Dosage regimen for prasugrel

A technology of prasugrel hydrochloride and medicinal salts, which can be used in medical formulas, drug combinations, extracellular fluid diseases, etc., can solve plaque rupture and other problems, and achieve the effect of preventing the occurrence or recurrence of vascular diseases
CN101198329AInactive Publication Date: 2008-06-11ELI LILLY & CO
4 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ELI LILLY & CO
Publication Date
2008-06-11
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Abstract A dosage regimen for treating vascular disease in a human comprising the steps of administering a loading dosage of about 30 mg to 70 mg of loading dose of prasugrel or a pharmaceutically acceptable salt thereof, and thereafter administering a daily dosage regimen of about 7.5 mg to 15 mg maintenance dose of prasugrel or a pharmaceutically acceptable salt thereof.
Need to check novelty before this filing date? Find Prior Art

Description

field of invention

[0001] The present invention relates to dosing regimens for administering prasugrel to a patient in need thereof. Background of the invention

[0002] Vascular disease, including myocardial infarction and ischemic stroke, is a leading cause of death and disability. Although the processes leading to vascular disease are complex and not fully understood, the basic etiology shared by many theories includes atherosclerosis due to the formation of atherosclerotic lesions and plaque rupture leading to thrombosis or thromboembolism.

[0003] 2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (prasugrel)—— An adenosine diphosphate (ADP) receptor antagonist - a potent inhibitor of ADP-mediated platelet aggregation in vivo. US Patent 5,288,726 discloses tetrahydrothienopyridine derivatives including prasugrel. US Patent 6,693,115 B2 discloses acid addition salts of prasugrel. US Patent Publication 2004 / 0024013 Al discloses...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More