Oral administered medicinal composition and its preparation and usage

A kind of use and technology of traditional Chinese medicine, applied in the field of oral medicine for the treatment of uterine fibroids, can solve the problems of reducing the curative effect of the prepared medicine, lack of preparation method, strong purging effect, etc., achieve wide therapeutic use, effective pharmacological effect, and less adverse reactions Effect

Active Publication Date: 2010-03-24
成都倍特得诺药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the weak point of this patent is that the rhubarb used for purging fire and detoxification, clearing heat and promoting dampness is not enough, and the purging effect is too strong, which reduces the curative effect of the medicine and increases adverse reactions; another weak point of this patent The weight ratio of each raw material is unreasonable; another shortcoming of this patent is that there is no reasonable preparation method, and it cannot be implemented and applied in production

Method used

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  • Oral administered medicinal composition and its preparation and usage
  • Oral administered medicinal composition and its preparation and usage
  • Oral administered medicinal composition and its preparation and usage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: the preparation of medicine capsule of the present invention

[0015] Take 250g of cooked rhubarb, 200g of ground beetle, 205g of leech, 175g of peach kernel, 160g of Puhuang, 122g of scutellaria baicalensis, 175g of Citrus aurantium, 240g of oyster, 230g of rehmannia glutinosa, 186g of white peony root, 60g of licorice, among which cooked rhubarb, ground beetle, leech and cattail Add 10 times the amount of water to soak for 2 hours, add peach kernels and scutellaria baicalensis to boil for 1.5 hours, add 8 times the amount of water to decoct the dregs of the medicine for 1 hour, The decoctions are filtered and combined, concentrated under reduced pressure to a relative density of about 1.20 (65°C); the oysters are decocted and concentrated in the same way, combined with the above-mentioned concentrated solution, dried in vacuum, and crushed to obtain extract powder. Take 1 part of extract powder and 0.25 part of starch, granulate with appropriate amount o...

Embodiment 2

[0016] Embodiment 2: the preparation of pharmaceutical tablet of the present invention

[0017] Take 125g of cooked rhubarb, 100g of ground beetle, 105g of leech, 90g of peach kernel, 82g of Puhuang, 60g of scutellaria baicalensis, 86g of Citrus aurantium, 120g of oyster, 115g of rehmannia glutinosa, 94g of white peony root, 31g of licorice, among which cooked rhubarb, ground beetle, leech and cattail Add 10 times the amount of water to soak for 2 hours, add peach kernels and scutellaria baicalensis to boil for 1 hour, add 8 times the amount of water to decoct the dregs of the medicine for 1 hour, The decoction is filtered and combined, concentrated under reduced pressure to a relative density of about 1.20 (65°C); the oysters are decocted and concentrated in the same way, combined with the aforementioned concentrated solution, and the starch with an extract amount of about 35% is used as a base material, sprayed and dipped The paste is granulated in one step, granulated, comp...

Embodiment 3

[0018] Embodiment 3: the preparation of medicine mixture of the present invention

[0019] Take 70g of cooked rhubarb, 65g of ground beetle, 55g of leech, 50g of peach kernel, 48g of Puhuang, 36g of Scutellaria baicalensis, 50g of Citrus aurantium, 72g of oyster, 75g of rehmannia glutinosa, 48g of white peony root, 18g of licorice, among which cooked rhubarb, ground beetle, leech and cattail Add 11 times the amount of water to soak the eight herbs such as Citrus aurantium, Rehmannia glutinosa, Radix Paeoniae Alba, and Glycyrrhizae for 3 hours, add peach kernels and scutellaria baicalensis for 2 hours after boiling, add 9 times the amount of water to boil for 1.5 hours, The decoctions are filtered and combined, concentrated under reduced pressure to a relative density of 1.15 to 1.20 (60°C), added ethanol to make the alcohol content reach 65% to 70%, left to stand for 24 hours and then filtered, the filtrate is decompressed to recover ethanol, centrifuged, and taken Add 0.4g of...

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Abstract

The invention discloses an oral medication for treating diseases including hysteromyoma, its preparation process and application, the medicament is prepared from traditional Chinese medicinal raw materials including rhubarb horsetails, wood louse, leeches, peach kernels, cattail pollen. The preparation comprises the steps of refining through stepwise grilling, then charging different pharmaceutically acceptable excipients. The medicament has the actions of resisting estrogenic hormones, anti-inflammatory and haemostasis, it also has function of immunological enhancement and improvement.

Description

technical field [0001] The invention relates to an oral pharmaceutical composition and its preparation method and application, in particular to an oral medicine for treating uterine fibroids, which is produced and prepared by using traditional Chinese medicine as the main raw material and adopting modern preparation technology. Background technique [0002] Uterine fibroids (including uterine intramural fibroids and subserosal fibroids, etc.) are the most common benign tumors in female reproductive organs. They occur in middle-aged and menopausal women aged 30 to 50. The common clinical symptom is abnormal uterus Bleeding, often causing anemia due to excessive bleeding, is a common and frequently-occurring disease that threatens women's health. Uterine fibroids belong to the category of "disease accumulation" in traditional Chinese medicine. The pathogenesis is mostly caused by internal stagnation of blood stasis. Clinical symptoms such as abdominal pain, heavy menstrual flo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61K36/804A61K36/75A61K36/73A61K36/71A61K36/708A61K36/539A61K36/484A61K35/64A61K35/62A61K35/56A61P15/00A61P29/00A61P7/04A61P7/06A61P37/04A61K35/618
Inventor 张沛冯华祥芮旭东周道铨
Owner 成都倍特得诺药业有限公司
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