Reagent kit for detecting 2-diabetes serum mark in Chinese people

A biologically active and molecular technology, applied in the field of detection kits for new serum markers of type 2 diabetes in China, can solve the problems of rare serum markers of diabetes and interference with the separation and identification of low-abundance proteins.
CN1928557AInactive Publication Date: 2007-03-14THE INST OF BASIC MEDICAL SCI OF CHINESE ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE INST OF BASIC MEDICAL SCI OF CHINESE ACAD OF MEDICAL SCI
Publication Date
2007-03-14
Estimated Expiration
Not applicable · inactive patent
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Abstract

The invention relates to the reagent box to detect new serum of II-type diabetes. Specially, it applies the serum of galectin-1 and corresponding express-level in patient to modify the box. It also relates to the application in diagnosis and treatment of galectin-1.
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Description

technical field

[0001] The present invention relates to a serum marker of type 2 diabetes. The serum marker is Galectin-1, that is, soluble galactosidase-binding lectin protein type 1 (lectin, galactoside-binding, soluble, 1). The present invention also relates to a detection kit designed using the identified marker galectin-1 and its expression level changes in patients. Further, the present invention also relates to the role of the serum marker in the diagnosis of diabetes, and as a target for drug design for diabetes treatment. Background technique

[0002] As we all know, type 2 diabetes is a complex trait disease controlled by multiple genes, with obvious genetic predisposition. At present, it is believed that related protein molecules involved in insulin signal transduction pathway, glucose transport pathway, glycogen synthesis pathway, fatty acid absorption and synthesis, and adipocyte differentiation pathway may be related to the occurrence of diabetes. Research on...

Claims

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