Therapeutic or preventive agent for diabetic neuropathy
A technology for neurological disorders and diabetes, which is applied in the direction of nervous system diseases, metabolic diseases, sensory diseases, etc., and can solve problems such as unknown spherical activated carbon and unknown effectiveness of diabetic neurological disorders.
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manufacture example 1
[0087]
[0088] A porous spherical carbonaceous material was obtained in the same manner as the method described in Example 1 of Japanese Patent No. 3522708 (JP-A-2002-308785). The specific operation is as follows.
[0089] 68 kg of petroleum-based pitch (softening point = 210° C.: quinoline insoluble content = 1% by weight or less; H / C atomic ratio = 0.63) and 32 kg of naphthalene were placed in a pressure vessel with an internal volume of 300 L with a stirring blade , after melt-mixing at 180°C, cooling to 80-90°C and extruding to obtain a rope-shaped molded body. Next, the rope-shaped molded body is pulverized so that the ratio of the diameter to the length becomes approximately 1-2.
[0090] In an aqueous solution in which 0.23% by weight of polyvinyl alcohol (saponification degree = 88%) was dissolved and heated to 93°C, the above-mentioned pulverized product was added, dispersed by stirring and spheroidized, and cooled with water instead of the above-mentioned aqueous...
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