Medicine composition for treating hyperplasia of mammary glands and preparing technology

A technology for breast hyperplasia and composition, which is applied in drug combinations, medical preparations containing active ingredients, anti-tumor drugs, etc., can solve problems such as unpleasantness and easy recurrence of patients, and achieves reduction of adverse reactions, slow dissolution and effect. lasting effect

Inactive Publication Date: 2006-08-09
谢黎
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ovarian tumors currently have no ideal medicine in Western medicine, and surgery is often used f

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0054] Experimental example 1 Process technical conditions optimization

[0055] 1. On the basis of the original preparation process, investigate the amount of water added:

[0056] According to the production process of Hongjin Xiaojie Concentrated Pills, take one-eighth of the prescription amount of medicinal materials, grind them into coarse powder, add 6, 8, 10, and 12 times the amount of water to decoct three times, the first time for 2 hours, the second time The second time was 1.5 hours, and the third time was 1 hour. The decoction was combined, filtered, and concentrated to a dry paste. The yield of the paste and the extraction rate of n-butanol were investigated. The results are shown in Table 1:

[0057] Amount of water added (times)

Paste output (g)

Paste yield (%)

Butanol extraction rate (%)

6

8

10

12

40.60g

42.35g

44.10g

44.80g

11.6

12.1

12.6

12.8

1.423

1.515

1.555

1.5...

experiment example 2

[0066] Experimental example 2 Pilot test data

[0067] The three batches of pilot test data adopt the optimized process, and the three batches of samples are produced in the pilot test with 10 times the amount of the prescription. The obtained data are shown in Table 2:

[0068] batch number

experiment example 3

[0069] Experimental example 3 Pilot product inspection

[0070] Three batches of pilot products are inspected by "Chinese Pharmacopoeia" 2000 edition one pill item (appendix IA) requirement, and the results are shown in Table 3:

[0071] batch number

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PUM

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Abstract

The invention discloses a drug combination for curing proliferation of mammary gland and the preparing method thereof, composed of the ten drugs: Radix Notoginseng, Rhizoma Cyperi, Common Dysosmatis Rhizome and Root, Pillbug Armadillidium, Black ant, Kadsura longipedunculata Finet, Paederia scandens(Lour.)Merr, Wild Buckwheat Rhizome, Campglotroopis hirtella schindl, and Chinese Thorowax Root and its producing process: taking Radix Notoginseng, Rhizoma Cyperi, Common Dysosmatis Rhizome and Root, Pillbug Armadillidium, and black ant and crushing into fine powder separately, mixing uniformly, and sterilizing and reserving; decocting the rest with water, separately, and combining the decoction, filtering, concentrating the filtrate into ointment with relative density 1.05-2.05, spray-drying or concentrating to a proper amount, mixing the ointment with the mixed powder and making concentrated water pills. It is applied to curing proliferation of trabecula of mammary gland, muscular tumors of uterus, and ovarium cyst, and has very good efficacies of comforting the liver and regulating Qi, softening hard and dispelling node, promoting the blood circulation and removing blood stasis, detumescence and stopping pain.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation process thereof, in particular to a pharmaceutical composition for treating mammary gland hyperplasia and a preparation process thereof. Background technique [0002] Breast hyperplasia, uterine fibroids, and ovarian cysts are all caused by long-term qi stagnation, blood stasis, and endocrine disorders that lead to estrogen (E2R, PR) stasis in the uterus, ovaries, and breasts to stimulate local tissue proliferation. Patients often present with dizziness, fatigue, backache and abdominal distension, breast tenderness, irregular menstruation with abnormal color, excessive leucorrhea with peculiar smell, rough and dull skin, and complications such as uterine bleeding in severe cases. [0003] Western medicine commonly used for the treatment of hyperplasia of mammary glands has hormones, iodine preparations and other symptomatic drugs. Traditional hormone preparations mainly use male h...

Claims

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Application Information

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IPC IPC(8): A61K36/89A61K35/64A61K9/20A61P15/14A61P15/00A61P35/00
Inventor 谢黎
Owner 谢黎
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