6 results about "Tumor pain" patented technology

This invention relates to the field of traditional Chinese medicine preparation technology, and particularly to a traditional Chinese medicine composition for treating cancer pain and numbness, as well as its preparation and application. This invention designs a traditional Chinese medicine composition for cancer pain and numbness, comprising: *Houttuynia cordata*, *Aconitum carmichaelii*, processed *Aconitum carmichaelii*, centipede, *Astragalus membranaceus*, *Ephedra sinica*, clove, frankincense, ephedra, menthol, and azone. The scientifically formulated combination of principal, assistant, and adjuvant herbs allows for multi-target action on both "cancer pain" (inflammation, compression, nerve infiltration) and "CIPN" (nerve damage), resulting in a superior analgesic effect, while also possessing anti-inflammatory, anti-swelling, potential tumor-suppressing, and nerve-repairing effects. The traditional Chinese medicine composition is prepared into a traditional Chinese medicine ointment, which is administered transdermally, allowing a high concentration of the drug to act directly on the lesion, avoiding the systemic side effects (addiction, constipation, etc.) associated with oral opioids. This is especially suitable for patients who cannot take oral opioids or cannot tolerate them.

This invention relates to the field of medical and health information technology and discloses a home-based pain monitoring system for malignant tumor patients. The invention collects various data related to home care of malignant tumor patients, forming pain datasets, medication datasets, and vital sign datasets. Based on these three datasets, pain risk indices, medication risk indices, and vital sign risk indices are obtained. These are then weighted and summed to obtain a comprehensive risk index. Effective correlation and collaborative analysis of multi-dimensional data improve the accuracy of the comprehensive risk index. The system determines whether to issue an alert based on the comprehensive risk index. If the comprehensive risk index reaches a threshold, three different levels of alerts (red, orange, and yellow) are issued and sent to both the patient-side interaction module and the medical staff-side interaction module. Upon receiving the alert, medical staff immediately review the patient's current condition report, analyze it, and receive timely improvement suggestions to help the patient improve their current condition, thus improving the efficiency of home care.

The application discloses a painkilling preparation containing radix scophulariae and radix aconiti and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. The preparation is a transdermal patch, which is composed of a backing layer, a drug depot layer and an anti-sticking layer. The drug depot layer contains traditional Chinese medicine active ingredients and patch auxiliaries such as pressure-sensitive adhesive and transdermal absorption accelerators. The traditional Chinese medicine active ingredients take radix scophulariae and radix aconiti as the core drug pair, and are supplemented with one or more of the following drugs: qi-regulating analgesic drugs, blood-removing qi-regulating drugs, blood-activating analgesic drugs, blood-stasis-removing analgesic drugs, warm-qi-activating cold-dispelling drugs, wind-dispelling cold-dispelling drugs and external analgesic drugs. The application is a modern traditional Chinese medicine external preparation prepared by a patch technology, and the drug can penetrate the skin and directly reach the lesion, thereby playing a therapeutic role on inflammatory pain, cancer pain and idiopathic pain. The preparation has the characteristics of large drug loading, good transdermal absorption, fast analgesic effect, long-acting effect and avoidance of oral toxicity risk.

The present application relates to the technical field of pain assessment, in particular to a tumor peace therapy pain grading assessment method based on multi-modal sensing, comprising the following steps: acquiring angular velocity and displacement direction to determine the static state, combining facial and voice features to locate the restricted period, extracting rhythm signals to identify the contradictory state, comparing the label content to extract the uncovered information, analyzing the signal features to divide the dominant channel, and modifying the label to obtain the pain grading verification label. In the present application, a static state recognition mechanism is established by fusing posture changes and signal fluctuation features, the behavior restricted time window is located by combining facial and voice features, the rhythm fluctuation information not covered by the label under the silent state is screened, the dominant channel path is constructed by extracting the signal fluctuation quantity, response sequence and synchronization relationship, the label content is compared and modified, the recognition range of the pain grading for non-extrinsic reaction state is expanded, and the coverage ability and resolution level of the label content for the rhythm behavior state are improved.

The application belongs to the field of pharmaceutical chemistry, and particularly relates to a Tropomyosin Receptor Kinase A (TrkA) inhibitor and a preparation method and application thereof, a structural formula of which is shown as formula (I); the compound provided by the application has high inhibitory activity on TrkA and good subtype selectivity. The compound has potential application in analgesic treatment, including but not limited to chronic pain caused by osteoarthritis, cancer pain, back pain and the like; the compound also has potential anticancer activity.

The present invention relates to improved method of treating breakthrough cancer pain. In particular the present invention relates to methods and devices for the treatment of breakthrough cancer pain through inhalation of tetrahydrocannabinol.