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Chinese medicinal preparation with heat-clearing toxin-removing function and its preparation process

A traditional Chinese medicine preparation, a technology for clearing heat and detoxification, which is used in pharmaceutical formulations, antiviral agents, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2007-07-04
SICHUAN JINHUI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to: provide a traditional Chinese medicine preparation for clearing away heat and detoxification and its preparation method; the present invention aims at the prior art and provides dispersible tablets with good disintegration and high bioavailability, especially suitable for infants, the elderly and Take it for patients who have difficulty in swallowing medicines; the capsule and soft capsule preparations provided by the invention solve the problem of medicine being unstable when exposed to heat and humidity, and can also cover up the bad taste and smell of medicines, which can increase stability and improve bioavailability effect; the tablet provided by the invention has low production cost and meets the needs of clinical multiple drug selection

Method used

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  • Chinese medicinal preparation with heat-clearing toxin-removing function and its preparation process

Examples

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Effect test

Embodiment 2

[0009] Example 2 of the present invention: bear bile 11.1g, rhubarb 222.2g, catechu 111.1g, borneol 22.2g, coptis 166.7g, fragrance ink 33.4g, xuanming powder 22.2g

[0010] Take the Xuanming powder, add 2.5 times the amount of water to heat to dissolve, filter, and use the filtrate for later use; take half of the rhubarb and Hu Huanglian and add water to decoct three times, each time 8 times the amount of extraction for 1 hour, combine the decoction, filter, the filtrate and Xuanming The powder and liquid are combined and concentrated to a thick paste with a relative density of 1.30-1.32 at 50℃~60℃; catechu, fragrant ink and remaining rhubarb are mixed with 75% ethanol in an appropriate amount, stuffed for 1 hour, dried at 60~80℃, and crushed into Fine powder, add the above thick paste, mix well, dry, pulverize into fine powder, add dextrin and microcrystalline cellulose (dextrin dosage accounts for 12.5% ​​of the total weight of the particles, and the dosage of microcrystalline ...

Embodiment 3

[0011] Example 3 of the present invention: bear bile 11.1g, wine rhubarb 222.2g, catechu 111.1g, borneol 22.2g, coptis 166.7g, fragrance ink 33.4g, xuanming powder 22.2g

[0012] Take the Xuanming powder, add 2.5 times the amount of water to heat to dissolve, filter, and use the filtrate for later use; take half of the rhubarb and Hu Huanglian and add water to decoct three times, each time 8 times the amount of extraction for 1 hour, combine the decoction, filter, the filtrate and Xuanming The powder and liquid are combined and concentrated to a thick paste with a relative density of 1.30-1.32 at 50℃~60℃; catechu, fragrant ink and remaining rhubarb are mixed with 75% ethanol in an appropriate amount, stuffed for 1 hour, dried at 60~80℃, and crushed into Fine powder, add the above thick paste, mix well, dry, pulverize into fine powder, add 4% croscarmellose sodium, 60% ethanol, make soft material with appropriate amount, granulate, crush bear bile and borneol into fine powder Then,...

Embodiment 4

[0013] Example 4 of the present invention: bear bile 11.1g, wine rhubarb 222.2g, catechu 111.1g, borneol 22.2g, coptis 166.7g, fragrance ink 33.4g, xuanming powder 22.2g

[0014] Take the Xuanming powder, add 2.5 times the amount of water to heat to dissolve, filter, and use the filtrate for later use; take half of the rhubarb and Hu Huanglian and add water to decoct three times, each time 8 times the amount of extraction for 1 hour, combine the decoction, filter, the filtrate and Xuanming The powder and liquid are combined and concentrated to a thick paste with a relative density of 1.30-1.32 at 50℃~60℃; catechu, fragrant ink and remaining rhubarb are mixed with 75% ethanol in an appropriate amount, stuffed for 1 hour, dried at 60~80℃, and crushed into Fine powder, add the above thick paste, mix well, dry, crush into fine powder, crush bear bile and borneol into fine powder, mix evenly, according to the powder: soybean oil = 1:1.2, add soybean oil, and then add 4% beeswax, Mix an...

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Abstract

The invention discloses a Chinese medicinal preparation for treating heat clearing and detoxicating and its preparing process, wherein the preparation mainly comprises bear's gall 11.1g, wine-treated rhubarb 222.2g, black catechu 111.1g, borneol 22.2g, picrorhiza rhizome 166.7g, frankincense 33.4g and powder of natrii sulfas exsiccatus 22.2g. The preparation has good effect in treating acute upper respiratory tract infection.

Description

Technical field [0001] The invention relates to a heat-clearing and detoxifying Chinese medicine preparation and a preparation method thereof, and belongs to the technical field of Chinese medicine. Background technique [0002] Acute upper respiratory tract infections, including viral and bacterial upper respiratory tract infections, are clinically common and frequently-occurring diseases, and belong to the category of exogenous fever in traditional Chinese medicine. It has the characteristics of acute onset, short course of disease, rapid spread, and visible in four seasons. Although there are many kinds of Chinese and Western medicines on the market for the treatment of such diseases, because of the widespread side effects of antibiotics, there are few Chinese medicine preparations with definite antipyretic effect. "Wanying Ding" (Huhuanglian 100g, Huanglian 100g, Catechu 100g, Borneol 6g, Fragrant Ink 200g, Bear Gallbladder 20g, etc.) were originally traditional and ancient p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K9/00A61K9/16A61K9/20A61K9/48A61P11/00A61P31/04A61P31/12A61K35/413A61K31/045
Inventor 何祖新
Owner SICHUAN JINHUI PHARMA
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