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Pidotimod injection and the producing method thereof

A technology of pidotimod and a production method, which is applied in the field of pharmaceutical injections, can solve problems such as the lack of pidotimod injection, and achieve the effects of no vascular irritation, allergic reactions, and fast curative effect.

Inactive Publication Date: 2007-10-31
沈阳双鼎制药有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there are only pidotimod in oral liquid, powder, granules, tablets, etc. on the market, and there is no pidotimod injection

Method used

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  • Pidotimod injection and the producing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The production method of pidotimod injection, taking the full amount of 5000ml injection as an example, is characterized in that: get 400g pidotimod medicine, add 2500g water for injection, add 72g sodium hydroxide to make it dissolve, add 40g sodium chloride, Then add water for injection to 5000ml, then add 5g of activated carbon, stir for 30 minutes and then filter, adjust the pH value to 6.0-8.0, then filter with a 0.22μm microporous membrane, pack according to the set specifications, and sterilize with circulating steam Get it later.

Embodiment 2

[0025] The production method of pidotimod injection, taking the full amount of 5000ml injection as an example, is characterized in that: take 400g of pidotimod drug, add 4000ml of water for injection, add 72g of sodium hydroxide to dissolve it, and then add water for injection to 5000ml , then add 5g of activated carbon, stir and filter with filter paper, adjust the pH value to 6.0-8.0, then filter with a 0.22μm microporous membrane, pack according to the set specifications, and sterilize with circulating steam.

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Abstract

The invention discloses a Pidumode injection, which is characterized by the following: producing solution agent with Pidumode medicine and medicinal carrier; adjusting pH value at 6. 0-8. 0; setting volume of each packing unit at 2-500ml; incorporating 100-800mg Pidumode; forming salt with Pidumode and caustic soda; possessing good water-solubility and medicinal crop with the same as Pidumode; easy-degrading to aminoglutaric acid and thiazolidinecarboxylic acid with Pidumode; adjusting the pH value of the solution to near neutral; stabilizing the quality of product. This invention can be used to intravenous injection.

Description

technical field [0001] The invention belongs to a production method of pharmaceutical injections, in particular to a production method of pidotimod injection. Background technique [0002] The immunity of the human body includes specific immunity (refers to the targeted resistance of the human body to a certain pathogen) and non-specific immunity, which directly affects the health of the human body. In real life, due to one reason or another, the immunity of various groups of people is often low. The blood concentration of exogenous immunoglobulin in children over half a year old is low, the immune system is not yet fully developed, and recurrent upper respiratory tract infections often occur due to climate change, which affects the physical growth and psychological development of children to a certain extent. The immune system of the elderly is physiologically degraded, and the cellular immune function is low, which is prone to recurrent respiratory tract infections, cance...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/05A61K9/08A61P37/04A61P11/00A61P13/00A61P27/16A61P35/00
Inventor 何仲贵马占之孙镭芹李志强李冰
Owner 沈阳双鼎制药有限公司
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