The invention relates to a clinical preoperative eye cleaning device, which effectively solves the problem that the operation is inconvenient when a medical worker cleans eyes. Comprising a control box, a square groove is formed in the front side wall of the control box, a sliding plate is arranged in the control box, a push plate located above the sliding plate is arranged in the control box, an extrusion block is arranged at the front end of the push plate, a pressing block located in front of the extrusion block is arranged in the control box, a sliding groove is formed in the pressing block, and the sliding groove is slidably connected with a sliding rod which is slidably connected with the push plate. A sliding groove is formed in the side wall of the control box, a transverse shaft is fixed to the pressing block, inserted into the sliding groove and provided with an arc-shaped plate through a connecting rod, a liquid storage box is arranged in the control box, the lower end of the liquid storage box communicates with a water pump, a guide rod is arranged at the front end of the sliding plate, a kidney-shaped groove is formed in the guide rod, and a guide groove is formed in the rear side wall of the control box; the rear ends of the cleaning cylinders are inserted into the guide grooves, the front end of the right cleaning cylinder penetrates through the kidney-shaped groove, and the cleaning cylinders communicate with the water pump. The device is ingenious in conception and convenient to use.