The invention provides a chemical fertilizer stacking frame capable of preventing chemical fertilizer from being affected with damp. The chemical fertilizer stacking frame capable of preventing chemical fertilizer from being affected with damp comprises a cabinet body, a sliding structure which is arranged on the inner side wall of the cabinet body, and comprises a sliding groove, a limiting holeand a rotating groove, an air exchange structure which is installed in the cabinet body, and comprises a first air vent, a second air vent, an air blower, a communicating pipe and an air duct, a supporting structure which is slidably connected into the sliding groove, and comprises a supporting plate, a rotating shaft, a rolling wheel, an inner sliding plate, an inner rotating shaft, a connectingpiece and a limiting groove, and a locking structure which is installed in the supporting plate, and comprises an inner sliding groove, a sliding block, a telescopic rod, a limiting column, a storagegroove, limiting teeth, a torsion spring and a spring. The chemical fertilizer stacking frame capable of preventing chemical fertilizer from being affected with damp has the advantages of being safe in stacking and beneficial to ventilation.