Topical compositions comprising hydroxy acids and cannabinoids for skin care

a technology of cannabinoids and hydroxy acids, applied in the direction of anhydride/acid/halide active ingredients, oil/fat/waxes non-active ingredients, plant/algae/fungi/lichens ingredients, etc., can solve the problems of skin aging and temporary relief, and achieve the effect of improving a skin condition

Inactive Publication Date: 2018-01-25
KANNAINNOVATIONS LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sunlight is a major cause of skin aging.
While treatment with moisturizers and steroid creams may temporarily control skin disorder and aging symptoms by reducing inflammation and smoothing wrinkles, the relief is only temporary.
There is no known cure for dermatitis, and systemic side effects prevent long term treatment of chronic dermatological conditions with steroids.

Method used

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  • Topical compositions comprising hydroxy acids and cannabinoids for skin care
  • Topical compositions comprising hydroxy acids and cannabinoids for skin care
  • Topical compositions comprising hydroxy acids and cannabinoids for skin care

Examples

Experimental program
Comparison scheme
Effect test

example 1

on of Topical Compositions Comprising Alpha Hydroxy Acid and Cannabinoids

[0070]A. Preparation of Alpha Hydroxy Acid Compositions in Alcohol

[0071]5.0 grams of lactic acid, glycolic acid, citric acid, mandelic acid, benzylic acid, malic acid, tartaric acid or gluconolactone are dissolved in propylene glycol. The mixture is shaken and 4.0 grams of hydroxypropylcellulose are slowly added to the mixture to avoid clamping.

[0072]B. Preparation of Cannabinoid Compositions

[0073]Trichomes and leaves are collected from Cannabis sativa and Cannabis indica, dried in air after harvest, finely ground and dissolved into a solvent in a volume ratio of 1:5. The solution is heated to evaporate the solvent and the dry mixture is dissolved in hemp oil.

[0074]C. Preparation of Topical Compositions

[0075]The solution of alpha hydroxy acid is added to the hemp oil composition containing the cannabinoids and the mixture is agitated and formulated into compositions for topical administration.

example 2

on of Topical Compositions Comprising Alpha Hydroxy Acid and Hemp Oil

[0076]5.0 grams of lactic acid, glycolic acid, citric acid, mandelic acid, malic acid, tartaric acid or gluconolactone are dissolved in hemp oil and the solution is formulated into compositions for topical administration.

example 3

of Dermatitis

[0077]20 subjects with severe dermatitis are divided into four groups, 5 subjects per group. The subjects are instructed to topically apply a lotion two times daily for two weeks. Group one is treated for two weeks with a lotion containing hydroxy acids. Group two is treated for two weeks with a lotion containing cannabinoids. Group three is treated for two weeks with a lotion containing hydroxy acids and cannabinoids in hemp oil prepared according to Example 1. Group four is treated for two weeks with a lotion containing hydroxy acids and hemp oil prepared according to Example 2. The effects of the different treatments are evaluated after two weeks.

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Abstract

The present invention relates to compositions and methods for the prevention and treatment of skin disorders and for the rejuvenation of the skin. In particular, the application describes topical compositions and methods of treatments comprising the combined use of one or more cannabinoids and one or more hydroxy acids in a suitable carrier.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims the benefit of priority from U.S. Provisional Application No. 62 / 203,698, filed Aug. 11, 2015, the content of which is incorporated by reference in its entirety.FIELD OF THE INVENTION[0002]The present invention relates to the use of hydroxy acids and cannabinoids for skin care.BACKGROUND OF THE INVENTION[0003]The skin is the largest organ of the body, with a surface area of 18 square feet. In the epidermis, the keratinocytes produce keratin, a protein that gives skin its strength and flexibility and waterproofs the skin surface. Collagen and elastic fibers in the dermis give strength to the skin. The skin is continuously exposed to changes in the external environment, including oxidative insults, heat, cold, UV radiation, injury, and mechanical stresses. The stratum corneum, composed of terminally differentiated keratinocytes, constitutes the natural barrier that prevents loss of water and penetration of infectious...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/97A61K47/44A61K31/194A61K31/19A61K36/185A61K45/06A61K9/00A61K8/92A61K8/73A61K8/365A61Q19/08A61K8/34A61K31/192A61K31/366A61K47/12
CPCA61K47/12A61K31/194A61K45/06A61K9/0014A61K8/922A61K8/731A61K8/365A61Q19/08A61K8/97A61K8/345A61K31/192A61K47/44A61Q17/04A61K31/352A61K36/185A61K31/366A61K31/19A61K8/9789A61K2300/00
Inventor GHALILI, BABEKMCGOVERN, KEVIN
Owner KANNAINNOVATIONS LLC
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