Extract of combined Chinese traditional medicinal herb for curing diseases of respiratory system and extracting method

A technology for respiratory diseases and Chinese herbal medicines, applied in respiratory diseases, drug combinations, medical formulas, etc., can solve the problems of uncontrollable quality and curative effect, inconvenient medication, unsatisfactory curative effect, etc., and achieve the goal of mass production and storage transport, easy to take, stable and controllable quality and curative effect

Active Publication Date: 2009-09-23
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many new drugs have been developed for respiratory diseases in recent years, but the curative effect is still not satisfactory
In the prior art, although there are some clinical experience in formulating prescriptions, the ingredients in the medicinal prescriptions cannot control the stable quality and curative effect due to unpredictable factors such as place of origin and climate.
But medication is extremely inconvenient

Method used

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  • Extract of combined Chinese traditional medicinal herb for curing diseases of respiratory system and extracting method
  • Extract of combined Chinese traditional medicinal herb for curing diseases of respiratory system and extracting method
  • Extract of combined Chinese traditional medicinal herb for curing diseases of respiratory system and extracting method

Examples

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Effect test

Embodiment 1

[0017] Embodiment 1. This embodiment is an extract and an extraction method of a combination of Chinese medicinal materials for the treatment of respiratory diseases. The weight (gram) formula of the combined Chinese medicinal material extract raw material is:

[0018] Mulberry leaf 500 Peucedanum 500 Scutellaria baicalensis 500 Almond 500

[0019] Bellflower 200 Fritillaria 500 Loquat Leaf 500 Nansha Ginseng 500

[0020] Ginger Pinellia 500 Tangerine Peel 300 Licorice 150

[0021] (a) mulberry leaves and tangerine peel add 6 times the amount of water to soak for 3 hours, steam distillation extracts the volatile oil, collects 6 times the amount of distillate, and the distillate is redistilled-refrigerated to obtain the mulberry leaf and tangerine peel volatile oil;

[0022] (b) Take the above-mentioned mulberry leaves and dried tangerine peel distilled medicinal dregs, peucedanum, loquat leaves, Nansha ginseng, ginger pinellia, and licorice, soak them in water for 1 hour, and...

Embodiment 2

[0023] Embodiment 2. This embodiment is an extract and extraction method of a combination of Chinese medicinal materials for the treatment of respiratory diseases. According to the weight ratio of β-cyclodextrin: mulberry leaf and tangerine peel volatile oil is 8: 1, the packaged at 30 ℃ Under the combination temperature, the mulberry leaves and tangerine peel volatile oil obtained in step (a) of Example 1 were clathrated with β-cyclodextrin, and the inclusion time was 3 hours to obtain the β-cyclodextrin inclusion complex of mulberry leaves and tangerine peel volatile oil Then the liquid extract of the combined Chinese medicinal materials obtained in the step (b) of Example 1 is concentrated, dried, pulverized and added to the β-cyclodextrin inclusion complex of mulberry leaves and tangerine peel volatile oil, mixed evenly, and granulated to make Granules, capsules and tablets as described in Pharmacy.

Embodiment 3

[0024] Embodiment 3. This embodiment is an extract and extraction method of a combination of Chinese medicinal materials for the treatment of respiratory diseases. According to the weight ratio of β-cyclodextrin: mulberry leaf and tangerine peel volatile oil is 6:1, the packaged at 20 ℃ Under the combination temperature, the mulberry leaves and tangerine peel volatile oil obtained in step (a) of Example 1 were clathrated with β-cyclodextrin, and the inclusion time was 2.5 hours to obtain the β-cyclodextrin inclusion complex of mulberry leaves and tangerine peel volatile oil Then the liquid extract of the combined Chinese medicinal materials obtained in the step (b) of Example 1 is concentrated, dried, pulverized and added to the β-cyclodextrin inclusion complex of mulberry leaves and tangerine peel volatile oil, mixed evenly, and granulated to make Granules, capsules and tablets as described in Pharmacy.

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Abstract

An extract and extraction method of a combination of Chinese medicinal materials for the treatment of respiratory diseases, mulberry leaves and tangerine peel steam distillation method to extract volatile oil; mulberry leaves and tangerine peel distilled medicinal residues and Peucedanum, loquat leaves, Nansha ginseng, ginger pinellia, licorice Add water to soak, decoct, and concentrate the filtrate to obtain water extract; Scutellaria baicalensis, almond, Fritillaria, Platycodon grandiflora, soak in ethanol, reflux extraction, filtrate decompresses to recover ethanol, concentrate to obtain alcohol extract; combine water extract and alcohol extract Obtain liquid extracts of combined Chinese medicinal materials. It is made into granules, capsules, tablets and soft capsule oral liquid as described in pharmacy. The invention has the advantages of high curative effect, reduced medication volume, and is convenient for patients to take; has stable and controllable quality and curative effect; and overcomes the shortcomings of decoctions. Experiments have proved that the preparation of the present invention has definite curative effects on respiratory diseases such as acute bronchitis and acute exacerbation of chronic bronchitis.

Description

technical field [0001] The invention relates to an extract and an extraction method of combined Chinese medicinal materials, in particular to an extract and an extraction method of combined Chinese medicinal materials for treating respiratory diseases. Background technique [0002] Respiratory diseases are common and frequently-occurring diseases. With the development of modern industry, air pollution is becoming more and more serious. Harmful substances from the outside, such as various harmful gases, dust, allergenic microorganisms and allergens are directly inhaled into the lungs, which increases the morbidity and mortality of the respiratory system. In 1998, a sample survey in my country's rural areas showed that the death rate of respiratory diseases ranked first, accounting for 25% of the total death rate. Respiratory diseases also rank first in residents' hospital visits in Shanghai. According to incomplete statistics, the adult incidence rate of this disease is 5%,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8967A61K36/8888A61K36/752A61K36/736A61K36/73A61K36/605A61K36/539A61K36/484A61K36/342A61K36/34A61K36/23A61K9/16A61K9/20A61K9/48A61P11/00
Inventor 蔡宝昌潘扬章晨峰曹亮
Owner JIANGSU KANION PHARMA CO LTD
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