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Chinese-medicinal contraceptive liquid and its production

A technology of traditional Chinese medicine and medicament, which is applied to the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of disturbing the human endocrine system, complicated preparation process and high drug cost, and achieves reliable contraceptive effect and simple preparation process. , the effect of high drug purification

Inactive Publication Date: 2007-06-20
孔庆建
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the contraceptive drugs used by our people in daily life are mainly oral contraceptive drugs, which are called western medicine in medicine and are very effective in contraception. Absorbed by other organs, the toxic and side effects are very harmful to the body, and it will also disturb the human endocrine system. The preparation process of oral contraceptives is complicated and the drug cost is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0029] [Experimental Example 1] Acute oral toxicity test in mice:

[0030] Tested substance: the product produced by the present invention is brown liquid, weighing 1g per 1ml of tested mouse.

[0031] Experimental animals: 20 ICR mice, half male and half female, weighing 18-22 g, were provided by the Experimental Animal Center of Shaanxi Academy of Traditional Chinese Medicine, Class I animals (No. 08-24 of Yidongzi).

[0032] Animal room environment: temperature: 25-27°C, relative humidity 45%-55%, the animal room meets the experimental standards.

[0033] Preparation of the test substance: Take 1ml of the original solution on the test day, and prepare a 40% solution with distilled water for later use.

[0034] Test method: Before the test, the mice were fasted for 16 hours, and they were not limited to drinking water. Weighed during the test, administered the test substance to the mice at a dose of 8000mg / kg·bw, and the dosage was 0.2ml / 10g·bw, and closely observed the an...

experiment example 2

[0039] [Experimental Example 2] Vaginal mucosa irritation test:

[0040] Tested substance: the traditional Chinese medicine contraceptive solution produced by the present invention is brown liquid.

[0041] Experimental animals: 18 SD rats, female, weighing 180-220 g, were provided by the Experimental Animal Center of Shaanxi Academy of Traditional Chinese Medicine, first-class animals.

[0042] Animal room environment: temperature: 25-27°C, relative humidity 45%-55%. The animal room complies with national standards.

[0043] Dosage of the test substance: Measure 10ml of the original solution, adjust it to a 40% solution with distilled water for use, 0.2ml / piece.

[0044] Test method: 18 non-estrous rats were randomly divided into three groups, namely the test substance group, the vehicle group and the blank control group, with 6 rats in each group. During the test, the animals were fixed in a supine position. The test substance group was injected with 0.2ml of the test sub...

experiment example 3

[0049] [Experimental example 3] skin allergy test:

[0050] Tested substance: the traditional Chinese medicine contraceptive solution produced by the present invention is brown liquid, and the weight of every 1ml of tested substance is 1g. Stock solution for preparation. Positive control substance: 2,4-dinitrochlorobenzene (DNCB), produced by Beijing Xingjin Chemical Factory, batch number 20020522.

[0051] Experimental animals: 30 guinea pigs, half female and half male, weighing 280-320 g, were provided by the Experimental Animal Center of Xi'an Jiaotong University School of Medicine, first-class animals.

[0052] Animal room environment: temperature: 25-27°C, relative humidity: 45%-55%. The animal room complies with national standards.

[0053] Test method: The test guinea pigs were randomly divided into three groups, 10 in each group, half female and half male, which were respectively the test substance group, negative control group and positive control group.

[0054]S...

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PUM

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Abstract

An exterior-applied Chinese contraceptive medicine in the form of liquid is prepared from 8 Chinese-medicinal materials including the volatile oil of carrot seed, rhubarb, Chinese prickly ash, menthol, etc. Its preparing process is also disclosed.

Description

1. Technical field [0001] The invention relates to a contraceptive drug and a preparation process thereof, in particular to a traditional Chinese medicine contraceptive liquid and a preparation process thereof, belonging to the technical field of medicines. 2. Background technology [0002] The implementation of family planning is a basic national policy of our country. From a practical point of view, my country's population policy is in line with the actual situation of our country, and has set a model for countries in the world in the implementation of family planning work. For a long time, people have made unremitting efforts and pursuits in the two physiological processes of conception and contraception, not only to achieve prenatal and postnatal care, but also not to affect people's quality of life due to poor childbearing time. With the continuous improvement of people's living standards, the concept of fertility is also constantly changing, emphasizing not only concep...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61P15/18
Inventor 孔庆建
Owner 孔庆建
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