Watermelon vine extract with inflammation-diminishing and pain-relieving effects, as well as preparation method and application thereof

An anti-inflammatory, analgesic, and watermelon vine technology, applied in the field of watermelon vine extract and its preparation, can solve problems that have not yet been reported in research

Inactive Publication Date: 2014-03-12
GUANGXI UNIV OF CHINESE MEDICINE +1
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

So far, there have been no research reports and patents on the effective parts of watermelon vine for treating rheumatoid arth

Method used

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  • Watermelon vine extract with inflammation-diminishing and pain-relieving effects, as well as preparation method and application thereof
  • Watermelon vine extract with inflammation-diminishing and pain-relieving effects, as well as preparation method and application thereof
  • Watermelon vine extract with inflammation-diminishing and pain-relieving effects, as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment Construction

[0016] One, the preparation of watermelon vine extract

[0017] Such as figure 1 As shown, take 10kg of dried and pulverized watermelon vines, ultrasonicate for 2 hours with an ethanol solution with a volume concentration of 80% according to the weight to volume ratio of 5:1, then soak for 10 days, filter, combine the filtrates, concentrate under reduced pressure to obtain a dark green extract, and freeze Dry to get 300g green powder; disperse the green powder in 5000mL deionized water according to the weight-to-volume ratio of 3:50, let it stand overnight, and centrifuge (3000rpm·min -1 ) to separate the water-insoluble green viscous solid suspension and aqueous solution; take the aqueous solution and use 3 times the volume of petroleum ether extraction, ethyl acetate, and n-butanol to extract the sample successively, and the extract is concentrated under reduced pressure respectively, and the solvent is recovered and evaporated to dryness. Petroleum ether fraction (30 g), e...

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Abstract

The invention discloses a watermelon vine extract with inflammation-diminishing and pain-relieving effects, which is a petroleum ether part prepared by alcohol precipitation and water extraction on watermelon vine. Researches discover that the extract has an excellent activity of diminishing inflammation and relieving pain, and can be applied to clinical treatment of rheumatic arthritis, rheumatoid arthritis, scapulohumeral periarthritis, bone and joint pain, cervical and lumbar pain, soft tissue pain, sprain pain and other diseases. According to the watermelon vine extract, the rich resource of the watermelon vine which is the crop waste can be sufficiently utilized, a powerful theoretical basis is provided to further research and development of medical values and clinical significance in the future, and a novel modern traditional Chinese medicinal preparation with excellent inflammation-diminishing and pain-relieving effects is expected to be provided to clinical application.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine extracts, and in particular relates to a watermelon vine extract with anti-inflammatory and analgesic effects, a preparation method and application thereof. Background technique [0002] Rheumatic disease is a kind of systemic disease that seriously endangers human health. In addition to joint pain, it can also affect other parts of the body. In mild cases, it is painful and difficult to move. In severe cases, joint deformity and limited function make it impossible to study, work and live normally , even life-threatening, brings huge physical and psychological pain to patients, and also brings heavy economic burden to families and society. According to recent survey data, there are about 400 million rheumatic patients worldwide, which is the largest group of diseases in the medical field. In China, more than 200 million people suffer from rheumatoid arthritis or rheumatoid ar...

Claims

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Application Information

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IPC IPC(8): A61K36/42A23L1/29A61P29/00A61P19/02A61P19/08A61P19/04A23L33/00
Inventor 邓家刚王硕龚小妹周小雷周丹丹戴航
Owner GUANGXI UNIV OF CHINESE MEDICINE
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