract and improves the effect of the extract used for treating pelvic inflammation.

The invention discloses bacteriostatic mouthwash for mouth care. The bacteriostatic mouthwash is prepared from raw materials in parts by weight as follows: 20-30 parts of clove, 15-25 parts of liquorice, 25-40 parts of honeysuckle vines, 10-18 parts of mint, 5-12 parts of tea polyphenols, 2-5 parts of malic acid, 0.25-0.75 parts of sodium monofluorophosphate, 3-8 parts of sodium chloride, 1-3 parts of a surfactant, 0.5-1.5 parts of an organic silicone antifoaming agent, 1-3 parts of a flavoring agent, 8-15 parts of ethanol and 50-70 parts of water. The bacteriostatic mouthwash for mouth care has a good cleaning effect, a bacteriostatic effect and anti-inflammation and pain relieving effects, is used for daily mouth care, can effectively remove oral residues and oral odors and effectively enhance oral immunity, plays an effective role in relieving oral diseases such as bad breath, oral ulcer and the like and tooth diseases such as periodontitis, tooth injuries and the like, tastes sour and sweet, has faint pleasant fragrance and has broad application prospect.

The invention discloses anti-inflammatory or analgesic activity of novel C20 ditepenoid alkaloid compounds (I) and (II) which can be dose-dependently achieved under safe dosage. Animal experiment results prove that the compounds 3 have a remarkable effect of inhibiting ear swelling of mice and an analgesic effect, and is expected to become a medicine for treating diseases related to inflammation and / or pains.

The invention discloses a novel compound and a preparation method thereof, as well as a pharmaceutical composition with the compound as an active ingredient and the effects and the uses thereof. The inventive compound and the pharmaceutical composition with the compound as the active ingredient can be used for treating tumors, relieving tumor pain, and enhancing immunity.

The invention provides a preparation process of an effective part of flower of abelmoschus manihot-a total flavone extractive and a new use thereof, in particular relating to the use in preparing medicines for treating acute and chronic gastritis, peptic ulcer, burns and scalds, traumatic infections and tumors and carbuncles.

The invention discloses enteromorpha feed for dairy cattle and a preparation method thereof. The feed is prepared from the following raw materials: enteromorpha powder, soybean cakes, mangosteen peels, fresh arrowhead solid bulbs, fresh purslane, fresh aloes, eucalyptus globulus, hemistepta lyrata, Guangdong erythrina indica lam, fresh ginseng fruits, humifuse euphorbia herb, houttuynia cordata, corydalis bungeana turcz, indigo naturalis and prepared liquorice roots. According to the feed disclosed by the invention, wastes are changed into valuable things and the enteromorpha is used as a main raw material, so that the nutritional components are sufficiently utilized; the feed is used as concentrated feed of the dairy cattle and can sufficiently provide microelements and vitamins needed in the feed, and the microelements and the vitamins do not need to be additionally added; meanwhile, the milk yield can be improved, the morbidity of mammitis of the dairy cattle is reduced, the utilization of substances including antibiotics, hormones and the like is effectively avoided, so that the pollution to milk products is avoided, and the eating safety of the milk products is ensured.

The invention discloses a watermelon vine extract with inflammation-diminishing and pain-relieving effects, which is a petroleum ether part prepared by alcohol precipitation and water extraction on watermelon vine. Researches discover that the extract has an excellent activity of diminishing inflammation and relieving pain, and can be applied to clinical treatment of rheumatic arthritis, rheumatoid arthritis, scapulohumeral periarthritis, bone and joint pain, cervical and lumbar pain, soft tissue pain, sprain pain and other diseases. According to the watermelon vine extract, the rich resource of the watermelon vine which is the crop waste can be sufficiently utilized, a powerful theoretical basis is provided to further research and development of medical values and clinical significance in the future, and a novel modern traditional Chinese medicinal preparation with excellent inflammation-diminishing and pain-relieving effects is expected to be provided to clinical application.

The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating scapulohumeral periarthritis, which is prepared from Chinese angelica, fossil fragments, radix aconite, frankincense, Buthus martensi Kirsch, common myrrh, liquorice, Stauntonia elliptica, cassia stems, Heracleum hemsleyanum, Salvia miltiorrhiza, lopseed, radix codonopsitis, eucommia barks, radix aconiti feri, bidentate achyranthes, litharge, Sichuan notopterygium roots, radix sileris and sesame oil according to weight. The traditional Chinese medicine composition has the advantages of low cost, good treatment effect, quick curing and promotion and application value.

Disclosed is a Chinese medicinal preparation for treating periarthritis humeroscapularis, wherein the constituents include Chinese angelica root 30g, Schizonepeta tenuifolia 15g, black-tail snake 12g, pilose asiabell root 30g, buthus martensi kirsch 12g, eucommia bark 15g, speranskia herb 15g, licorice root 12g, Ligusticum wallichii 15g, Sichuan aconite root 12g, large-leaf gentian root 15g, ledebouriella root 15g, batryticated silkworm 15g, pubescent angelica root 15g, radix rubiae 15g, polygala root 15g, safflower 15g, Kusnezoff monkshood root 15g, cassia twig 15g, astragalus root 30g, notopterygium root 15g and dragon's bone 15g.

The invention discloses a composition for treating lumbago and a preparation method of the composition, and aims at providing a traditional Chinese medicine composition which is capable of activating blood, dredging collaterals, relieving swelling and pain and effectively treating lumbago, and is small in side effect. According to the technical main points, the composition is prepared from the following components in parts by weight: 50-100 parts of rose mallow root whole plants, 50-100 parts of mirabilis jalapa whole plants, 30-100 parts of impatiens balsamina whole plants, 100-150 parts of paederia scandens whole plants, 30-100 parts of sansevieria trifasciata leaf whole plants and 10-30 parts of ginger. The composition belongs to the technical field of the traditional Chinese medicine.

The invention discloses pronephrium triphyllum-rheum officinale gel and a preparation method thereof, the pronephrium triphyllum-rheum officinale gel comprises the following components: pronephrium triphyllum, rheum officinale, herba commelinae, capparis acutifolia, radix helicteris, borneol, glycerin, carbomer-940, sodium hydroxide, ethyl nipagin ester, anhydrous alcohol, and distilled water. The preparation method comprises the following steps of: A. component weighing; B. medicinal material extraction; C. blank matrix preparation; D. gel preparation.

The invention provides an external composition for relieving pain of hyperplasia of mammary glands. The formula of the external composition sequentially comprises the following medical components in percentage by weight: 0.2-2 percent of salviae miltiorrhizae extract, 0.2-6.6 percent of clove oil, 0.6-5.8 percent of zedoary turmeric oil, 0.4-1.8 percent of angelica oil, 2.2-21 percent of sweet almond oil and 1.1-3.2 percent of chamomile oil. The external composition provided by the invention is simple in medicinal components and convenient to use and has a good effect of relieving breast pain. The external composition can simultaneously relieve the restless mood of patients caused by the pain, so that the psychological burdens of the patients suffering from the breast pain can be alleviated.

The invention belongs to the technical field of ointment preparations, and in particular relates to a method for preparing an external paste for treating arthralgia. The method comprises the following steps: cutting rubber into strips, rolling into thin rubber sheets, swelling and emulsifying in a gasoline solvent, putting raw materials into the gasoline solvent with the thin rubber sheets, uniformly stirring, filtering so as to obtain rubber slurry, coating a back lining with the slurry so as to obtain an ointment paste, and performing scrolling, lining covering and packaging. The external paste for treating arthralgia, which is prepared by using the method, has the advantages that the paste is good in function of inflammation diminishing and pain relieving, low in volatilization and long in medicinal effect lasting, the rubber is good in swelling emulsion effect, low in gasoline residue and not liable in solvent exosmosis, the paste lining is good in packaging effect and not easy to moisten, materials are uniformly dissolved and dispersed, and the ointment is uniform in quality, good in antibacterial effect and inflammation diminishing effect and long in preservation period.

The invention discloses injection for treating the mastitis of female minks and a preparation method of the injection. 1000ml of the injection comprises 20g of mannitol, 60g of sodium chloride and 80g of traditional Chinese medicine extract. The traditional Chinese medicine extract comprises, by weight, 5-9 parts of Oldenlandia diffusa, 4-6 parts of perfoliote knotweed herb, 7-11 parts of mangosteen peel, 15-17 parts of fresh fig, 8-15 parts of fresh herba portulacae, 6-8 parts of radix zanthoxyli leaf, 4-6 parts of radix sophorae flavescentis, 4-6 parts of cowherb seed, 2-5 parts of euphorbia humifusa, 5-8 parts of Lycium ruthenicum, 1-3 parts of Pilea japonica, 1-2 parts of Ainsliaea fragrans Champ., 2-3 parts of salviae miltiorrhizae and 3-5 parts of Turpinia formosana. The injection prepared by natural food materials and Chinese herbal medicine materials is safe, free of side effect, capable of replacing antibiotics, capable of effectively treating the mastitis of the female minks, capable of replenishing the nutrition needed by the female minks and capable of guaranteeing the healthy growth the female minks and young minks.

The invention relates to a new application of a pharmaceutical composition in preparing fracture treatment medicines. The prescription comprises: 66 parts of astragalus root, 27 parts of red paeonia, 27 parts of salvia miltiorrhiza, 27 parts of angelica, 27 parts of ligusticus wallichii franchet, 27 parts of peach kernel, 13 parts of safflower, 13 parts of olibanum, 13 parts of myrrh, 20 parts of caulis spatholobi, 27 parts of achyranthes, 20 parts of cassia twig, 27 parts of mulberry twig, 27 parts of earthworm, 13 parts of scorpion and 27 parts of leech; the medicament forms include: pills, granules, hard capsules, soft capsules, tablets, dripping pills or oral liquid. The invention aims at providing a new therapeutic application of the pharmaceutical composition, expanding the clinical application range of the invention and avoiding the waste of good medicine resources.

The invention relates to a plant bactericide capable of preventing and treating pest and disease damage. The bactericide is prepared from the following active ingredients in mass fraction: 80 to 100 parts of calamine, 80 to 100 parts of cyrtomium rhizome, 80 to 100 parts of chinaberry bark and root bark, 50 to 70 parts of fructus cnidii, 50 to 70 parts of hydrargyri oxydum rubrum, 50 to 70 parts of radix tripterygii wilfordii, 50 to 70 parts of lightyellow sophora root, 40 to 60 parts of fatty alcohol polyoxyethylene ether, 40 to 60 parts of glycerin and 140 to 160 parts of distilled water. The plant bactericide disclosed by the invention has the advantages of high efficiency, environmental friendliness and suitable for being applied and popularized in a large scale in agricultural production.

The invention relates to an inflammation-diminishing analgesia liquid of dental diseases, which is prepared by soaking Chinese herbal medicines with white spirit, wherein the Chinese herbal medicines comprise the following components by weight percent: 15 percent of asarum, 15 percent of radix sileris, 15 percent of cloves, 15 percent of angelica, 20 percent of menthol and 20 percent of Chinese prickly ash. After being cleaned and dried, in accordance with the weight percent of 1:1, the Chinese herbal medicines are soaked with the white spirit for 10-20 days and then can be used, or are respectively grinded into powder and subpackaged with cloth bags and tied, and then soaked with the white spirit for 3 days in accordance with the weight percent of 1:1.5, and later can be used, and then the alcohol content of the white spirit is over 55 degrees; and before use, the solids are filtered, the impurities are removed, and the liquid is placed into a bottle for reserve. The inflammation-diminishing analgesia liquid of dental diseases has wide therapeutic effect on the toothache diseases which are caused by various causes, can be used with a dropping compress method, is very simple and convenient, has obvious therapeutic effect, and belongs to the improvement on the basis of a family biography secret prescription. After long years of therapeutic practice to a plurality of patients, the inflammation-diminishing analgesia liquid of dental diseases has the advantages of reliable effect, short treatment period, pure Chinese herbal medicine preparation, and non-toxic side effect.

The present invention relates to a burn ointment for treating burns and scalds and the preparation method thereof, which pertains to the Chinese traditional patent medicines and the preparation technical field, the present invention aims at solving the technical problem of: providing the burn ointment which can promote the wound healing as soon as possible, prevent the wound infection, prevent and reduce the scar formation and the preparation method thereof. The parts by weight of the raw materials of the burn ointment are: champion bauhinia: 15 to 90; anoectochilus formosanus: 3 to 18; stearate: 1 to 10; glycerol stearate: 0.2 to 2; sesame oil: 2 to 20; liquid paraffin: 1 to 10; beeswax: 1 to 10; glycerol: 3 to 30; triethanolamine: 0.15 to 1.5; ethyl paraben: 0.01 to 0.2; distilled water: 5 to 50; borneol: 0.02 to 0.5. The preparation method is that the base materials are added in proportion after the pretreatments of powder making and solvent extraction according to the different characteristics of raw materials, so as to prepare the ointment. The external application of the present invention has the treatment effects of rapid pain stopping, fast wound healing, strong anti-infective ability and no scars, furthermore the use is convenient, the operation is simple and the cost is low.

The invention relates to plaster. The plaster is prepared from, by mass, 15-30 g of safflower carthamus, 15-30 g of rhizoma curcumae, 15-40 g of ligusticum wallichii, 15-40 g of prepared kusnezoff monkshood roots, 15-50 g of processed radix aconiti, 15-50 g of radix notoginseng, 15-50 g of ground beetles, 15-30 g of mastic, 15-50 g of menthol, 15-30 g of bark of eucommia, 15-30 g of radix angelicae pubescentis, 15-30 g of notopterygium roots, 15-40 g of dipsacus asper wall., 15-50 g of roots of largeleaf gentian, 15-40 g of musk, 15-40 g of cornu cervi pantotrichum, 15-40 g of hippocampus japonicus, 15-30 g of centipede and 15-50 g of turtle shells. A specific preparation method of the plaster includes the steps that the materials are mixed and smashed into powder materials, and the powder materials are prepared into the plaster through a conventional method. The plaster can effectively treat bone diseases, cervical spondylosis, lumbar disc herniation, periarthritis of shoulders, sciatica, synovitis, bone hyperplasia, rheumatoid arthritis, ankylosing spondylitis, strain of lumbar muscles, meniscus injury, traumatic injuries, cold in uterus, dysmenorrheal and other diseases, and the use effect is good.

The invention relates to the field of traditional Chinese medicine extraction, and particularly discloses an aquilaria sinensis leaf extract as well as a preparation method and an application thereof. The extract comprises the following six components: 2-O-a-rhamnoside-4,6,4'-trihydroxybenzo phenone, 3-C-heteroside-2,4,6,4'-tetrahydroxybenzophenone, mangiferin, 3.5-C-glucoside-2,4,6,4'-trihydroxybenzo phenone, 5,4-dimethoxy-7-hydroxy flavone and apione-7,4'-dimethyl ether. The aquilaria sinensis leaf extract has good anti-inflammatory and analgesic effects and can be used for preparing anti-inflammatory and analgesic drugs; and the effective constituents in the extract are clear so that benefit is brought to the medication safety.