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Optoelectronic system and apparatus for connection to biological systems

a technology of biological systems and optoelectronic systems, applied in the field of optoelectronic structures capable of connecting to biological systems, can solve the problems of lack of spatial precision in either stimulating or detecting individual neurons or isolated regions within neural tissue, and the difficulty of implanting and maintaining probes without complications and degradation

Active Publication Date: 2018-03-06
NAT TECH & ENG SOLUTIONS OF SANDIA LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention relates to a biological probe structure that can be used for detecting, treating, and assessing biological targets. The structure includes a hermetically sealed unit that can receive and transmit optical and electrical signals. It can be implanted subcutaneously and interrogated externally using an external transceiver unit. The structure has one or more emitters and detectors that can transmit and receive optical signals. The invention features a self-contained structure that can be embedded in a target region and a system for connecting to a biological target that includes an apparatus and an external transceiver unit. The invention also provides a method of detecting and treating a biological target by providing external optical inputs to the structure.

Problems solved by technology

However, these methods are limited in spatial and temporal characteristics.
For instance, some probes are large (e.g., on a millimeter scale) and, therefore, lack spatial precision in either stimulating or detecting individual neurons or isolated regions within neural tissue.
In another instance, some probes can be difficult to implant and maintain without complications and degradation both in the target tissue and within the biological system.

Method used

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  • Optoelectronic system and apparatus for connection to biological systems
  • Optoelectronic system and apparatus for connection to biological systems
  • Optoelectronic system and apparatus for connection to biological systems

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Embodiment Construction

[0038]The present invention features a system that provides an implantable, completely insulated system that does not expose any non-beneficial electrical connections to the tissue, either on external surfaces or encased within polymeric substrates of the system. Non-beneficial (e.g., non-therapeutic) electrochemical reactions can lead to degradation of the interconnections, and exposed electrodes in conventional neural probes can ultimately limit the lifetime and applicability of such systems. Power and data are delivered and extracted from the system through optical coupling, either through a fiber or free-space means. This allows an external unit (e.g., an external transceiver unit) to provide the needed power and telemetry needs for the experiment and / or medical application.

[0039]FIG. 1A shows an exemplary system including an apparatus 100 and an external unit 150. As can be seen, an optical connector 120 (e.g., an optical fiber) terminated by an optical collector 110 is embedde...

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Abstract

The present invention relates to a biological probe structure, as well as apparatuses, systems, and methods employing this structure. In particular embodiments, the structure includes a hermetically sealed unit configured to receive and transmit one or more optical signals. Furthermore, the structure can be implanted subcutaneously and interrogated externally. In this manner, a minimally invasive method can be employed to detect, treat, and / or assess the biological target. Additional methods and systems are also provided.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims the benefit of U.S. Provisional Application No. 61 / 839,264, filed Jun. 25, 2013, which is hereby incorporated by reference in its entirety.STATEMENT OF GOVERNMENT INTEREST[0002]This invention was made with Government support under contract no. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation. The Government has certain rights in the invention.FIELD OF THE INVENTION[0003]The present invention relates to optoelectronic structures capable of connecting to biological systems. In particular, the structures of the invention include a hermetically sealed unit configured to receive and transmit one or more optical and / or electrical signals. These structures are configured to be coupled optically to one or more components to allow an implanted structure to be interrogated externally (e.g., by way of an external transceiver unit). Additional devices, apparatuses, systems, and methods including ...

Claims

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Application Information

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Patent Type & Authority Patents(United States)
IPC IPC(8): A61B5/1455A61B5/1459A61B5/1473
CPCA61B5/1459A61B5/1473A61B2560/0214A61B5/6848A61B5/6868A61B5/0084A61B2562/0233A61B2562/185A61B5/24
Inventor OKANDAN, MURATNIELSON, GREGORY N.
Owner NAT TECH & ENG SOLUTIONS OF SANDIA LLC
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