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Effervesce agent for treating headache, and preparation method

A technology of effervescent tablets and dosage excipients, applied in the field of medicine, which can solve the problems of slow dissolving speed of granules, inconvenient taking and carrying, and poor taste of oral administration, etc., and achieves the advantages of reducing the irritating smell of drugs, convenient administration, and small molecular weight Effect

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently reported Chinese patent medicine for treating headaches is Zhengtian Wan, which is a combination of Chinese and Western medicines. Its mechanism is to promote blood circulation and remove blood stasis, and it is equipped with Western medicine analgesics. Internal injury headache, blood deficiency and blood stasis liver yang headache, the effect is not good
[0003] At present, there are many traditional Chinese medicines for treating headaches, and the dosage forms are mostly granules and granules. Granules have disadvantages such as slow dissolution rate, large dosage, poor taste when taken orally, and inconvenient taking and carrying.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Proportionally take 6.75g of Angelica, 6.75g of Chuanxiong, 5.4g of Radix Paeoniae Alba, 5.4g of Rehmannia Rehmanniae, 13.5 parts by weight of Uncle Teng, 13.5g of Miltonia Spatholobus, 13.5g of Prunella vulgaris, 13.5g of Cassia Seed, 13.5g of Mother of Pearl, and 6.75g of Yuanhu , Asarum 1.34g, boil the above drugs with water for 3 times, 1 hour each time, combine the decoction, concentrate an appropriate amount, add 2 times the amount of ethanol, let it stand for 24 hours to precipitate, take the supernatant and concentrate it into a paste, the relative density is 1.3 ~1.4, dried or spray-dried, pulverized to obtain medicinal powder for later use.

Embodiment 2

[0059] Proportionally take 4g of Angelica, 4g of Chuanxiong, 2g of Radix Paeoniae Alba, 2g of Rehmannia Rehmanniae, 10g of Uncle Teng, 10g of Miltonia Spatholobus, 10g of Prunella vulgaris, 10g of Cassia Seed, 10g of Mother of Pearl, 4g of Rhizoma Rhizoma Radix, 0.5g of Asarum, and boil the above drugs for 5 Once, each time for 2 hours, combine the decoction, concentrate an appropriate amount, add 4 times the amount of ethanol, let it stand for 18 hours to precipitate, take the supernatant and concentrate it into a paste with a relative density of 1.1 to 1.5, dry or spray dry, and pulverize to obtain The powder is ready for use.

Embodiment 3

[0061] Proportionally take 9g of Angelica, 9g of Chuanxiong, 8g of Radix Paeoniae Alba, 8g of Rehmannia Rehmanniae, 15g of Uncle Teng, 15g of Spatholobus Spatholobus, 15g of Prunella vulgaris, 15g of Cassia Seed, 15g of Mother of Pearl, 9g of Rhizoma Rhizoma Rhizome, 2g of Asarum, add water to boil 3 times , 1 hour each time, combine the decoction, concentrate an appropriate amount, add 2 times the amount of ethanol, let it stand for 36 hours to precipitate, take the supernatant and concentrate it into a paste with a relative density of 1.3-1.4, dry or spray dry, and pulverize to obtain a medicinal powder spare.

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PUM

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Abstract

A Chinese medicine in the form of effervescent tablet for treating headache is prepared from 11 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, white peony root, prunella spike, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an effervescent tablet for treating headache made from traditional Chinese medicine and a preparation method thereof. Background technique [0002] Angioneurotic headache is a common disease. Although some Chinese and Western medicines are available, the effect is not very satisfactory, especially for the treatment of liver-yang headache of blood deficiency and blood stasis type, which has not been reported in the literature at home and abroad. . The commonly used Western medicine for the treatment of headaches has ergotamine caffeine, which is a vasodilator and is only suitable for cerebral arterial ischemic phlegm disease. In addition, the mechanism of action of flunarizine capsules produced in 1988 is to selectively inhibit the entry of calcium into cells, so as to reduce the contraction of veins. The currently reported Chinese patent medicine for treating headaches is Zhengtian Wan,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/20A61K9/46A61P25/04A61K35/56A61K35/618
Inventor 李永强郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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