The invention discloses a medicinal liquor for rheumatism bone pain. The medicinal liquor is prepared from the following components: raw sichuan axonite root, raw radix aconiti kusnezoffii, dried ginger, herba asari, radix clematidis, flower of garden balsam, safflower, rhizoma ligustici wallichii, cassia twig, radix angelicae tuhuo, berba aristolochiae mollissimae, camphor, pine twig, notoginseng, cortex acanthopanacis, twotooth achyranthes root, frankincense, myrrh, scorpio, eupolyphaga, dogwood, ephedra, Chinese wolfberry fruit, rhizoma cibotii, ramulus mori, angelica sinensis, gentiana macrophylla, mulberry parasitism, Dongjingcao, silvery aleuritopteris, eucommia bark, nux vomica, shortstalk monkshood root, radix psammosilene, snake slough, radix dipsaci, rhizoma drynariae, radix sileris, alangium platanifolium, common clubmoss herb, pepper, cortex dictamni, sargentgloryvine stem, twotooth achyranthes root, small cortex phellodendri, trberculate speranskia herb, notopterygium andgrain wine. The above raw materials are soaked in grain wine for three months to obtain the medicinal liquor. The medicinal liquor of the invention is safe and effective and convenient to take. The effect of the medicinal liquor directly reaches the lesion, and fundamental conditioning is achieved. The medicinal liquor is effective against the pain caused by arthralgia syndrome, such as scapulohumeral periarthritis, cervical spondylosis, lumbar pain, and inconvenient legs and feet. After the medicinal liquor is taken several times, the pain is significantly relieved or disappears.