Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Bursopoietin extracting method and its use in disease treating and immune

An extraction method and technology of bursalin, applied in the extraction method and its application in disease treatment and immunity, can solve the problems of limited application, achieve no drug residue, improve the cure rate, and promote the body's humoral immunity and cellular immunity. The effect of the level of immune response

Inactive Publication Date: 2009-06-10
王爱华 +1
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The immune enhancement effect is good, but due to However, its application in veterinary clinics is greatly limited.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Bursopoietin extracting method and its use in disease treating and immune
  • Bursopoietin extracting method and its use in disease treating and immune
  • Bursopoietin extracting method and its use in disease treating and immune

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] Extraction process of the present invention is:

[0034] Take 80g of healthy bursa, add an appropriate amount of 1N glacial acetic acid application solution, and homogenize at 20000r / min for 3min to make it into a paste. Shake on a horizontal oscillator for 1.5h to 2h, centrifuge at 4500r / min at 4°C for 60min, take the supernatant, put it in a boiling water bath for 20min, centrifuge again, take the supernatant and filter. The filtrate was concentrated to about 40ml under reduced pressure with a rotary evaporator between 60°C and 70°C. The concentrated solution was centrifuged at 20,000 g at a high speed for 30 minutes at 4°C to obtain about 20 ml of supernatant, which was the crude extract. Pass the crude extract through a G-50 Sephadex column, elute with 1N acetic acid, collect CuSO 4 React positive fraction with 7.5% NaHCO 3 Adjust the pH value to neutral, which is the tissue extract-bursalin.

[0035] The present invention is mainly used in:

[0036] 1. Used al...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a bursin extracting method and its application to curing disease and immunity, having important value in application in the aspects of heightening organismal immunity and acting as immunoenhancer, heightening effect of vaccine, etc., and able to heighten body fluid and cell immune functions of mammal at the same time. It can be used to prevent and cure infectious diseases and young animal diseases singly or together with other drugs such as antivirus and antibacterial drugs or immunomodulators, also be applied to animal vaccine as adjuvant or immunoenhancer to strengthen the disease-resistant ability and immunoresponse ability to peculiar antigens, thus heightening the immune effect.

Description

1. Technical field: [0001] The invention relates to an immune preparation for livestock and poultry, in particular to a method for extracting bursal and its application in disease treatment and immunity. 2. Background technology: [0002] The occurrence of infectious diseases, especially viral infectious diseases, is an important factor affecting the development of animal husbandry. After most pathogenic microorganisms invade the body, they can cause damage to the immune organs, weaken the body's immune function, weaken the disease resistance, and further develop the disease. , At the same time, it causes secondary infection and immune failure, causing huge losses to the aquaculture industry. Relying solely on vaccine immunization, on the one hand, due to the failure of immunity caused by various reasons, on the other hand, due to the limitation of the immune protection rate of the vaccine itself, it is difficult to completely prevent the occurrence of infectious diseases. T...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07K1/14C07K5/08A61K38/06A61P37/04A61P31/12A23K1/16A23K20/00A61K9/20
Inventor 王爱华靳亚平周乐李键
Owner 王爱华
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com