Medicine-carrying contact lens and preparation method thereof

A contact lens and drug-loading technology, which is applied in the fields of medical formula, glasses/goggles, drug combination, etc., can solve the problems of easy loss of eye drops and poor tolerance, and achieve the effect of delayed release and simple preparation process
CN100596332CInactive Publication Date: 2010-03-31SOUTHEAST UNIV
8 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTHEAST UNIV
Publication Date
2010-03-31
Estimated Expiration
Not applicable Β· inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a drug-loaded contact lenses and a corresponding preparation method. The drug-loaded contact lenses are obtained firstly through UV-curing or heat-curing and then through drug-liquid immersion. The drug-loaded contact lenses can be particularly defined as a combination of a contact lenses material containing cyclodextrin and drug molecules and comprise the contact lenses formed by combining a crosslinked polymer hydrogel formed by copolymerizing mono-substituted cyclodextrin monomers, polymerization monomers and crosslinkers with one kind or a plurality of acetazolamide, methazolamide, puerarin or prostaglandin. The characteristic of forming inclusion compounds between the cyclodextrin molecules and drug molecules is adopted to increase the quantity of loaded drugsso as to reduce the stimulation to eyes by drugs and control the drug release speed for eye diseases of curing glaucoma, etc.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a drug-loaded contact lens and a preparation method thereof, which is characterized in that the drug-loaded contact lens is obtained through ultraviolet light or heat-initiated curing, and the drug-loaded contact lens is obtained by soaking in a drug solution. Specifically, in the present invention, single-substituted cyclodextrin molecules are introduced into contact lens materials, and the ability of cyclodextrin molecules to form clathrates with drug molecules is utilized to increase drug loading and control the release rate of drugs. It is especially suitable for ocular administration of lipophilic drugs, drugs with strong eye irritation and drugs with poor stability, and used to treat eye diseases such as glaucoma. Background technique

[0002] At present, soft contact lenses are mainly divided into hydrophilic contact lenses and high oxygen permeability contact lenses. Hydrophilic contact lenses mainly use poly-2-hydroxy...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More