The treatment of respiratory disease
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SOSEI R&D LTD
- Publication Date
- 2007-04-18
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
field of invention
[0001] The present invention relates to the treatment of respiratory diseases. Background of the invention
[0002] Glycopyrrolate has been known for many years to be a potent antimuscarinic agent. It has been used for several indications and delivered by many different routes. Recently, it has been used as an injection to reduce secretion during anesthesia and as an oral product for the treatment of gastric ulcers. One of the earliest indications of its use in airway diseases was in 1984, where it was shown to have a marked effect on bronchiectasis. Since then, many studies have been done to prove its potential utility.
[0003] Schroeckenstein et al., J. Allergy Clin. Immunol., 1988;82(1):115-119, disclose the use of an aerosol formulation of glycopyrronium bromide for the treatment of asthma. A single metered dose of aerosol glycopyrronium bromide achieved bronchodilation over a 12-hour period.
[0004] Leckie et al., Exp. Opin. Invest. Drugs, 2000...