The invention discloses a duck feed for preventing bird flu and a preparation method of the feed. The duck feed comprises the following raw materials in parts by weight: 45-48 parts of rice, 18-22 parts of corn gluten meal, 10-12 parts of papaya powder, 9-11 parts of egg-shell meal, 2-4 parts of sweet potato starch, 10-12 parts of sweet potato stems, 4-6 parts of alfalfa, 1-3 parts of houttuynia cordata, 2-4 parts of isatis root, 2-4 parts of folium isatidis, 1-3 parts of hemistepta lyrata, 2-4 parts of chenopodium album linn., 1-3 parts of goosefoot, 4-6 parts of honeysuckle, 3-5 parts of folium mori, 2-4 parts of cryptotaenia japonica, 3-5 parts of gorgon fruits, 0.2-0.3 part of oleanolic acid, 0.1-0.3 part of membranous milkvetch root powder, 0.5-0.7 part of rice vinegar, 0.3-0.5 part of echinacea powder, 0.2-0.3 part of gynostemma pentaphylla powder and 1-3 parts of salt. In the formula, multiple Chinese herbal medicines such as the houttuynia cordata, the isatis root, the folium isatidis, the honeysuckle and the folium mori are added, the feed has the effects of inhibiting bacteria, resisting viruses, diminishing inflammation, removing heat and regulating immunity, has good effects in improving the immunity and preventing diseases, the bird flu can be effectively prevented, and the meat quality can be improved.