77results about How to "Simple chemical structure" patented technology

The invention relates to a ferulic acid shown in a general formula (I) and the application of derivatives thereof to pesticides. When used as novel anti-phytoviral agents, the derivatives can well inhibit tobacco mosaic viruses, pepper viruses, tomato viruses, sweet potato viruses, potato viruses, melon viruses, maize dwarf mosaic viruses and the like, and effectively prevent and control the virus diseases of various crops such as tobacco, peppers, tomatoes, melons, grains, vegetables, beans and the like, and are particularly suitable for preventing and controlling tobacco mosaic. Meanings of each group are shown in specifications.

The invention relates to a bursin extracting method and its application to curing disease and immunity, having important value in application in the aspects of heightening organismal immunity and acting as immunoenhancer, heightening effect of vaccine, etc., and able to heighten body fluid and cell immune functions of mammal at the same time. It can be used to prevent and cure infectious diseases and young animal diseases singly or together with other drugs such as antivirus and antibacterial drugs or immunomodulators, also be applied to animal vaccine as adjuvant or immunoenhancer to strengthen the disease-resistant ability and immunoresponse ability to peculiar antigens, thus heightening the immune effect.

The invention discloses an LCD device and a manufacture method thereof. The manufacture method comprises the following steps: first of all, providing a first substrate and a second substrate parallel to each other; secondly, blending and sealing a liquid crystal coordination compound and a dielectric anisotropic negative type liquid crystal material between the first substrate and the second substrate, further the liquid crystal coordination compound is an Acrylic monomer with a single-functional base; and then polymerizing the liquid crystal coordination compound to form a first coordination layer and a second coordination layer on the first substrate and the second substrate respectively. Since the liquid crystal coordination compound only has the single-functional base, the chemical construction is simpler, the price is low, and the vertical coordination is stable.

The invention discloses a polyurethane waterproof coating material, which comprises a component A and a component B, wherein the component A comprises: isocyanate, hydroxyl-terminated polyether diol having a molecular weight of 2000-5000, hydroxyl-terminated polyether diol having a molecular weight of 200-1000, a plasticizer and a silane coupling agent, and the component B comprises: hydroxyl-terminated polyether polyol, a plasticizer, an organic solvent, a pigment filler, a catalyst, a curing agent, a high performance auxiliary agent and an acidic aid. According to the present invention, thepolyurethane waterproof material has advantages of high tensile strength, high elongation at break, high right angle tear strength, high bond strength, moisture heat resistance, aging resistance, chemical corrosion resistance, low cost, dense film sheet, high brightness, reliable construction and the like, has all the performances higher than the standards of TB / T 2965-2011 Technical specificationfor waterproof layer of railway concrete bridge, and is especially suitable for railway bridges.

The invention discloses a membrane humidifier for fuel cells, which comprises a cylindrical shell, humidification tubes, a first baffle and a second baffle plate, wherein each humidification tube adopts a two-layer structure; the outer layer of the humidification tube is an aramid paper tube; the inner layer of the humidification tube is a stainless-steel screen stencil; and the two ends of the humidification tube are respectively fixed on the first baffle and the second baffle plate and are sealed in the cylindrical shell, so as to form a tube side and a shell side. The invention further discloses a fuel cell device comprising the membrane humidifier. According to the membrane humidifier for fuel cells, two different gases are conveyed to the tube side and the shell side, and humidity exchange and temperature exchange are carried out through the tube walls of the humidification tubes, so that inlet air of the fuel cells can be humidified and heated effectively and the performance of the fuel cells can be played better; and the membrane humidifier is simple in preparation technology, excellent in performance, lower in cost and long in service life.

The invention provides a polypeptide probe based on photo-crosslinking and nano-metal particle self-assembly technologies. The polypeptide probe is modified with protein-post-translational modified polypeptide. According to the polypeptide probe, affinity recognition and enrichment capture processes are integrated, so that the convenient and efficient recognition and identification of a protein-post-translational modified binding protein or a compound of the binding protein. According to the polypeptide probe of the invention, a photo-crosslinking group is introduced into nano metal particles,so that a weak acting force between the polypeptide and the binding protein is converted into a strong covalent bond effect formed by the photo-crosslinking group, and therefore, the polypeptide probe can bear strong elution conditions and can capture proteins with low abundance and transient interaction; the influence of the modification of the photo-crosslinking group on a polypeptide frameworkis avoided, and therefore, the original structure and recognition characteristic of the polypeptide framework are well maintained, and influence on the binding specificity of the corresponding binding protein is greatly reduced. The invention further provides a preparation method of the polypeptide probe, and the application of the polypeptide probe to the identification of post-translational-modified binding proteins, the identification of interaction between protein modifications and the discovery of new protein-modified binding proteins.

Disclosed are phenanthrene-containing heterocyclic compounds shown as general formula (I) and preparation method therefor and application thereof on pesticides. The synthetic method of the compounds is simple and easy to industrialize. The phenanthrene-containing heterocyclic compounds can be used as plant virucides to inhibit tobacco mosaic virus, pepper virus, rice virus, tomato virus, sweet potato virus, potato virus, melon virus, maize dwarf mosaic virus and the like, particularly to inhibit tobacco mosaic virus. R1, R2, R3, X1-X7, m and n in general formula (I) are as defined in description.

The invention discloses a rhamnolipid-containing personal cleaning product and a preparing method thereof. The preparing method includes: subjecting a bacterium, Pseudomonas aeruginosa, to fermentation cultivation via a non-vertical fermentation tank so as to convert fresh vegetable oil into rhamnolipid, performing extracting, refining and concentrating to obtain rhamnolipid concentrate containing 90% to 95% of rhamnolipid, directly adding 0.1 to 0.5 part of citric acid, as pH regulator, 0.1 to 0.5 part of peppermint water, as flavoring agent, and the balance of distilled water or deionized water, as final concentrate viscosity regulator, into the 50 to 95 parts of the rhamnolipid concentrate, performing full mixing, allowing standing, and performing degassing to obtain the personal cleaning product. The pH is adjusted to 5.0 to 10.0. The repeated trials on the personal cleaning product show that the personal cleaning product has evident technical effect on skin cleaning and post-cleaning tactile improving and is widely applicable.

The present invention relates to a high-effective, low-toxicity and environment-protecting new-type plant source pesticide and miticide new medicine. The invented plant extract includes capillaries industrial alcohol extract and capillaries n-butyl alcohol extract, the pesticide and medicide active component of said capillaries alcohol extract is 4-methyl-7-umbelliferone. Besides, said invention also provides its preparation method and its concrete steps.

The invention belongs to the technical field of organic synthesis and particularly relates to a cyclamine alkylamide ferulate compound as well as a preparation method and application thereof. The preparation method comprises the following steps: enabling potassium phthalimide serving as a start raw material to react with 1-substituted-4-haloalkyl piperidine under the effects of a solvent and alkali to obtain a phthalimide alkylamine compound; performing hydrazinolysis of the phthalimide alkylamine compound and hydrazine hydrate to obtain a primary amine compound; and adding ferulic acid, a condensing agent and a solvent into the primary amine compound for a condensation reaction to obtain a product of cyclamine alkylamide ferulate compound. The cyclamine alkylamide ferulate compound provided by the invention is of a simple chemical structure, the chemical reactions in the preparation process are thorough, the product yield is high, the operation is convenient, the cost is low, and the product can be used for perfectly treating the neurodegenerative diseases.

The invention discloses a modified MXene / PVA flame-retardant composite material and a preparation method thereof, the flame-retardant composite material is formed by compounding a flame-retardant additive and a resin matrix, the resin matrix is polyvinyl alcohol resin, and the flame-retardant additive is modified MXene. The method comprises the steps: dispersing Mxene in deionized water, and carrying out ultrasonic treatment to obtain Mxene dispersion liquid; adding CTAB, and carrying out magnetic stirring reaction to obtain a mixed solution; adjusting the pH value of the mixed solution, carrying out magnetic stirring reaction, adding tetraethoxysilane, and carrying out magnetic stirring reaction to obtain a precipitate; dissolving the precipitate in an ethanol water solution, dropwise adding a silane coupling agent, carrying out magnetic stirring reaction, and washing to obtain modified MXene; dispersing polyvinyl alcohol in deionized water to obtain a polyvinyl alcohol solution; adding modified MXene; and uniformly dispersing and drying to obtain the multifunctional flame-retardant composite material. The composite material has excellent flame retardant property, good conductivity and electromagnetic shielding property, and can be used in the field of building coatings and other coatings.

The invention relates to a 4-phenyl para-alcohol oxime ether-containing oxazoline compound as shown in the general formula (I), preparation of the compound and an application of the compound in pesticides. The compound represents a novel concise, wide-spectral and high-efficiency insecticidal anti-mite bactericidal herbicide structure type. When used as a novel insecticidal anti-mite bactericidal herbicide, the 4-phenyl para-alcohol oxime ether-containing oxazoline compound can greatly control oriental armyworm, cotton bollworm, corn borer, plutella xylostella, beet armyworm and mosquito larvae, can greatly control Tetrangychus cinnabarinus, can greatly inhibit ten pathogenic bacteria including cucumber fusarium wilt, Cercospora arachidicola, Physalospora piricola Nose, Alternaria solani, Fusarium graminearumt, late blight of potato, sclerotinia sclerotioru, Botrytis cinerea, rice sheath blight and phytophthora capsici, and can control and eliminate weeds including rape, amaranth, barnyard grass and crab grass, wherein the meaning of R is as shown in the specification.

The invention provides a fluorescent probe based on quinoxalinone aryl sulfides as well as a preparation method and application thereof. A chemical structure of a fluorescent probe molecule is shown in formula (I) (shown in the specification), wherein R is selected from allyl and derivatives thereof, benzyl and derivatives thereof, fatty acid ester groups with the carbon atom number of 1-8 or fatty acid with the carbon atom number of 1-8; R1 is selected from alkoxy with the carbon atom number of 1-8, halogen or alkyl with the carbon atom number of 1-8; and R2 is aryl sulfides. The fluorescentprobe molecule is obtained by cyclizing o-phenylenediamine and derivatives thereof, carrying out nucleophilic substitution and carrying out aldol condensation reaction. The quinoxalinone derivative compound turns red fluorescence into green fluorescene after thioether is oxidized into sulfoxide in the presence of up-regulated heme oxidase and active oxygen in ferroptosis cells. The fluorescent probe provided by the invention can be directly added into a culture medium, then acts on cells and carries out detection, and also can be directly injected intravenously or intratumorally and play a role of animal in vivo detection.

It is an object of the invention to provide a optimized rational water treatment technique for chemically treating water to be treated. A representative water treatment apparatus is adapted for chemically treating water by using chemicals. In a water treatment apparatus, a disinfectant within a chemical cartridge dissolves out in water to be treated in a disinfecting chamber so that the water is disinfected. Further, a magnet is disposed within the chemical cartridge. The accommodated position of the magnet within the chemical cartridge is changed according to the remaining amount of the disinfectants. The magnetism of such magnet is detected by a magnetic sensor disposed on the outside of the chemical cartridge, so that information on consumption of the disinfectant can be detected.

The present invention relates to an oxazoline compound with a 4-phenly para-position containing a structure of thioether, sulphone, sulfilimine and sulfoximine represented by a formula (I), and preparation for the compound and an application of the compound as a pest and mite killing agent. The compound represents a novel and simple pest and mite killing agent structure type with simple preparation, a broad spectrum and high efficiency. The oxazoline compound with the 4-phenly para-position containing the structure of thioether, sulphone, sulfilimine and sulfoximine is used as a novel pest and mite killing agent which can perfectly prevent and control oriental armyworms, cotton bollworms, ostrinia nubilalis, and mosquito larvae, and can perfectly prevent and control mite eggs and baby mites of carmine spider mites. The formula (I) is shown in the description, wherein R' can be cyano, nitryl, trifluoroformoxyl or formamido; R'' can be hydrogen, cyano, nitryl, trifluoroformoxyl or formamido; and R can be heterocycle (substituted heterocycle), aryl (substituted aryl) or alkyl (branched aryl).

A compound represented by the general formula (M):(wherein R1 represents a substituted or unsubstituted aromatic heterocyclic group,R2 represents a hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 3 carbon atoms, OR3, N(R3)2, C(═O)OR3 or C(═O)N(R3)2,R3 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 4 carbon atoms,R4 represents a hydrogen atom, an oxygen atom or OR5, andR5 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an acyl group having 1 to 3 carbon atoms); ora pharmaceutically acceptable salt thereof is a cortistatin A analog which is useful as an active ingredient of medicaments for cancer prevention or treatment in that the analog can be mass-produced by chemical synthesis due to its simple chemical structure and retains the same biological activities as those of cortistatin A.

The present invention relates to a composition comprising an autophagy enhancement compound. Small molecules that are able to enhance autophagy and lysosome biogenesis by activating the gene TFEB which can prevent the accumulation of toxic protein aggregates in treating neurodegenerative diseases are disclosed.

A method for fabricating a semiconductor device includes the steps of forming a nitrogen-containing layer in an exposed portion of a copper interconnect formed in an insulating film provided on a substrate; and forming an interlayer insulating film on the nitrogen-containing layer through plasma CVD performed by using, as a material, an organic silicon compound having a siloxane (Si—O—Si) bond.

A compound represented by the general formula (M):(wherein R1 represents a substituted or unsubstituted aromatic heterocyclic group,R2 represents a hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 3 carbon atoms, OR3, N(R3)2, C(═O)OR3 or C(═O)N(R3)2,R3 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 4 carbon atoms,R4 represents a hydrogen atom, an oxygen atom or OR5, andR5 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an acyl group having 1 to 3 carbon atoms); ora pharmaceutically acceptable salt thereof is a cortistatin A analog which is useful as an active ingredient of medicaments for cancer prevention or treatment in that the analog can be mass-produced by chemical synthesis due to its simple chemical structure and retains the same biological activities as those of cortistatin A.

A method for synthesizing an organometallic compound, which is usefully utilized as a catalyst for manufacturing polyolefins by ring-opening metathesis polymerization of an olefin having strain in a molecule such as dicyclopentadiene or synthesizing epothilones by ring-dosing metathesis reaction, by an efficient and low cost synthesis method using a starting material which is easily available due to relatively simple chemical structure, and further without any possibility of coexistence of a vinylhetero compound or a vinyl compound exchanged which tends to accompany as an impurity in the system in conventional methods, characterized by reacting a starting material comprising a zero-valent transition metal complex (A) or a polyvalent transition metal complex (A′), a compound (B) or (B′) shown by the following general formula (1) or (4), respectively, and a neutral ligand (C) or (C′), in one step under non-reducing condition or reducing condition. R1Y1CR2X12  (1) R4Y2CR5X22  (4)

The invention discloses a class of aryl-acrylketone compound (formula a) containing 1,3,5-dioxazine heterocycle, a preparation method and application thereof. The structural formula of the class of compound is shown as formula a in the specification, wherein, in formula a, Y is the formula showed in the specification, wherein R is H, F, Cl, Br, CH3O, C2H5O, 2,4-Cl2, NO2, CH3. In formula a, R1 is CH3, C2H5, and CH(CH3)2. The compound in the invention has simple structure and is easy to prepare. The compound in the invention has good activity on pests such as aphid, plutella xylostella, tetranychus cinnabarinus and the like, and the activity of the majority of the compound in the invention is superior to the effective components of natural Chinese stellera root, the invention can be applied practically in agricultural production.

The invention discloses preparation and application of a heterogeneous binuclear metallic complex. The heteronuclear complex consists of an iridium complex and a manganese porphyrin complex; the structure formula of the heteronuclear complex is shown as follows. The complex is high in relaxivity and is capable of realizing magnetic resonance imaging application; and meanwhile, the complex is highin singlet oxygen quantum yield; ROS can be produced in cells, and the good photodynamic treatment can be confirmed by observing the change of the cellular morphology before and after the operation. The complex has a good application prospect in the magnetic resonance imaging and the photodynamics therapy.

The present invention relates to a composition comprising an autophagy enhancement compound. Small molecules that are able to enhance autophagy and lysosome biogenesis by activating the gene TFEB which can prevent the accumulation of toxic protein aggregates in treating neurodegenerative diseases are disclosed.

The invention relates to a hemigossypol derivative, a vergosin derivative, preparation of the hemigossypol derivative and the vergosin derivative and application to preventing plant viruses, killing bacteria and killing insects. Meaning of groups in the formula is shown in the description. The hemigossypol derivative and the vergosin derivative have excellent plant virus resistance, sterilization activity and insecticidal activity. Please see the molecular formula in the description.

The invention specifically relates to a combinatorial method for surfactant composition, namely, foaming agent with high selectivity and high foaming characteristics. The combinatorial method is characterized in that.

The invention belongs to the technical field of chemical synthesis, and more specifically relates to a preparation method of cyclic carbonates. The preparation method comprises following steps: 10 to 100mg of WO3 catalyst with oxygen vacancy, 10 to 50mg of a co-catalyst, 0 to 10ml of a solvent, and 0.05 to 1.0ml of an epoxy compound are delivered into a reaction kettle; carbon dioxide is used for replacing gas for 3 to 4 times, and stirring reaction is carried out for 3 to 15h at 20 to 130 DEG C under 0.1 to 1.0MPa carbon dioxide atmosphere so as to obtain a finished product. According to the preparation method, few kinds of raw materials are used; toxicity is low; chemical structure is simple; no pollution is caused; catalytic activity is high; reaction conversion rate is as high as 96%; selectivity is as high as 99%; the catalyst can be recycled for at least 7 times; reaction temperature and pressure are both low; conditions are mild; one-step synthesis is realized; and the preparation method is suitable to be popularized.

Disclosed is a composition for prevention and treatment of alopecia or for hair growth, comprising a phytosphingosine-1-phosphate derivative or a pharmaceutically acceptable salt thereof as an active ingredient. Also, a medicine comprising the composition and a quasi-drug comprising the composition are provided.

The invention relates to a phosphorescent iridium complex with a lysosome targeting function and its preparation method and use and belongs to the technical field of organic photoelectric materials. The phosphorescent iridium complex comprises a C^N ligand, a metal core and an alkyl chain-containing auxiliary ligand and has a structural formula shown in the description. The phosphorescent iridium complex can be excited by visible light, produce emission light in a near infrared area and reduce an excitation light source-caused damage to a biological sample and has deep tissue penetrating depth. The phosphorescent iridium complex has good photobleaching resistance and realizes long-term effective observation of cell tissue. The phosphorescent iridium complex can be used in the field of lysosome labeling and bioimaging, has a simple chemical structure and good biocompatibility and is a good lysosome targeting phosphorescent probe.