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Pharmaceutical composition for gestation reaction and method of preparing the same

A technology of pregnancy reaction and composition, applied in the field of medicine, to achieve the effect of simple preparation process, meet clinical needs, and increase the variety of clinical drugs

Inactive Publication Date: 2008-03-12
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, there is no report on the use of Daidaihua, Bergamot, Amomum, Sugeng, and Jiaobaizhu for the preparation of drugs for the treatment of pregnancy reactions by interacting with each other.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1: the preparation of pharmaceutical composition tablet of the present invention

[0049] prescription one

[0050] Daidaihua 15g, Bergamot 15g, Amomum 6g, Sugan 10g, Jiaobaizhu 10g

[0051] Replace Daihua, Bergamot, Amomum, and Peregrine with 5 times the amount of water, extract the volatile oil by steam distillation for 5 hours, collect the volatile oil and medicinal liquid, take the medicinal residue, combine with Jiaobaizhu, add water and decoct twice, After 2 hours, add 12 times the amount of water, combine the decoction liquid, filter, combine the filtrate with the above liquid medicine, concentrate under reduced pressure, vacuum dry, and pulverize to obtain extract powder, and set aside; take the above volatile oil and cyclodextrin clathrate, Dried, mixed with the above-mentioned extract powder, granulated, dried, pulverized to obtain medicinal powder, added with binder, disintegrant and lubricant to make granules, dried, and pressed into tablets. ...

Embodiment 2

[0055] Embodiment 2: the preparation of pharmaceutical composition granule of the present invention

[0056] prescription one

[0057] Daidaihua 12g, Bergamot 12g, Amomum 3g, Sugeng 8g, Jiaobaizhu 8g

[0058] Replace Daihua, Bergamot, Amomum, and Peregrine with 5 times the amount of water, extract the volatile oil by steam distillation for 5 hours, collect the volatile oil and medicinal liquid, take the medicinal residue, combine with Jiaobaizhu, add water and decoct twice, After 2 hours, add 12 times the amount of water, combine the decoction liquid, filter, combine the filtrate with the above liquid medicine, concentrate under reduced pressure, vacuum dry, and pulverize to obtain extract powder, and set aside; take the above volatile oil and cyclodextrin clathrate, Dry, mix with the above-mentioned extract powder, granulate, dry, pulverize to obtain medicinal powder, add sugar powder and binder to make granules.

[0059] Prescription two

[0060] Daidaihua 16g, Bergamot...

Embodiment 3

[0062] Embodiment 3: the preparation of pharmaceutical composition capsule of the present invention

[0063] prescription one

[0064] Daidaihua 17g, Bergamot 17g, Amomum 8g, Sugan 12g, Jiaobaizhu 12g

[0065] Replace Daihua, Bergamot, Amomum, and Peregrine with 5 times the amount of water, extract the volatile oil by steam distillation for 5 hours, collect the volatile oil and medicinal liquid, take the medicinal residue, combine with Jiaobaizhu, add water and decoct twice, After 2 hours, add 12 times the amount of water, combine the decoction liquid, filter, combine the filtrate with the above liquid medicine, concentrate under reduced pressure, vacuum dry, and pulverize to obtain extract powder, and set aside; take the above volatile oil and cyclodextrin clathrate, Dry, mix with the above-mentioned extract powder, granulate, dry, and pulverize to obtain a medicinal powder, add a binder to make granules, and pack into hard capsules.

[0066] Prescription two

[0067] Da...

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PUM

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Abstract

The present invention pertains to the art of medical technology and discloses a medicine combination and a preparation meod for pregnancy reaction. The raw medicine materials of the medicine combination include seville orange flower, finger citron flower, villous amomum fruit, perilla stem and burnt largehead atractylode. The present invention with functions of clearing liver and stomach, controlling nausea and vomiting and preventing abortion is used for treating naupathia, nausea, vomiting and anorexia in pregnancy. The medicine combination can be made into any acceptable form in clinic or pharmacology, preferably oral form. The property of the raw medicine materials of the medicine combination gives attention to liver, stomach, spleen, lung and kidney, so that the drug property and the functions are more extensive to treat both manifestation and root cause of disease. In addition, the efficacy of the medicine materials has no toxic side effects, thus ensuring the safety of pregnant women.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for pregnancy response and a preparation method thereof. 2. Background technology [0002] Pregnancy reaction refers to symptoms such as food selection, loss of appetite, mild nausea and vomiting, dizziness, and burnout in the first trimester of pregnancy, also known as early pregnancy reaction. There are various theories about the causes of pregnancy reactions. If someone thinks that the pregnancy reaction is related to the action of human chorionic gonadotropin (hCG), the evidence to support this view is that the time of pregnancy reaction coincides with the appearance and disappearance of human chorionic gonadotropin (hCG) in the blood of pregnant women; Some people also think that the pregnancy reaction is related to autonomic dysfunction; some even think that the pregnancy reaction is caused by toxins produced by the placenta or ...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P15/00A61P1/08
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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