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Medicament for treating cough

A technology of medicines and active ingredients, applied in the field of medicines for treating cough, can solve the problems of lack of evidence materials for clinical trials, etc., and achieve the effects of low cost, easy portability and definite curative effect

Inactive Publication Date: 2008-06-18
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Application No. 01102033.4 on January 22, 2001, Publication No. CN1366894A on September 4, 2002 disclosed "a nano-pure lung-clearing and anti-inflammatory drug and its preparation method", but there is no evidence of clinical trials

Method used

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  • Medicament for treating cough
  • Medicament for treating cough
  • Medicament for treating cough

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: the medicine for the treatment of cough (trade name: cough ointment)

[0030] Raw material prescription:

[0031] Radix Ginseng 400g Ophiopogon japonicus 400g Polygonatum 400g Mulberry leaves 400g

[0032] Licorice 400g Trichosanthin 400g Raw lentils 400g

[0033] Preparation method: in GMP purification workshop:

[0034] A. Extraction process:

[0035] (a) Add 5 times the amount of 95% ethanol to Adenophora, Ophiopogon japonicus, Polygonatum Polygonatum and other three herbs, heat and extract for 1.5 hours, filter to obtain alcohol extract and residue, recover ethanol from alcohol extract to obtain extract to relative density 1.35-1.40, 60°C;

[0036] (b) The other four herbs such as mulberry leaves, licorice, trichosanthin, raw lentils and the residues of the above ethanol extraction are decocted twice with 7 times the amount of water, the first time is 1.5 hours, the second time is 1 hour, filtered and combined twice The filtrate was heated and con...

Embodiment 2

[0041] Embodiment 2: the medicine for the treatment of cough (trade name: antitussive cataplasm)

[0042] Raw material prescription:

[0043] Radix Ginseng 400g Ophiopogon japonicus 400g Polygonatum 400g Mulberry leaves 400g

[0044] Licorice 400g Trichosanthin 400g Raw lentils 400g

[0045] Preparation method: in GMP purification workshop:

[0046] A. Extraction process:

[0047] (a) Add 5 times the amount of 95% ethanol to Adenophora, Ophiopogon japonicus, Polygonatum Polygonatum and other three herbs, heat and extract for 1.5 hours, filter to obtain alcohol extract and residue, recover ethanol from alcohol extract to obtain extract to relative density 1.35-1.40, 60°C;

[0048] (b) The other four herbs such as mulberry leaves, licorice, trichosanthin, raw lentils and the residues of the above ethanol extraction are decocted twice with 7 times the amount of water, the first time is 1.5 hours, the second time is 1 hour, filtered and combined twice The filtrate was heated ...

Embodiment 3

[0054] Embodiment 3: investigation on the stability of the medicinal ointment for the treatment of cough

[0055] According to the "Technical Requirements for New Drug Research of Traditional Chinese Medicine" promulgated and implemented by the State Drug Administration, the technical requirements for quality stability research of new traditional Chinese medicines are stipulated. The ointment and cataplasm for treating cough are made according to the established process, and the properties, moisture retention, content and microbiological inspection items are observed at room temperature. The results show that all the control indicators meet the national ointment quality standards, and the quality is stable after being placed at room temperature for six months.

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Abstract

The invention discloses a medicine for treating cough. The effective ingredients contain Radix Glehniae, Radix Ophiopogonis, Rhizoma Polygonati Odorati, Folium Mori, Radix Glycyrrhizae, Radix Trichosanthis and Semen Lablab Album seven drugs. The effective components in the prescription are fully utilized through the preparation process in which parts of the drugs are extracted by ethanol and parts of the drugs are extracted by water, at the same time, the effective components are purified through effective preparation technology. The clinical tests show that the invention has more than 90 percent of cure rate to URI, acute and chronic bronchitis, and to cough and phlegm and hyperpnea and breathlessness caused by lung infection. The invention is an external-use paste which has the advantages of accurate effect, convenient carrying, functions of clearing lung and removing phlegm and relieving cough and asthma, and evident effect on treating cough.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a medicine made from Chinese medicinal materials. Medicines for treating cough. technical background [0002] Clinically, patients with lung disease often have symptoms such as shortness of breath, fatigue, cough, hemoptysis, and chest pain. The drugs used to treat both Qi and Yin deficiency and Yin deficiency and internal heat type lung disease have been reported in the literature. At present, there are the following types: [0003] 1. The newly edited national Chinese patent medicine, July 2002, 1st edition, page 1016 included "Yifei Qinghua Paste", which reported that the components were composed of: Astragalus, Codonopsis, Adenophora, Ophiopogon japonicus, Agrimony, Boxer Ginseng, Patrinia, Hedyotis diffusa, Chuan Fritillaria, Aster, Campanulaceae, bitter almonds, functions and indications: nourishing qi and nourishing yin, clear...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/06A61K9/70A61P11/14
Inventor 李建民杨吉田郝彬
Owner TIANJIN ZHONGBAO PHARMACY
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