Integrated capillary electrophoretic chip scanning analysis system and method

A capillary electrophoresis and analysis system technology, applied in the field of integrated capillary electrophoresis chip scanning analysis system, can solve the problems of bulky, slow, one-time detection, complex structure, etc., and achieve the effect of small size, convenient operation and simple system structure

Inactive Publication Date: 2008-11-12
SHANGHAI UNIV
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Problems solved by technology

The traditional ICE chip scanning analysis system is based on the photomultiplier tube (PMT) photoelectric conversion confocal scanning detection device to scan and detect the ICE chip, and the detection signal is input to the computer through the signal processor for analysis and processing. The speed is slow, and only the fluorescent signal emitted by one point of the ICE chip can be detected at a time

Method used

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  • Integrated capillary electrophoretic chip scanning analysis system and method
  • Integrated capillary electrophoretic chip scanning analysis system and method

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Embodiment Construction

[0025] A preferred embodiment of the present invention is described in detail as follows in conjunction with accompanying drawing:

[0026] see figure 1 , with ARM embedded processor (CY-ARM4510B) 1 and 32-bit DSP processor DM642 (5) collaborative work as the core design. The system is CY-ARM4510B (1) extended color LCD 2, used for various display of the instrument; extended keyboard and mouse 3, used for various man-machine operations; extended Ethernet port (ETHERNET PORT) module, used for accessing the network It communicates with the central computer of the hospital and the virus / gene library on the network; in addition, there are reset circuit (RESET), real-time clock (CLOCK) modules, etc. In DM642 5, the CPU is directly connected to the first-level program cache and the first-level data cache. The two caches are 16K-Byte respectively, and they work in the full-speed access state of the CPU. The secondary cache is 256K-Byte. The system expands 4M-Byte flash memory (FLA...

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Abstract

This invention relates to an integrated capillary electrophoresis chip scanning and analysis system and a method including a scan test device connected with a test signal process and analysis system, in which, the scan test device is a CCD camera head, the test signal process and analysis system includes: a DSP processor connecting to a FLASH via its EMIF interface, a SDRAM data storage and a FIFO buffer chip, the CCD camera head is connected with the FIFO buffer chip via an A / D converter, the DSP processor is connected with an inserted processor via its HPI host orifice, which is connected with a LCD display, keyboard and mouse.

Description

technical field [0001] The present invention relates to a device and method for signal detection of biological chips, especially an integrated capillary electrophoresis chip scanning analysis system and method Background technique [0002] Biochips can be divided into microarray DNA chips and microfluidic integrated capillary electrophoresis chips (Lab-on-a-chip). The extraction, separation, labeling, hybridization and signal detection of detection samples in DNA chip technology are carried out on different technical platforms. Lab-on-a-chip synthesizes all these steps on a technical platform, realizing the integration, miniaturization and automation of sample processing, purification, reaction, detection and analysis. The integrated capillary electrophoresis chip (integrated capillary electrophoresis, ICE) has important application prospects in the field of medical and biological analysis. The whole system can be widely used in biochemistry, molecular biology, clinical med...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/00G01N33/48G06K9/00
Inventor 马文丽郑文岭刘莉莉
Owner SHANGHAI UNIV
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